Protein Alignment AP2S1 and or

DIOPT Version :10

• Sequence 1: XP_011524725.1
• Gene: AP2S1 / 1175
• HGNCID: 565
• Length: 172
• Species: Homo sapiens
• Sequence 2: NP_536793.1
• Gene: or / 43943
• FlyBaseID: FBgn0003008
• Length: 191
• Species: Drosophila melanogaster
• Alignment Length: 157
• Identity: 58/157 - (36%)
• Similarity: 93/157 - (59%)
• Gaps: 18/157 - (11%)

Human    18 IRFILIQNRAGKTRLAKWYMQFDDDEKQKLIEEVHAVVTVRDAKHTNFVEVLAISVADSLSVLQF 82
            |:.||:.|..||.||:|:|..||:..:|::|:|...:|:.||....||:|        ..|::..
  Fly     2 IKAILVFNNHGKPRLSKFYQYFDESLQQQIIKETFQLVSKRDDNVCNFLE--------GGSLIGG 58

Human    83 RNFKIIYRRYAGLYFCICVDVNDNNLAYLEAIHNFVEVLNEYFHNVCELDLVFNFYKVYTVVDEM 147
            .::|:|||.||.|||..|||.:::.|..|:.|..|||.|::.|.|||||||:|:...|:.::.|:
  Fly    59 SDYKLIYRHYATLYFVFCVDSSESELGILDLIQVFVETLDKCFENVCELDLIFHADAVHHILSEL 123

Human   148 FLAGEIRETS----------QTKVLKQ 164
            .:.|.:.:|:          |.|::||
  Fly   124 VMGGMVLQTNMNDIMARIEEQNKIVKQ 150

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AP2S1	XP_011524725.1	AP2_sigma	18..171	CDD:341437	58/157 (37%)
or	NP_536793.1	AP3_sigma	1..146	CDD:341438	55/151 (36%)