Protein Alignment Hex-t1 and HXK2

DIOPT Version :10

• Sequence 1: NP_788744.1
• Gene: Hex-t1 / 117364
• FlyBaseID: FBgn0042711
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: NP_011261.1
• Gene: HXK2 / 852639
• SGDID: S000003222
• Length: 486
• Species: Saccharomyces cerevisiae
• Alignment Length: 469
• Identity: 126/469 - (26%)
• Similarity: 217/469 - (46%)
• Gaps: 43/469 - (9%)

  Fly     7 PEEDFPEVYKVCKLFNPSIDDLEKIKNAMDREITMGLSRDHHDRSTVPCHLSYVQDLPTGRERGQ 71
            |:|...::....|:|....:.|:.:......|:..|||:...:...:|   .:|.|.|||:|.|.
Yeast    20 PKELMQQIENFEKIFTVPTETLQAVTKHFISELEKGLSKKGGNIPMIP---GWVMDFPTGKESGD 81

  Fly    72 FLALEMMPTNCRIMLVKFSSERDIYTSSKCVIMPHTVAAGRG-TEVFTFLATSIANFVKEK--KV 133
            |||:::..||.|::|||...:|...|:.....:|..:...:. .|::.|:|.|:..|:.|:  :.
Yeast    82 FLAIDLGGTNLRVVLVKLGGDRTFDTTQSKYRLPDAMRTTQNPDELWEFIADSLKAFIDEQFPQG 146

  Fly   134 DKDNLPLGIAFAFTLKKLALDVGILVSWTKEFGAQGAIGKDVVQLLRDALAKFPEISVDVMGIIN 198
            ..:.:|||..|:|...:..::.|||..|||.|........|||.:|:..:.| ..|.::|:.:||
Yeast   147 ISEPIPLGFTFSFPASQNKINEGILQRWTKGFDIPNIENHDVVPMLQKQITK-RNIPIEVVALIN 210

  Fly   199 VGAGSLLALCWAQPDTRIGLIMGSIANSCYVERVERCETYEGDEYRKL---------MIINSDWA 254
            ...|:|:|..:..|:|::|:|.|:..|..|.:.....|..:|    ||         |.||.::.
Yeast   211 DTTGTLVASYYTDPETKMGVIFGTGVNGAYYDVCSDIEKLQG----KLSDDIPPSAPMAINCEYG 271

  Fly   255 HFGDTGQLDFIRNEYDRQLDTESINPGTRIYEKFSGALCMGELVRIIVLRLMKSGAIFAEDRRDY 319
            .| |...:...|.:||..:|.||..||.:.:||.|....:||::|:.::.:.|.|.||.......
Yeast   272 SF-DNEHVVLPRTKYDITIDEESPRPGQQTFEKMSSGYYLGEILRLALMDMYKQGFIFKNQDLSK 335

  Fly   320 IGIQWKLDMVSLIEIVSDPPGVYTKAQEVMDKFRIRH-----CKERDLAALKYICDTVTNRAAML 379
            ....:.:|......|..||   :...::..|.|:...     .:||.|  ::.:.:.:..|||.|
Yeast   336 FDKPFVMDTSYPARIEEDP---FENLEDTDDLFQNEFGINTTVQERKL--IRRLSELIGARAARL 395

  Fly   380 VASGVSCLIDRMRLPQISIAVDGGIYRLHPTFSTVLNKYTRLLAD---------PNYNFEFVITQ 435
            ...|::.:..:.......||.||.:|..:|.|.   .|....|.|         .:|..:.|..:
Yeast   396 SVCGIAAICQKRGYKTGHIAADGSVYNRYPGFK---EKAANALKDIYGWTQTSLDDYPIKIVPAE 457

  Fly   436 DSCGVGAAIMAGMA 449
            |..|.|||::|.:|
Yeast   458 DGSGAGAAVIAALA 471

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hex-t1	NP_788744.1	ASKHA_ATPase-like	24..446	CDD:483947	120/447 (27%)
HXK2	NP_011261.1	ASKHA_NBD_HK1-2_fungi	38..458	CDD:466937	115/436 (26%)