DIOPT Ortholog Finder



Part of the DRSC/TRiP Functional Genomics Tools

DIOPT - DRSC Integrative Ortholog Prediction Tool

Version 10.0 (Nov 2025)
Details of this tool are published in Hu, et. al.

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Your 1 query symbols mapped to 1 genes.


Input OrderSearch TermFly GeneIDFlyBaseIDFly SymbolSpecies 2Human GeneIDHuman Species Gene IDHuman SymbolEnsmbl ID
(link HPA)		DIOPT ScoreWeighted ScoreRankBest ScoreBest Score ReversePrediction Derived FromAlignment & ScoresFeedbackGene
Details
1 FBgn0003731 37455 FBgn0003731 Egfr Human 2066 3432 ERBB4 ENSG00000178568 13 12.81 high Yes Yes Domainoid, eggNOG, Inparanoid, OMA, OrthoDB, OrthoFinder, OrthoInspector, Compara, Hieranoid, Panther, Phylome, SonicParanoid, orthoMCL
Add G2F details (ERBB4)

DRscDB Data: (ERBB4)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 2064 3430 ERBB2 ENSG00000141736 12 11.88 moderate No Yes Domainoid, eggNOG, Inparanoid, OMA, OrthoDB, OrthoFinder, OrthoInspector, Hieranoid, Panther, Phylome, SonicParanoid, orthoMCL
Add G2F details (ERBB2)

DRscDB Data: (ERBB2)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 1956 3236 EGFR ENSG00000146648 12 11.88 moderate No Yes Domainoid, eggNOG, Inparanoid, OMA, OrthoDB, OrthoFinder, OrthoInspector, Hieranoid, Panther, Phylome, SonicParanoid, orthoMCL
Add G2F details (EGFR)

DRscDB Data: (EGFR)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 2065 3431 ERBB3 ENSG00000065361 11 10.87 moderate No Yes Domainoid, eggNOG, Inparanoid, OrthoDB, OrthoInspector, Hieranoid, OrthoFinder, Panther, Phylome, SonicParanoid, orthoMCL
Add G2F details (ERBB3)

DRscDB Data: (ERBB3)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 7301 12446 TYRO3 ENSG00000092445 1 0.93 low No Yes Compara
Add G2F details (TYRO3)

DRscDB Data: (TYRO3)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 7010 11724 TEK ENSG00000120156 1 0.93 low No No Compara
Add G2F details (TEK)

DRscDB Data: (TEK)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 2042 3387 EPHA3 ENSG00000044524 1 0.93 low No No Compara
Add G2F details (EPHA3)

DRscDB Data: (EPHA3)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 3791 6307 KDR ENSG00000128052 1 0.93 low No No Compara
Add G2F details (KDR)

DRscDB Data: (KDR)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 2043 3388 EPHA4 ENSG00000116106 1 0.93 low No No Compara
Add G2F details (EPHA4)

DRscDB Data: (EPHA4)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 4916 8033 NTRK3 ENSG00000140538 1 0.93 low No No Compara
Add G2F details (NTRK3)

DRscDB Data: (NTRK3)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 2047 3392 EPHB1 ENSG00000154928 1 0.93 low No No Compara
Add G2F details (EPHB1)

DRscDB Data: (EPHB1)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 10461 7027 MERTK ENSG00000153208 1 0.93 low No Yes Compara
Add G2F details (MERTK)

DRscDB Data: (MERTK)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 5156 8803 PDGFRA ENSG00000134853 1 0.93 low No No Compara
Add G2F details (PDGFRA)

DRscDB Data: (PDGFRA)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 2322 3765 FLT3 ENSG00000122025 1 0.93 low No No Compara
Add G2F details (FLT3)

DRscDB Data: (FLT3)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 780 2730 DDR1 ENSG00000204580 1 0.93 low No No Compara
Add G2F details (DDR1)

DRscDB Data: (DDR1)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 3480 5465 IGF1R ENSG00000140443 1 0.93 low No No Compara
Add G2F details (IGF1R)

DRscDB Data: (IGF1R)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 2048 3393 EPHB2 ENSG00000133216 1 0.93 low No No Compara
Add G2F details (EPHB2)

DRscDB Data: (EPHB2)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 2051 3396 EPHB6 ENSG00000106123 1 0.93 low No No Compara
Add G2F details (EPHB6)

DRscDB Data: (EPHB6)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 2050 3395 EPHB4 ENSG00000196411 1 0.93 low No No Compara
Add G2F details (EPHB4)

DRscDB Data: (EPHB4)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 4233 7029 MET ENSG00000105976 1 0.93 low No No Compara
Add G2F details (MET)

DRscDB Data: (MET)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 3815 6342 KIT ENSG00000157404 1 0.93 low No No Compara
Add G2F details (KIT)

DRscDB Data: (KIT)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 5159 8804 PDGFRB ENSG00000113721 1 0.93 low No No Compara
Add G2F details (PDGFRB)

DRscDB Data: (PDGFRB)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 2046 3391 EPHA8 ENSG00000070886 1 0.93 low No No Compara
Add G2F details (EPHA8)

DRscDB Data: (EPHA8)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 2049 3394 EPHB3 ENSG00000182580 1 0.93 low No No Compara
Add G2F details (EPHB3)

DRscDB Data: (EPHB3)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 4920 10257 ROR2 ENSG00000169071 1 0.93 low No No Compara
Add G2F details (ROR2)

DRscDB Data: (ROR2)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 4914 8031 NTRK1 ENSG00000198400 1 0.93 low No No Compara
Add G2F details (NTRK1)

DRscDB Data: (NTRK1)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 2044 3389 EPHA5 ENSG00000145242 1 0.93 low No No Compara
Add G2F details (EPHA5)

DRscDB Data: (EPHA5)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 4919 10256 ROR1 ENSG00000185483 1 0.93 low No No Compara
Add G2F details (ROR1)

DRscDB Data: (ROR1)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 2041 3385 EPHA1 ENSG00000146904 1 0.93 low No No Compara
Add G2F details (EPHA1)

DRscDB Data: (EPHA1)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 238 427 ALK ENSG00000171094 1 0.93 low No No Compara
Add G2F details (ALK)

DRscDB Data: (ALK)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 284656 19987 EPHA10 ENSG00000183317 1 0.93 low No No Compara
Add G2F details (EPHA10)

DRscDB Data: (EPHA10)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 1969 3386 EPHA2 ENSG00000142627 1 0.93 low No No Compara
Add G2F details (EPHA2)

DRscDB Data: (EPHA2)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 4486 7381 MST1R ENSG00000164078 1 0.93 low No No Compara
Add G2F details (MST1R)

DRscDB Data: (MST1R)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 2321 3763 FLT1 ENSG00000102755 1 0.93 low No No Compara
Add G2F details (FLT1)

DRscDB Data: (FLT1)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 3645 6093 INSRR ENSG00000027644 1 0.93 low No No Compara
Add G2F details (INSRR)

DRscDB Data: (INSRR)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 4058 6721 LTK ENSG00000062524 1 0.93 low No No Compara
Add G2F details (LTK)

DRscDB Data: (LTK)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 2045 3390 EPHA7 ENSG00000135333 1 0.93 low No No Compara
Add G2F details (EPHA7)

DRscDB Data: (EPHA7)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 4915 8032 NTRK2 ENSG00000148053 1 0.93 low No No Compara
Add G2F details (NTRK2)

DRscDB Data: (NTRK2)

Human Protein
Atlas
(HPA)
1 FBgn0003731 37455 FBgn0003731 Egfr Human 1436 2433 CSF1R ENSG00000182578 1 0.93 low No No Compara
Add G2F details (CSF1R)

DRscDB Data: (CSF1R)

Human Protein
Atlas
(HPA)

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