Protein Alignment: NPFFR2 and NPFR

• Sequence 1: NP_004876.2
• Gene: NPFFR2
• HGNCID: 4525
• Length: 522
• Species: Homo sapiens
• Sequence 2: NP_001246947.1
• Gene: NPFR
• FlyBaseID: FBgn0037408
• Length: 489
• Species: Drosophila melanogaster
• Alignment Length: 378
• Identity: 108/379 (28%)
• Similarity: 185/379 (49%)
• Gaps: 60/379 (16%)

Human   116 HPIWNVN-DTKHHL------YSDINIT--------YVNYYLHQPQVAA----IFIISYFLIFFLC 161
            ||:..:: .|.|.|      .||:|.|        .::.:|....|.:    :.|..|.::....
  Fly    36 HPLDYLDLGTVHALNTTAINTSDLNETGSRPLDPVLIDRFLSNRAVDSPWYHMLISMYGVLIVFG 100

Human   162 MMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFG--NTMCKISG 224
            .:|||:|...|:|...|.|..|||||||||||||:.:..||:||::.:...||:|  :.:||...
  Fly   101 ALGNTLVVIAVIRKPIMRTARNLFILNLAISDLLLCLVTMPLTLMEILSKYWPYGSCSILCKTIA 165

Human   225 LVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPSAVMLHVQEE 289
            ::|.:.:..|..::.|||.||:|.:|||.:..|....|..|:..||.||:.:.||..|
  Fly   166 MLQALCIFVSTISITAIAFDRYQVIVYPTRDSLQFVGAVTILAGIWALALLLASPLFV------- 223

Human   290 KYYRVRLNSQNKT--------SPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIMY----- 341
              |:..:|:....        ..:.:|.||||::..|..|:.......||.|:.::.:.|
  Fly   224 --YKELINTDTPALLQQIGLQDTIPYCIEDWPSRNGRFYYSIFSLCVQYLVPILIVSVAYFGIYN 286

Human   342 ---GRIGISLFRAAVPHTGRKNQEQWHVVSRKKQKIIKMLLIVALLFILSWLPLWTLMMLSDYAD 403
               .||.:...:|:   :.::..|:    .|:.::...:|:.:|::|.:||||   |...:.|||
  Fly   287 KLKSRITVVAVQAS---SAQRKVER----GRRMKRTNCLLISIAIIFGVSWLP---LNFFNLYAD 341

Human   404 LSPNELQIINIYIYPFAHWLAFGNSSVNPIIYGFFNENFRRGFQEAFQLQLCQ 456
            :..:.:....:..|...|.:...::..||::||:.|:|||:.|||.    ||:
  Fly   342 MERSPVTQSMLVRYAICHMIGMSSACSNPLLYGWLNDNFRKEFQEL----LCR 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPFFR2	NP_004876.2	7tm_4	155..>277	CDD:304433	48/124 (39%)
		7tm_1	164..435	CDD:278431	84/289 (29%)
NPFR	NP_001246947.1	7tm_4	98..>195	CDD:304433	41/97 (42%)
		7tm_1	103..373	CDD:278431	84/289 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030		avgDist	Average_Evolutionary_Distance	R3897
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.030