Protein Alignment: ATXN2L and Atxn2l

• Sequence 1: XP_005255118.1
• Gene: ATXN2L
• HGNCID: 31326
• Length: 1104
• Species: Homo sapiens
• Sequence 2: XP_006507783.1
• Gene: Atxn2l
• MGIID: 2446242
• Length: 1102
• Species: Mus musculus
• Alignment Length: 1106
• Identity: 1047/1107 (95%)
• Similarity: 1060/1107 (96%)
• Gaps: 6/1107 (1%)

Human     1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65
            ||||||.||.||||||||||||||||.|||||||||||||||..:|||||||||.||||||.|||
Mouse     1 MLKPQPPQQTSQPQQPPPTQQAVARRSPGGTSPPNGGLPGPLTATAAPPGPPAAVSPCLGPAAAA 65

Human    66 GSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNNSRMLHFLTAV 130
            |||||||||.|||...||  ||||||||.||||.|||:|||||||||||||||||||||||||||
Mouse    66 GSGLRRGAESILAASAPP--QHQERPGAVAIGSVRGQTTGKGPPQSPVFEGVYNNSRMLHFLTAV 128

Human   131 VGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIVDTMVFKPSDVMLVHF 195
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||
Mouse   129 VGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIVDTMVFKPSDVLLVHF 193

Human   196 RNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFN 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   194 RNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNGWDPNEMFKFN 258

Human   261 EENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEE 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   259 EENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREIESSPQYRLRIAMENDDGRTEEE 323

Human   326 KHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS 390
            |||||||||||||||||.|||||||||||||||||||||||||||||||||||||||||||||||
Mouse   324 KHSAVQRQGSGRESPSLVSREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS 388

Human   391 SPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAAPPFLPVGRMYPPRS 455
            ||||||||||||||||||||||||||||||||||||||||||.||||..||.|||||||||||||
Mouse   389 SPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGEASVPPTSAALPFLPVGRMYPPRS 453

Human   456 PKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEP 520
            ||||||||:||||||||||||| .|||||||||||.|||.|||||||||:||.|||||||.||||
Mouse   454 PKSAAPAPVSASCPEPPIGSAV-ASSASIPVTSSVVDPGAGSISPASPKLSLTPTDVKELPTKEP 517

Human   521 GRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGK 585
            .|.||.|||||||||||||||||||||||||||||||||||||||||..|||||.||||||.|||
Mouse   518 SRNLEAQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPETGLDPFPSRILKEEAKGK 582

Human   586 EKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGED 650
            ||||||||||:||||||||||||:.|||||.|:|..||||||||.|.||||||||||||||||::
Mouse   583 EKEVDGLLTSDPMGSPVSSKTESILDKEDKVPMAGVGGTEGPEQLPAPCPSQTGSPPVGLIKGDE 647

Human   651 KDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQ 715
            |:||||.||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   648 KEEGPVTEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQ 712

Human   716 YISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQ-AAAA 779
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| ||||
Mouse   713 YISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 777

Human   780 AGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSS 844
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   778 AGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSS 842

Human   845 TPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQQHQAGQAP 909
            |||||:|||||||||||||||||||||||||.|||||||||||||||||||||||| ||||||||
Mouse   843 TPQYPAAEQPTPQALYATVHQSYPHHATQLHGHQPQPATTPTGSQPQSQHAAPSPV-QHQAGQAP 906

Human   910 HLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIH-HQQLPHGFTNMAHVTQA 973
            ||||||||||||||||||||||||||||||||||||||||||||||| |||||||||||||||||
Mouse   907 HLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHPHQQLPHGFTNMAHVTQA 971

Human   974 HVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQ 1038
            |||||:|||||||||||||||||||||||.||||||||||.||||||||||||||||||||||||
Mouse   972 HVQTGVTAAPPPHPGAPHPPQVMLLHPPQGHGGPPQGAVPPSGVPALSASTPSPYPYIGHPQGEQ 1036

Human  1039 PGQAPGFPGGADDRILCRVGRSHSRRRQGLAPGSVLCFPPSSLSCDPAAPLPTASPALSDPDCLL 1103
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse  1037 PGQAPGFPGGADDRILCRVGRSHSRRRQGLAPGSVLCFPPSSLSCDPAAPLPTASPALSDPDCLL 1101

Human  1104 T 1104
            |
Mouse  1102 T 1102

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATXN2L	XP_005255118.1	SM-ATX	122..191	CDD:291131	69/69 (100%)
		PBP1	209..750	CDD:227507	508/541 (94%)
		LsmAD	264..326	CDD:284215	62/62 (100%)
		TFIIA	763..>948	CDD:281188	182/186 (98%)
		TFIIA	882..>1074	CDD:281188	188/193 (97%)
Atxn2l	XP_006507783.1	SM-ATX	120..188	CDD:291131	68/68 (100%)
		LsmAD	262..324	CDD:284215	62/62 (100%)
		TFIIA	880..>1072	CDD:281188	188/193 (97%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C366695019
eggNOG	1	0.900				E1_COG5180
HGNC	1	1.500
Hieranoid	1	1.000
Homologene	1	1.000				H16513
Inparanoid	1	1.050	1976	1.000	Inparanoid score	I1623
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	1	1.010				D147480at33208
OrthoFinder	1	1.000				FOG0001718
OrthoInspector	1	1.000				T2445292
orthoMCL	1	0.900				OOG5_132032
Panther	1	1.100			LDO	PTHR12854
Phylome	1	0.910		0.800	Consistency score
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R2220
TreeFam	1	0.960
	15	15.300