Protein Alignment: CHRNB2 and NtR

• Sequence 1: NP_000739.1
• Gene: CHRNB2
• HGNCID: 1962
• Length: 502
• Species: Homo sapiens
• Sequence 2: NP_651958.2
• Gene: NtR
• FlyBaseID: FBgn0029147
• Length: 585
• Species: Drosophila melanogaster
• Alignment Length: 380
• Identity: 87/381 (23%)
• Similarity: 147/381 (39%)
• Gaps: 79/381 (21%)

Human    29 EERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLT 93
            ||...|.||  |..|.....|:..:.|.::........| :..:...::.|.:.:...|.|.||.
  Fly   212 EETKTEKLL--SHLNIQAENASMPANLSSISFHFQTRSL-AYEQTSSLLQTRMHMMMHWRDSRLV 273

Human    94 WKPEEFDNMKKVRLPSKHIWLPDVVLYNNA-DGM------YEVSFYSNAVVSYDGSIFWLPPAIY 151
            ||||:|.:::....|...||.|.:.:.|.| ..|      ||:..|:|      |||     .:|
  Fly   274 WKPEDFGSLESFEHPDLRIWKPHMNVLNGALQSMGQVLQSYELMVYAN------GSI-----TLY 327

Human   152 KSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVL-------KSEVASLDD------------F 197
              |..:::..:      |....|:|..:|...|:.|       :..||.:.|            .
  Fly   328 --AQNLQLASW------CVDSARNWPSERVTCDIELGLNGQEGQENVALIYDDQRKPIAPNEHVN 384

Human   198 TPSGEWD-------IVALPGRRNENPD---DSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLA 252
            |||| |.       :|....:|..||.   .....|:..:|.::|...||.....:|.:......
  Fly   385 TPSG-WSFTQMSVVLVENDSQRRYNPKGMMQKMTGDVAIEFTLQRNRSFYMTVFYLPLIACQMFL 448

Human   253 ILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVC 317
            ||.|.|.|.  .:.:|.:..||.....|:.:::...|..:. |::..|.:. |:..|:..:..:|
  Fly   449 ILSFVLRST--RRSSLILIALLIAAWGLMYMTRYASPHYVP-PMMTAYKVI-MMTTTYCYILHIC 509

Human   318 VLNVHHRSPTTHTMAP-W-VKVVFLEKLPALL------------FMQQPRHHCAR 358
            ::.:....|  .:.|| | |:|:....|..:|            ..:.|.||.|:
  Fly   510 IIWLDLYPP--RSKAPGWLVRVINSNVLRCILGLRFSDSTDYCDIQENPWHHMAK 562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHRNB2	NP_000739.1	Neur_chan_LBD	29..234	CDD:308532	57/241 (24%)
		Neur_chan_memb	241..478	CDD:308533	28/133 (21%)
NtR	NP_651958.2	Methyltransf_FA	90..191	CDD:289052
		Neur_chan_LBD	212..429	CDD:280998	57/240 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	1	0.900				E1_KOG3645
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100			O	PTHR18945
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.000