DRSC/TRiP Functional Genomics Resources

Multi Sequence Alignment :

Domains

Index TaxID Gene Name GeneID Protein ID Domain
start 		Domain
stop 		Domain
name 		Domain
description 		external_id
hs 9606 NUDT10 170685 NP_694853.1 144 164 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite propagated from UniProtKB/Swiss-Prot (Q8NFP7.1)
hs 9606 NUDT10 170685 NP_694853.1 50 71 Nudix box propagated from UniProtKB/Swiss-Prot (Q8NFP7.1)
hs 9606 NUDT10 170685 NP_694853.1 18 143 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
mm 10090 Nudt10 102954 NP_001026834.1 144 164 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite propagated from UniProtKB/Swiss-Prot (P0C027.1)
mm 10090 Nudt10 102954 NP_001026834.1 50 71 Nudix box propagated from UniProtKB/Swiss-Prot (P0C027.1)
mm 10090 Nudt10 102954 NP_001026834.1 18 143 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
mm 10090 Nudt11 58242 NP_067406.2 144 164 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite propagated from UniProtKB/Swiss-Prot (P0C028.1)
mm 10090 Nudt11 58242 NP_067406.2 50 71 Nudix box propagated from UniProtKB/Swiss-Prot (P0C028.1)
mm 10090 Nudt11 58242 NP_067406.2 18 143 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
rn 10116 Nudt11 680248 NP_001388133.1 18 143 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
xt 8364 nudt4 448180 NP_001005679.1 19 143 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
dr 7955 nudt4a 378990 NP_001296990.1 62 187 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
dr 7955 nudt4b 447910 NP_001004648.1 18 143 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
dm 7227 Aps 39226 NP_648421.1 19 143 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
ag 7165 Aps 1279315 XP_061514530.1 - - - - -
ce 6239 Y92H12BL.5 259365 NP_740784.1 26 146 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
is 6945 Aps 8034888 XP_002410734.1 18 127 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
sc 4932 DDP1 854334 NP_014806.1 33 181 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
sp 4896 aps1 2542890 NP_592840.1 45 203 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
at 3702 NUDT16 820440 NP_566428.1 21 158 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
at 3702 NUDX13 822281 NP_189303.1 21 166 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
at 3702 NUDT12 837845 NP_563919.1 21 165 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
at 3702 NUDT17 814696 NP_565273.1 26 157 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
at 3702 NUDT18 838051 NP_172939.1 21 152 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
at 3702 NUDT4 838410 NP_173266.1 61 193 NUDIX_DIPP2_like_Nudt4 diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase type 2 and similar proteins; cd04666 CDD:467551
ec 83333 nudE 947906 NP_417856.1 1 184 nudE adenosine nucleotide hydrolase NudE; Provisional; PRK11762 CDD:183303
ec 83333 nudK 947072 NP_416962.1 1 191 PRK15009 GDP-mannose pyrophosphatase NudK; Provisional CDD:184971
ec 83333 rppH 947300 NP_417307.1 1 156 PRK00714 RNA pyrophosphohydrolase; Reviewed CDD:234820
ec 83333 nudF 947519 NP_417506.1 9 209 nudF ADP-ribose pyrophosphatase NudF; Provisional; PRK10729 CDD:182682
ec 83333 nudB 946383 NP_416379.1 4 150 nudB dihydroneopterin triphosphate pyrophosphatase; Provisional; PRK09438 CDD:236516

Highlight Region

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Alignment

Alignment done with MAFFT FFT-NS-2 (v7.305b) aligner. MAFFT References

Download raw alignment output file

Download fasta input file



Note:   &mbsp 2019, we've been having trouble with some alignments and are looking into the problem. If the alignment didn't work, please try again. If it still doesn't work, please download the fasta file and align off line. We're looking into it. Thanks.

hs  --------------------------------------------------------------------------------------MKCKPNQTRTYDP--------EGFKKRAACLCF- [25]
mm  --------------------------------------------------------------------------------------MKCKPNQTRTYDP--------EGFKKRAACLCF- [25]
mm6 --------------------------------------------------------------------------------------MKCKPNQTRTYDP--------EGFKKRAACLCF- [25]
rn  --------------------------------------------------------------------------------------MKCKPNQTRTYDP--------EGFKKRAACLCF- [25]
xt  -------------------------------------------------------------------------------------MMKFKPNQTRTYDR--------EGFKKRAACLCF- [26]
dr  ------------------------------------------MISLGNLGRLSALGLKGSCVARRIQKLGNREHLYSCFVRRKTHMMKFKPNQTRTYDG--------EGFKKRAACLCF- [69]
dr6 --------------------------------------------------------------------------------------MKFKPNQTRTYDR--------EGFKRRAACLCF- [25]
dm  -------------------------------------------------------------------------------------MVKEKPNSTRIYDK--------DGFRRRAACICV- [26]
ag  -------------------------------------------------------------------------------------MVKEKPNSIRIYDK--------DGYRRRAACICV- [26]
ce  ------------------------------------------MIS----------GWK---------------------------SRESERNKVRLRDT--------DGFRIRAAALCI- [32]
is  --------------------------------------------------------------------------------------MKEKPNSTRTYDE--------DGFRRRAACLCV- [25]
sc  ------------MGKTADNHGPV--------------------RS----------------------------------------ETAREGRENQVYSP-------VTGARLVAGCICL- [40]
sp  ---------------MLENNGSVILMEPDHLRTAV-------NRS----------------------------------------MTSREGRTKNRFNP-------ITGARLAAGVVAL- [50]
at  -------------------------------------MGVEKMVC----------------------------------------LASRTGRQFQRYN---------KGRRQVVGCVPY- [33]
at6 ------------------------------------------MVC----------------------------------------LVSRTGRQSQRYN---------KGRRQVVGCIPY- [28]
ec  ------------------------------------------MSK----------SLQKPTI-----------------------LNVETVARSRLFTVESVDLEFSNGVRRV-----Y- [39]
ec6 -----------------------------------------------------------------------------------------------MKD---------KVYKRPVSILVV- [15]
                                                                                                                  :         

hs  ----------RSE-RE--------------DEVLLVSSSRYPDRWI--------------VPGGGMEPEE-EPGGAAVREVYEEAGVKGKLGRL-LGVF-----------------EQNQ [87]
mm  ----------RSE-RE--------------DEVLLVSSSRYPDRWI--------------VPGGGMEPEE-EPDGAAVREVYEEAGVKGKLGRL-LGVF-----------------EQNQ [87]
mm6 ----------RSE-RE--------------DEVLLVSSSRYPDRWI--------------VPGGGMEPEE-EPDGAAVREVYEEAGVKGKLGRL-LGVF-----------------EQNQ [87]
rn  ----------RSE-RE--------------DEVLLVSSSRYPDRWI--------------VPGGGMEPEE-EPDGAAVREVYEEAGVKGKLGRL-LGVF-----------------EQNQ [87]
xt  ----------RNE-RE--------------DEVLLVSSSRYPDQWI--------------VPGGGMEPEE-EPGGAAVREVYEEAGVKGKLGRL-LGIF-----------------E-NQ [87]
dr  ----------KND-RE--------------DEVLLVSSSRHPDQWI--------------VPGGGMEPEE-EPGGAAVREVYEEAGVRGTLGRL-LGVF-----------------EQNQ [131]
dr6 ----------KND-RE--------------DEVLLVSSSRNPDQWI--------------VPGGGMEPEE-EPCGAAVREVYEEAGVKGKLGRL-LGVF-----------------EQNQ [87]
dm  ----------KSE-NE--------------AEVLLVTSSRRPELWI--------------VPGGGVEPEE-ESSVTAVREVLEEAGVVGDLGRC-LGVF-----------------E-NN [87]
ag  ----------RSE-AE--------------AEVLLVTSSRRPELWI--------------VPGGGVEPDE-EASLTATREVLEEAGVMGQLGRC-LGVF-----------------E-NS [87]
ce  ----------KGTGKE--------------TLVLLVSGGKDGGKWV--------------VPGGGIEKDE-CAEEAAHRELMEEAGVRATILKK-IGMF-----------------Q-DD [94]
is  ----------RRE--E--------------TEILLVSSSSAPDRWI--------------VPGGGLEPNE-EPSTAAMREVMEEGGVRGRLGRC-LGTF-----------------E-NL [85]
sc  ----------TPDK----------------KQVLMITSSAHKKRWI--------------VPKGGVEKDEPNYETTAQRETWEEAGCIGKIVAN-LGTVEDMRPPKDWN---KDIKQ-FE [115]
sp  ----------SADK----------------RKVLLVSSAKKHPSWV--------------VPKGGWEADE-SVQQAALREGWEEGGLVGHITRS-LGSFKDKRPTDTIDRRKKYLKQ-LM [127]
at  ----------RFKLSN-DGKISDE------VEVLVISSQKGH-ALM--------------FPKGGWELDE-SVEEAASRECLEEAGVLGNVEHQ-LGKW-----------------D-FL [101]
at6 ----------RLKISS-DGTISDE------FEVLVISSQKGH-ALM--------------FPKGGWELDE-SVEEAASRESLEEAGVVGNVERQ-LGKW-----------------D-FL [96]
ec  ----------ERMRPT------------NREAVMIVPIVDDHLILIREYAVGTESYEL-GFSKGLIDPGE-SVYEAANRELKEEVGFGANDLTF-LKKL-------------SMAPSYFS [121]
ec6 ----------IYAQDT--------------KRVLMLQRRDDPDFWQ--------------SVTGSVEEGE-TAPQAAMREVKEEVTI-DVVAEQ-LTLIDCQRTV-----------E-FE [82]
                                    ::                             *  :  *        :*  **           :                        

hs  DPKH-----------------------RTYVYVLTV-------------------TELLED----------W---------------EDSVSI----GRKREWFKVEDAIKVLQC-HKPV [135]
mm  DRKH-----------------------RTYVFVLTV-------------------TELLED----------W---------------EDSVSI----GRKREWFKIEDAIKVLQC-HKPV [135]
mm6 DRKH-----------------------RTYVFVLTV-------------------TELLED----------W---------------EDSVSI----GRKREWFKIEDAIKVLQC-HKPV [135]
rn  DRKH-----------------------RTYVFVLTV-------------------TELLED----------W---------------EDSVSI----GRKREWFKIEDAIKVLQC-HKPV [135]
xt  DRKH-----------------------RTYVYVLTV-------------------TEVLED----------W---------------EDSVNI----GRKREWFKVEDALKVLQC-HKPV [135]
dr  DSKH-----------------------RTYVYVLTV-------------------TETLED----------W---------------EDSVNI----GRKRKWFKIDEAIRVLQC-HKPF [179]
dr6 DRKH-----------------------RTYVYVLTV-------------------TETLDA----------W---------------EDSVNI----GRKREWFSVDEAIRVLQG-HKPV [135]
dm  DHMH-----------------------RTEVFVMNV-------------------TQELDE----------W---------------EDSRSI----GRKRQWFTIDDALSQLAL-HKPT [135]
ag  EHMH-----------------------RTEVFVMVV-------------------TQELDE----------W---------------EDSKTI----GRKRQWFSIEEAMSQLAL-HKPT [135]
ce  VRKH-----------------------RTQVFLMEV-------------------SEELQT----------W---------------EEN-EY----GRQRIWMNVLEGKEKV----KQS [138]
is  ERKH-----------------------RTMVFILEV-------------------TEELEE----------W---------------EDSKSI----GRKRKWFPIEEALRVLSV-SKPV [133]
sc  NSRKDSEVAKH------------PPRTEFHFYELEI-------------------ENLLDK----------F---------------PECHK------RHRKLYSYTEAKQNLI---DAK [170]
sp  SKSSGNDVSTNTELGAEAEKLLLPPRAECEFFEVIV-------------------ERLEDN----------Y---------------PEMRK------RRRKWMSYQEAKEAL-----TS [192]
at  SKSRGTYYE-------------------GLMFPMLV-------------------TEQLEL----------W---------------PEQHV------RQRIWMNVTEAREACR---DWW [149]
at6 SKSKGTFYE-------------------GFMFPMLV-------------------KEELEL----------W---------------PEQHL------RQRIWMKVDEARDACR---DWW [144]
ec  SKMN---------------IVV-----AQDLYPESL-EGDE--------------PEPLPQV--------RW-PLAHMMDLLEDPDFNEARNVSAL-FLVREWLKGQGRV---------- [186]
ec6 IFSH-----------------------LRHRYAPGV-------------------TRNTES----------WFCLA----------LPHERQIVFTEHLAYKWLDAPAAAALTK---SWS [137]
                                                                                                                            

hs  HAEYLEKLKL-G--------GSPTN----------------------------------GNSMAPS----------SPDSDP----------------------- [164]
mm  HAEYLEKLKL-G--------GSPTN----------------------------------GNSAAPS----------PPESEP----------------------- [164]
mm6 HAEYLEKLKL-G--------GSPTN----------------------------------GNSAAPS----------PPESEP----------------------- [164]
rn  HAEYLEKLKL-G--------GSPTN----------------------------------GNSAAPS----------PPESEP----------------------- [164]
xt  HAEYLEKLKL-G--------CSPTN----------------------------------GNSVVPP----------IPDNNSLYVTSAQTSSLPSTVR------- [180]
dr  HAEYLRKLTP-R--------CGPTN----------------------------------GNTQEPTM--------NTDDNASLRQTASHDCGLTRLHR------- [226]
dr6 HAEYLRRLRINR--------SSSTN----------------------------------GNLLLPQT--------NPSNLTPLFSTPA-----SATRR------- [178]
dm  QQHYLMQLQHSKTLDNTNRVVNATHPPKL------------------------------TNAATPA-------------ASP--TTA------------------ [177]
ag  QRHYLQQLRHSK-----HRTTSSSDPPPIISENDNDDFTSEPVMNNCTAPDDAAGEKDTTTESTPTTPPACTTTVTDDDGEP--TTVADTDSLPPTSTT------ [227]
ce  HRAMLDALTLLR--------------------------------------------------------------------------------------------- [150]
is  QCNYVKLLMK--------------------------------------------------NDKVP---------------------------------------- [148]
sc  RPELLEAL--------------------------------------------------------------NRSAIIKDDK------------------------- [188]
sp  RKDILAAL--------------------------------------------------------------EKSSIIKEEN------------------------- [210]
at  MKEALDVLVERLS-----------------------------------------------------------SPMNQPKEEKTMSISIET---------MC---- [182]
at6 MKEALDVLVQRLSL-------------------------------------------------------LSLKPMEEDENLPLISIY------------------ [176]
ec  --------------------------------------------------------------------------------------------------------- [186]
ec6 NRQAIEQFVINAA-------------------------------------------------------------------------------------------- [150]
                                                                                                             


Alignment Details

Alignment done with MAFFT FFT-NS-2 (v7.305b) aligner. MAFFT References
  • Strategy: Auto
  • Scoring Matrix: BLOSUM62
  • Gap Penalty: 1.53
  • Offset Value: 0.0