Protein Alignment WIF1 and shf

DIOPT Version :10

• Sequence 1: NP_009122.2
• Gene: WIF1 / 11197
• HGNCID: 18081
• Length: 379
• Species: Homo sapiens
• Sequence 2: NP_001284963.1
• Gene: shf / 31617
• FlyBaseID: FBgn0003390
• Length: 460
• Species: Drosophila melanogaster
• Alignment Length: 342
• Identity: 115/342 - (33%)
• Similarity: 170/342 - (49%)
• Gaps: 40/342 - (11%)

Human    32 QEESLYLWIDAHQARVLI------GFEEDILIVSEGKMAPFTHDFRKAQ-QRMPAIPVNIHSMNF 89
            :|..:.|||:..|.::|.      |:.|.:..:...::   |:|.|... .....||..::.:||
  Fly   113 EESGISLWINEQQLKMLTALYFPQGYSERLYAIHNSRV---TNDLRDTTLYNFLVIPSEVNYVNF 174

Human    90 TWQAAGQAEYFYEFLSLRSLDKGIMADPTVNVPLLGTVPHKASVVQVGFPCLGKQDGVAAFEVDV 154
            ||: :|:.:|||:|..|:::|:.|:..||:::...|.:|.:.....:..||.|...|.|:|.|.:
  Fly   175 TWK-SGRRKYFYDFDRLQTMDESILKAPTLSIRKSGRIPQEQKNFSIFLPCTGNSSGTASFNVGL 238

Human   155 IVMNSEGNTILQTPQNAIFFKTCQ------------------QA---ECPGGCRNGGFCNERRIC 198
            .:.......:..||....|.|.|.                  ||   ||...|...|:|||..||
  Fly   239 KIQTRHNKPLSGTPIRLNFKKECAHRGVYDIDASNPTSLTTLQAPDPECSLKCGKNGYCNEHHIC 303

Human   199 ECPDGFHGPHCEKALCTPRCMNGGLCVTPGFCICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCI 263
            :|..|:.|.:||.|.|.|:|:|||.|..|..|.||.|:.|..|:...|...|.|||.|....||.
  Fly   304 KCNVGYTGQYCETAFCFPQCLNGGNCTAPSVCTCPEGYQGTQCEGGICKDKCLNGGKCIQKDKCQ 368

Human   264 CPPGLEGEQCEISKCPQPCRNGGKCIGKSKCKCSKGYQGDLC-----SKPVCEPGCGAHGTCHEP 323
            |..|..|.:||.|||..||:|.|:|||.:.|:|..|.:||.|     .:.:|:  | .:|||...
  Fly   369 CSKGYYGLRCEYSKCVIPCKNEGRCIGNNLCRCPNGLRGDHCEIGRKQRSICK--C-RNGTCVSH 430

Human   324 NKCQCQEGWHGRHCNKR 340
            ..|:|..|::|||||.|
  Fly   431 KHCKCHPGFYGRHCNGR 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
WIF1	NP_009122.2	WIF	35..179	CDD:128745	40/168 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	354..379
shf	NP_001284963.1	WIF	120..258	CDD:470637	36/141 (26%)