DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment: CDK7 and CG6800

Sequence 1:NP_001790.1 Gene:CDK7 HGNCID:1778 Length:346 Species:Homo sapiens
Sequence 2:NP_650984.1 Gene:CG6800 FlyBaseID:FBgn0038902 Length:302 Species:Drosophila melanogaster

Alignment Length:283 Identity:110/284 (39%)
Similarity:171/284 (60%) Gaps:8/284 (3%)


Human    11 RYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSHPNII 75
            ||:.|:.:|||....|:||.|...|:.|||||:.|.::.   ..|....|||||.||......|:
  Fly     8 RYKMLEKIGEGVHGCVFKAIDLQRNKEVAIKKVALKNKF---GNIALNTLREIKTLQLCKSEYIL 69

Human    76 GLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLHQHWILHRDLKP 140
            .::|.:...:.:|||.::....|...:|.....|:...::.:.....:|:.|||:..::|||:||
  Fly    70 DIIDIYPDLTGLSLVLEYQPDTLYNRLKSEVNPLSRQQVRKFAHQMFKGIAYLHEAGLMHRDIKP 134

Human   141 NNLLLDENGVLKLADFGLAKSF--GSPNRAYTHQVVTRWYRAPELLFGARMYGVGVDMWAVGCIL 203
            .|||:.:..:||:||||||:.:  ...:|.|:.||.||||||||:|||::.||.||||||.||::
  Fly   135 ANLLISDTDMLKIADFGLARLYFPEDESRLYSPQVSTRWYRAPEILFGSQKYGTGVDMWAAGCVV 199

Human   204 AELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDY--VTFKSFPGIPLHHIFSAAGD 266
            ||:|..||...|.:|::||..|..|||:|...|||::.|||||  :.|.:..||...::|.:...
  Fly   200 AEMLRGVPLFAGTTDIEQLAIIIRTLGSPRLNQWPELTSLPDYSKIRFPNSVGIHWDNLFPSCTH 264

Human   267 DL-LDLIQGLFLFNPCARITATQ 288
            .: ::|:..|.::||..|:.|::
  Fly   265 AVEINLVSNLVVYNPKNRLKASE 287

Known Domains:


GeneSequenceDomainRegion External IDIdentity
CDK7NP_001790.1 STKc_CDK7 11..308 CDD:270833 110/284 (39%)
CG6800NP_650984.1 STKc_CCRK 8..295 CDD:270826 110/284 (39%)
S_TKc 9..288 CDD:214567 109/283 (39%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_KOG0659
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 D1367115at2759
OrthoFinder 1 1.000 FOG0001496
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.910

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