Protein Alignment Camk2a and Drak

DIOPT Version :9

• Sequence 1: XP_006525604.1
• Gene: Camk2a / 12322
• MGIID: 88256
• Length: 489
• Species: Mus musculus
• Sequence 2: NP_001162723.1
• Gene: Drak / 32097
• FlyBaseID: FBgn0052666
• Length: 674
• Species: Drosophila melanogaster
• Alignment Length: 503
• Identity: 125/503 - (24%)
• Similarity: 215/503 - (42%)
• Gaps: 82/503 - (16%)

Mouse     4 ITCTRFTEEYQLFE-ELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLEREARICRLL 67
            ::|....|.|::.: ...:|.|:.|||.:....|..:|||.:..::.:....::::.|..:..|.
  Fly    27 VSCPDINEIYEVEQTPFARGKFAAVRRAIHKNTGSHFAAKFLKRRRRAQSSDKEIKHEIAVLMLC 91

Mouse    68 K-HPNIVRL---HDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQ 128
            : ..|||.|   |::.|:..   |:.:|.|||||...:...|..:||.|.||::::|:|:...|.
  Fly    92 EGEDNIVNLNAVHETRSDTA---LLLELATGGELQTILDNEECLTEAQARHCMREVLKALKFLHD 153

Mouse   129 MGVVHRDLKPENLLLASKLKGAAVKLADFGLA-IEVEGEQQAWFGFAGTPGYLSPEVLRKDPYGK 192
            ..:.|.||||:|:|||.:.....:||.|||:: :..||....  ..||||.|::||||:.:|...
  Fly   154 RSIAHLDLKPQNILLAGERIEDGLKLCDFGISRVVCEGINVR--EMAGTPDYVAPEVLQYEPLSL 216

Mouse   193 PVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTVTPEAKDLINKMLTINPS 257
            ..|:|:.||:.|:||.|:.||..:.:...:..|...|..||...:..|:|.|.|.|.:.|.|.|:
  Fly   217 LTDIWSVGVLTYVLLSGFSPFGGDTKQETFLNISQCALTFPDNLFGGVSPVAIDFIRRALRIKPN 281

Mouse   258 KRITAAEALKHPWISHRSTVASCMHRQETVDCLKK------------------------------ 292
            .|:.|...|.|.|:....::...::.|...|..::
  Fly   282 DRMNATGCLDHIWLKDDCSLDRQIYLQPQSDAEEEEEEDVDDDVEDEEEEEQVEEEEEETQNVEE 346

Mouse   293 --FNARRKLKGAILTTMLATRNFSGGK---SGGNKKNDGVKKRKSSSSVQLMESSESTNTTIEDE 352
              ..|.::.:..:....||.......|   :|.::.|.|....|...:...::|:.|:.||
  Fly   347 PTTEAPQQQQQPVQQHQLAKSGQIHSKPTHNGHHRANSGGSISKIPIATSKLQSTPSSETT---- 407

Mouse   353 DTKVRKQEIIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRN 417
             |.:          ..:.:.|||.....|::..|...|.:.:.               ||.::..
  Fly   408 -TAI----------HTLTSNSNGHVHKPTQIVTPTRRASDSDK---------------ENTYTAT 446

Mouse   418 --SKPVHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEET 463
              .|||.|..|...   .|.|.|.:. ..:|.:.||...|:..:...|
  Fly   447 FVKKPVATIQLGSS---NGIEDATVV-ATLTLFPDAPTTPKVIRKTPT 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Camk2a	XP_006525604.1	STKc_CaMKII	11..302	CDD:270988	91/328 (28%)
		CaMKII_AD	357..484	CDD:285524	21/109 (19%)
Drak	NP_001162723.1	STKc_DRAK	28..295	CDD:271008	88/271 (32%)
		S_TKc	45..295	CDD:214567	85/254 (33%)
		PHA03255	379..>554	CDD:165513	29/146 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910