Protein Alignment HYOU1 and CG7182

DIOPT Version :10

• Sequence 1: NP_001397970.1
• Gene: HYOU1 / 10525
• HGNCID: 16931
• Length: 1000
• Species: Homo sapiens
• Sequence 2: NP_648212.1
• Gene: CG7182 / 38944
• FlyBaseID: FBgn0035878
• Length: 513
• Species: Drosophila melanogaster
• Alignment Length: 454
• Identity: 101/454 - (22%)
• Similarity: 186/454 - (40%)
• Gaps: 96/454 - (21%)

Human    38 VDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKNPKATLRYFQH 102
            :.:|:.::.:|.|:.....|::.||:..|.:...:        ..|.|:.:     :..|...|
  Fly     7 IKIGNSTLCIAHVRADGKAEVIANKQGDRVSQACL--------LWDGASEI-----ECGLTAKQ- 57

Human   103 LLGKQADNPHVAL---YQARFPEHELT--------------FDPQRQTVHFQISSQLQFSPE--- 147
               |.|:.|..|:   :|...|:.|||              ||  ::.:.|::...:....|
  Fly    58 ---KMANRPRQAVAHSFQLLQPKEELTEEKLSSALREIPCDFD--KEELVFRMEHTVPSDREDQD 117

Human   148 ---------------EVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGL 197
                           |:|...|..:.....|..:.||  ||:::|.::..:..:.:..||:.||.
  Fly   118 DRVVTKDLSAYQVTVELLRAELELAHQYHTDGEQAPI--AVLSIPSYYPASAYKLLADAAQTAGF 180

Human   198 KVLQLINDNTATALSYGV-----FRRKDINTTA-----QNIMFYDMGSGSTVCTIVTYQMVKTKE 252
            .|.|:|.:.||..|.|.:     .:|:.:.|..     .:|.||.:.:|..| .:.|:
  Fly   181 HVAQIITEPTAAVLGYSIGEEQTEQRRHVLTIKCGGLYSDIAFYSVQNGLFV-QLATF------- 237

Human   253 AGMQPQLQIRGVGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLK 317
             |..|            :||.:    ..|.|.....|:.:.:...|..|:.|::||:...|...|
  Fly   238 -GPFP------------IGGRQ----FTEALVQFICEEFRRKYKLDPHESRRSVAKIRTAAANCK 285

Human   318 TVLSANADHMAQIEGLMDDVDFKAKVTRVEFEELCA----DLFERVPGPVQQALQSAEMSLDEIE 378
            .:|:........|:.|||.||:.|:::|..||.|..    :|.:::...|:|| |.....|.:|:
  Fly   286 HILTTMPSTQLYIDSLMDGVDYNAQMSRARFESLIQPVINNLIQQLGECVEQA-QKEHPGLSKID 349

Human   379 QVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVV 442
            .::|:|...::|::|..:.......:|..:.:|||..|:|...||..|....:.:.....|.||
  Fly   350 DIVLLGATMQIPKLQAAVGARFPDAKLHNSHSADEVVAIGCARQAVCLIDPLEQQLHKEEDCVV 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HYOU1	NP_001397970.1	ASKHA_NBD_HSP70_HYOU1	34..424	CDD:466828	96/434 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	578..694
		LGT	<593..694	CDD:469786
		Prevents secretion from ER. /evidence=ECO:0000255	997..1000
CG7182	NP_648212.1	ASKHA_ATPase-like	5..394	CDD:483947	95/433 (22%)