Protein Alignment AKR1C4 and CG2767

DIOPT Version :9

• Sequence 1: NP_001809.4
• Gene: AKR1C4 / 1109
• HGNCID: 387
• Length: 323
• Species: Homo sapiens
• Sequence 2: NP_649757.1
• Gene: CG2767 / 40946
• FlyBaseID: FBgn0037537
• Length: 329
• Species: Drosophila melanogaster
• Alignment Length: 325
• Identity: 121/325 - (37%)
• Similarity: 192/325 - (59%)
• Gaps: 19/325 - (5%)

Human    11 NDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIRSKIADGSVK 75
            |:|..|||:|.||:...:.....|::.   |:|||:||||:|.:|.||:.:|..::..:..|.||
  Fly    10 NNGEKMPVIGIGTWQASDEEIETAIDA---ALEAGYRHIDTAPVYGNEKAIGRVLKRWLDAGKVK 71

Human    76 REDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPLPK-DENGKVIF 139
            ||::|..:|:.....:|..|:|.::.||:.||||||||||:|.|..:...|....| |:.|.:..
  Fly    72 REELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININEDGSFKLDKEGLMEV 136

Human   140 D-TVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLL 203
            | |.:.:|.|..||...:.||.||||||||:..|:..:|.  ..|.:|..||:|.|.||.|..|:
  Fly   137 DVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLK--NCKIRPANNQIEHHVYLQQRDLV 199

Human   204 DFCKSKDIVLVAHSALGTQ-----RHKLWVDPNSPVLLEDPVLCALAKKHKQTPALIALRYQLQR 263
            |||||::|.:.|:|.||::     .....:..:.|.|::.|.:..:|..|.:|||.:.||:.:..
  Fly   200 DFCKSENITVTAYSPLGSKGIAKFNAGAGIVRDLPDLMDIPEVKEIAASHGKTPAQVLLRWIIDT 264

Human   264 GVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYVVMDF-----LMDHPDYPFSDEY 323
            ||..:.||.|..|:::|:.||:|:||:|::..|..|::|.|  :.||     :..||::.|.::|
  Fly   265 GVSAIPKSTNPARLKQNLDVFDFELTAEEVAKLSSLDQNIR--ICDFAFFHGVERHPEFTFKNQY 327

Human   324  323
              Fly   328  327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AKR1C4	NP_001809.4	AKR_AKR1C1-35	6..306	CDD:381334	115/301 (38%)
CG2767	NP_649757.1	ARA1	5..302	CDD:223729	113/296 (38%)
		Tas	10..297	CDD:223739	111/291 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.830