Protein Alignment: NPFFR2 and RYa-R

• Sequence 1: NP_004876.2
• Gene: NPFFR2
• HGNCID: 4525
• Length: 522
• Species: Homo sapiens
• Sequence 2: NP_001287552.1
• Gene: RYa-R
• FlyBaseID: FBgn0004842
• Length: 518
• Species: Drosophila melanogaster
• Alignment Length: 365
• Identity: 117/366 (32%)
• Similarity: 180/366 (49%)
• Gaps: 47/366 (13%)

Human   151 IISYFL---IFFLCMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAG 212
            ||.|.|   ||...::||..||:||.....|.||||.||.:|||.|:|:..||:|.:.:...|..
  Fly   106 IIVYMLYIPIFIFALIGNGTVCYIVYSTPRMRTVTNYFIASLAIGDILMSFFCVPSSFISLFILN 170

Human   213 -WPFGNTMCKISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITI 276
             ||||..:|......|.:||..|.:|||||::||:..:::|.||::|.:.|..||..:|.:|:..
  Fly   171 YWPFGLALCHFVNYSQAVSVLVSAYTLVAISIDRYIAIMWPLKPRITKRYATFIIAGVWFIALAT 235

Human   277 MSPSAVM---------LHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLA 332
            ..|..::         .|.:.|||.               |||.||::.....||..|||..::.
  Fly   236 ALPIPIVSGLDIPMSPWHTKCEKYI---------------CREMWPSRTQEYYYTLSLFALQFVV 285

Human   333 PLSLIVIMYGRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMM 397
            ||.:::..|.||.|.::....|.....|::|  .::|.|:|::||:|.|.::|...|||...|.:
  Fly   286 PLGVLIFTYARITIRVWAKRPPGEAETNRDQ--RMARSKRKMVKMMLTVVIVFTCCWLPFNILQL 348

Human   398 L---SDYADLSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQKRA 459
            |   .::|...|..      |::...||||..:...|||||.:.|..||.||     :||..:..
  Fly   349 LLNDEEFAHWDPLP------YVWFAFHWLAMSHCCYNPIIYCYMNARFRSGF-----VQLMHRMP 402

Human   460 KPMEAYALKAKSHVLINTSNQLVQESTFQNPHGETLLYRK 499
            .......|::....:..||.::   :|..:.|....|:||
  Fly   403 GLRRWCCLRSVGDRMNATSGEM---TTKYHRHVGDALFRK 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFFR2	NP_004876.2	7tm_4	155..>277	CDD:304433	50/126 (40%)
		7tm_1	164..435	CDD:278431	95/284 (33%)
RYa-R	NP_001287552.1	7tm_4	113..>234	CDD:304433	49/121 (40%)
		7tm_1	122..383	CDD:278431	95/284 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000				FOG0000759
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R3897
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.030