:root {
    --first_border_radius: 2px;
    --custom-bs-gradient: linear-gradient(180deg, rgba(255, 255, 255, 0.15), rgba(255, 255, 255, 0));
    /*--primary_background_color: rgba(var(--bs-light-rgb), 1); */
    --custom-bs-bg-opacity: 1;
    --custom-bs-light-rgb: 13,110,253;
    --primary_background_color: rgba(var(--bs-light-rgb), var(--custom-bs-bg-opacity));
    --primary-background-image: var(--custom-bs-gradient);

    --active-color: rgba(125, 125, 125, 1);
}


.top_content {
    display: flex;
    flex-direction: column;
    justify-content: center;
    align-items: center;
}
.top_content div {
    display: flex;
    flex-direction: row;
    justify-content: center;
    align-items: center;
}

#content_overarching {
    padding-bottom: 60px;
}

#nav_bar {
  background-color: #000000;
	color: #000;
	position: sticky; top: 0;
	z-index: 1000;
  align-items: center;
}

.loading .main_content {
    display: none;
}
    
.loading .loading_message {
    display: flex;
    flex-direction: column;
    justify-content: center;
    align-items: center;
}
    
.loading_message {
    display: none;
}
.main_content {
    display: block;
    width: 100%;
    height: auto;
}
    
.spinner {
  width: 40px;
  height: 40px;
  border: 4px solid #f3f3f3;
  border-top: 4px solid #3498db;
  border-radius: 50%;
  animation: spin 1s linear infinite;
  margin: 20px auto;
}
@keyframes spin {
  0%   { transform: rotate(0deg); }
  100% { transform: rotate(360deg); }
}


.btn {
    border-radius: var(--first_border_radius) !important;
}

.custom_buttons {
    border-radius: var(--first_border_radius) !important;
    border-width: var(--bs-border-width) !important;
    border-color: rgba(0, 0, 0, 0.3);
    color: inherit;
    padding: 7px 12px;
}

.custom_buttons:hover {
    border-color: rgba(0, 0, 0, 1);
}

.custom_buttons:active {
    color: rgb(100, 100, 100) !important;
}

.dt-button {
    border-radius: var(--first_border_radius) !important;
    border-width: var(--bs-border-width) !important;
    border-color: rgba(0, 0, 0, 0.3) !important;
    color: inherit !important;
}

.dt-button:hover {
    border-radius: var(--first_border_radius) !important;
    border-width: var(--bs-border-width) !important;
    border-color: rgba(0, 0, 0, 1) !important;
    color: inherit !important;
}

.dt-info {
    color: var(--primary_background_color) !important;
}

.dt-search label {
    color: var(--primary_background_color) !important;
}

.dt-paging-button {
    border-radius: var(--first_border_radius) !important;
    border-width: var(--bs-border-width) !important;
    border-color: rgba(0, 0, 0, 0.3) !important;
    color: inherit !important;
}

.dt-paging-button:hover {
    border-color: rgba(0, 0, 0, 1) !important;
}

.dt-length {
    padding-right: 10px;
}
.dt-length select {
    background-color: var(--primary_background_color) !important;
}

.dt-length label {
    color: var(--primary_background_color) !important;
}

#list_analysis_summary_div .dt-length label {
    color: inherit !important;
}

#list_analysis_summary_div .dt-info label {
    color: inherit !important;
}

#receptor_rank_filter .is-selected {
    background-color: var(--active-color) !important;
}

.hms_logo {
  display: flex;
	margin: 0;
	height: 50px;
}

.nav_link {
  color: white;
}

.nav_link:hover {
  color: grey;
}

.nav_menu {
  display: flex;
  flex-direction: row;
	justify-content: space-between;
  /*align-items: center; */
}

.footer {
  background-color: lightgray;
  bottom: 0;
  position: fixed;
  width: 100%;
  font-size: 14px;
  z-index: 9999;
}

.overarching {
  align-items: center;
}

#listAnalysis {
  resize: none;
}

.gene_search_columns dl {
  display: grid;
  grid-template-columns: max-content auto;
  row-gap: 0;
  column-gap: 1em;
}

.gene_search_columns dt {
  font-weight: bold;
  margin: 0;
  padding: 0 0.2em 0 0;
  text-align: right;
}

.gene_search_columns dd {
  margin: 0 0 0.4em 0;
  padding: 0;
}

.dt-button-collection {
  max-height: 300px;
  overflow-y: auto;
}

#query_builder {
    display: flex;
    justify-content: center;
    align-content: center;
    gap: 0.5rem;
}

#tissue_specificity_dropdowns {
    display: flex;
    flex-direction: column;
    justify-content: center;
}

#dropdown_list {
    max-height: 300px;
    overflow-y: auto;
}

#query_form_div {
    display: flex;
    justify-content: center;
    align-items: center;
}
.list_analysis_buttons {
    background-color: white;
}

.list_analysis_tables{
    font-size: 9px;
}

#bulk_rna_seq_table {
    border: 2px;
    border-radius: 5px;
}

#original_bulk_seq {
    font-size: 8px;
}

.heatmap_horizontal_container {
    overflow-x: scroll;
    display: block;
}

.heatmap_vertical_container {
    overflow-y: auto;
    display: block;
}

#proteomics_display_info_container {
    border-radius: 8px;
}

#proteomics_display_info {
    text-align: left;
}

#ortholog_buttons {
    display: flex;
    flex-direction: row;
    justify-content: center;
    align-items: center;
    gap: 5%;
}

#orthologs_filter_div {
    background: rgba(255, 0, 0, 0.1);
}

#ortholog_sources_filter_div div {
    display: flex;
    flex-direction: column;
    justify-content: center;
    align-items: center;
    gap: 2%;
}



.v-lines th,
.v-lines td {
  border-left: 1px solid grey;
  border-right: 1px solid grey;
}


.v-lines td:empty {
  border: none;
  padding: 0;
  margin: 0;
}

.dt_container {
    display: flex;
    justify-content: center;
    overflow-x: scroll;
}

/*
.containers_container {
    display: flex;
    justify-content: center;
    display: block;
}
*/

.containers_container {
  overflow-x: auto;    /* enable horizontal scrolling here */
  max-width: 100%;     /* don’t grow wider than its parent */
}



.heatmap_horizontal_tables {
    width: auto !important;
}

.header_img_container {
    display: flex;
     justify-content: center;
     align-items: center;
     width: 100%;
}

#index_header {
  margin: 0;
}

.header-spacer {
  width: 40px;    /* roughly match the logo width */
}

.fly_secretome_logo {
    margin-right: 0.5em;
}

#indexFormContainer {
    /*background-color: grey; */
    width: 100%;
    border-radius: 8px;
    padding: 2%;
    display: flex;
    flex-direction: column;
    justify-content: center;
    align-items: center;
}

.indexImages {
    /*height: 90px;
    width: 90px; */
    height: 6%;
    width: 6%;
    margin-right: 0.7%;
    margin-left: 0.7%;
}

.indexForms {
    display: flex;
    flex-direction: row;
    background-color: darkgray;
    border-radius: 8px;
    padding: 2%;
    width: 60%;
    justify-content: space-between;
    align-items: center;
}

.formInputDiv {
    display: flex;
    flex-direction: column;
    align-items: center;
    justify-content: center;
    padding: 2%;
    gap: 10px;
}

.indexFormOptionInfo {
    font-size: 11px;
}

.formTitleDiv {
    background-color: rgba(248, 249, 250, var(--bs-bg-opacity));
    background-image: var(--bs-gradient);
    border-radius: 8px;
    padding: 2%;
}



div.dt-button-collection {
    max-height: 300px;
    overflow-y: auto !important;
    overflow-x: hidden;
    width: auto !important;
}

#ortholog_table_container_ls_html .dt-buttons {
    display: flex;
    flex-direction: column;
    justify-content: center;
    align-items: center;

}


.dt-button {
    background-color: var(--bs-secondary-bg) !important;
}

.dt-paging-button {
    background-color: var(--bs-secondary-bg) !important;
}