Protein Alignment STK38 and wts

DIOPT Version :10

• Sequence 1: NP_009202.1
• Gene: STK38 / 11329
• HGNCID: 17847
• Length: 465
• Species: Homo sapiens
• Sequence 2: NP_733403.1
• Gene: wts / 43651
• FlyBaseID: FBgn0011739
• Length: 1105
• Species: Drosophila melanogaster
• Alignment Length: 490
• Identity: 211/490 - (43%)
• Similarity: 299/490 - (61%)
• Gaps: 54/490 - (11%)

Human     4 TGSTPCSSMS----NHTK---ERVTMT--------------------KVTLENFYSNLIAQHEER 41
            ||:|..||.|    .|..   ||..::                    |..:|....|:|..:.:|
  Fly   607 TGTTASSSTSCKKIKHASPIPERKKISKEKEEERKEFRIRQYSPQAFKFFMEQHIENVIKSYRQR 671

Human    42 EMRQKKLEKVMEEEGLKDEEKRLRRSAHARKETEFLRLKRTRLGLEDFESLKVIGRGAFGEVRLV 106
            ..|:.:|||.|.:.||.|:.:...|....:||:.::||||.::....|..||.||.||||||.||
  Fly   672 TYRKNQLEKEMHKVGLPDQTQIEMRKMLNQKESNYIRLKRAKMDKSMFVKLKPIGVGAFGEVTLV 736

Human   107 QKKDT-GHVYAMKILRKADMLEKEQVGHIRAERDILVEADSLWVVKMFYSFQDKLNLYLIMEFLP 170
            .|.|| .|:||||.|||||:|::.||.|::||||||.|||:.||||::||||||.|||.:|:::|
  Fly   737 SKIDTSNHLYAMKTLRKADVLKRNQVAHVKAERDILAEADNNWVVKLYYSFQDKDNLYFVMDYIP 801

Human   171 GGDMMTLLMKKDTLTEEETQFYIAETVLAIDSIHQLGFIHRDIKPDNLLLDSKGHVKLSDFGLCT 235
            |||:|:||:|.....||..:|||||...|:||:|::|||||||||||:|:|..||:||:||||||
  Fly   802 GGDLMSLLIKLGIFEEELARFYIAEVTCAVDSVHKMGFIHRDIKPDNILIDRDGHIKLTDFGLCT 866

Human   236 GLKKAHRTEFYR-NLNHSLPSDFTFQNMNSKRKAETWKRN---------------RRQLAFSTVG 284
            |.:..|.:::|: |.|||        ..:|....|.:..|               :|.||.|.||
  Fly   867 GFRWTHNSKYYQENGNHS--------RQDSMEPWEEYSENGPKPTVLERRRMRDHQRVLAHSLVG 923

Human   285 TPDYIAPEVFMQTGYNKLCDWWSLGVIMYEMLIGYPPFCSETPQETYKKVMNWKETLTFPPEVPI 349
            ||:||||||..::||.:|||:||:|||:||||:|.|||.:.:|.||.:||:||::||..||:..:
  Fly   924 TPNYIAPEVLERSGYTQLCDYWSVGVILYEMLVGQPPFLANSPLETQQKVINWEKTLHIPPQAEL 988

Human   350 SEKAKDLILRFCCEWEHRIGAPGVEEIKSNSFFEGVDWEHIRERPAAISIEIKSIDDTSNFDEFP 414
            |.:|.|||.|.|...:.|:| ..|:|:||:.||:|:|:..:|::.|....|||...||||||...
  Fly   989 SREATDLIRRLCASADKRLG-KSVDEVKSHDFFKGIDFADMRKQKAPYIPEIKHPTDTSNFDPVD 1052

Human   415 ESDILKPTVATSNHPETDYKNKDW-VFINYTYKRF 448
            ...:.......|:..:.|..::.: .|..:|::||
  Fly  1053 PEKLRSNDSTMSSGDDVDQNDRTFHGFFEFTFRRF 1087

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STK38	NP_009202.1	MobB_NDR1	11..85	CDD:439276	25/100 (25%)
		Interaction with S100B. /evidence=ECO:0000269|PubMed:14661952	62..87		7/24 (29%)
		STKc_NDR1	87..462	CDD:270777	182/380 (48%)
		UFM1-interacting motif (UFIM). /evidence=ECO:0000269|PubMed:32537488	306..311		3/4 (75%)
wts	NP_733403.1	MobB_LATS1	644..718	CDD:439273	20/73 (27%)
		STKc_LATS	717..1078	CDD:270749	178/369 (48%)