DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RacGAP84C and arhgap32b

DIOPT Version :9

Sequence 1:	NP_476704.1	Gene:	RacGAP84C / 117503	FlyBaseID:	FBgn0045843	Length:	384	Species:	Drosophila melanogaster
Sequence 2:	XP_009293685.1	Gene:	arhgap32b / 569434	ZFINID:	ZDB-GENE-091204-147	Length:	1956	Species:	Danio rerio

Alignment Length:	164	Identity:	46/164 - (28%)
Similarity:	75/164 - (45%)	Gaps:	14/164 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   147 GC-LSDYAPRVAPMVPALIVHCVTEIEARGLQQEGLYRVSSTREKCKRLRRKLLRGKSTPHLGN- 209
            || |.::.......||.::..|...||..|: .:|:||:|......::||.: ...:..|.|..
Zfish   410 GCDLGEHLLNSGHDVPQVLKSCTEFIEKHGV-VDGMYRLSGIASNIQKLRHE-FDSEQIPDLTKD 472

  Fly   210 ---KDTHTLCCCVKDFLRQLVHPLIPIYHRRDFEE---ATRHEDRLAVEMAVYLAVLELHQAHRD 268
               :|.|.:....|.:.|:|.:||:.......|.|   |...|:||   :.::..:.:|...|..
Zfish   473 VYIQDIHCVGSLCKLYFRELPNPLLTYQLYEKFSEAVSAATDEERL---IKIHDVIQQLPPPHYR 534

  Fly   269 TLAYLMLHWQKIAE-SPAVRMTVNNLAVIFAPTL 301
            ||.:||.|...:|. |....|...|||:::||.|
Zfish   535 TLEFLMRHLSHLATFSYVTNMHTKNLAIVWAPNL 568

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RacGAP84C	NP_476704.1	C1_1	87..139	CDD:278556
RacGAP84C	NP_476704.1	RhoGAP_MgcRacGAP	142..330	CDD:239847	46/164 (28%)
arhgap32b	XP_009293685.1	PX_domain	124..238	CDD:295365
		SH3_ARHGAP32_33	260..313	CDD:212769
		RhoGAP_CdGAP	407..601	CDD:239849	46/164 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3564
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900