DRSC/TRiP Functional Genomics Resources

Multi Sequence Alignment :

Domains

Index TaxID Gene Name GeneID Protein ID Domain
start 		Domain
stop 		Domain
name 		Domain
description 		external_id
hs 9606 TMEM18 129787 NP_001339610.1 21 130 TMEM18 Transmembrane protein 18; pfam14770 CDD:405460
mm 10090 Tmem18 211986 NP_742046.2 130 138 Nuclear localization signal. /evidence=ECO:0000250 propagated from UniProtKB/Swiss-Prot (Q3TUD9.1)
mm 10090 Tmem18 211986 NP_742046.2 113 140 DNA-binding. /evidence=ECO:0000250 propagated from UniProtKB/Swiss-Prot (Q3TUD9.1)
mm 10090 Tmem18 211986 NP_742046.2 16 127 TMEM18 Transmembrane protein 18; pfam14770 CDD:405460
rn 10116 Tmem18 362722 NP_001007749.1 130 138 Nuclear localization signal. /evidence=ECO:0000250 propagated from UniProtKB/Swiss-Prot (Q6DGF8.1)
rn 10116 Tmem18 362722 NP_001007749.1 113 140 DNA-binding. /evidence=ECO:0000250 propagated from UniProtKB/Swiss-Prot (Q6DGF8.1)
rn 10116 Tmem18 362722 NP_001007749.1 16 127 TMEM18 Transmembrane protein 18; pfam14770 CDD:405460
xt 8364 tmem18 549089 NP_001016335.1 13 123 TMEM18 Transmembrane protein 18; pfam14770 CDD:405460
dr 7955 tmem18 449559 NP_001005601.1 124 152 DNA-binding. /evidence=ECO:0000250 propagated from UniProtKB/Swiss-Prot (Q641M3.1)
dr 7955 tmem18 449559 NP_001005601.1 27 144 TMEM18 Transmembrane protein 18; pfam14770 CDD:405460
dm 7227 Tmem18 246418 NP_725169.3 16 133 TMEM18 Transmembrane protein 18; pfam14770 CDD:405460
ag 7165 Tmem18 1274810 XP_061508625.1 - - - - -
is 6945 Tmem18 8025158 XP_002408197.2 20 137 TMEM18 Transmembrane protein 18; pfam14770 CDD:405460
at 3702 AT1G34350 840336 NP_001185136.1 39 181 TMEM18 Transmembrane protein 18; pfam14770 CDD:405460

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Alignment

Alignment done with MAFFT FFT-NS-2 (v7.305b) aligner. MAFFT References

Download raw alignment output file

Download fasta input file



Note:   &mbsp 2019, we've been having trouble with some alignments and are looking into the problem. If the alignment didn't work, please try again. If it still doesn't work, please download the fasta file and align off line. We're looking into it. Thanks.

hs  ---------------------MGTRWGLGRKP------CS--PHLRASGLLQ---TDWTEPWLMGLATFHALCVLLTCLSSRSYRLQIGHFLC-------------------------LV [63]
mm  ---------------------MSSAYSVRSFP------VS-IPAV----IME---TDWTEPWLLGLLAFHLLCLLLTCFSSQRYKLQIGHFLC-------------------------LV [60]
rn  ---------------------MASPYSVRVFP------VS-IPAV----IME---TDWTEPWLLGLLAFHLLCLLLTCFSAQRYKLQIGHFLC-------------------------LV [60]
xt  ---------------------------MAEDP-----------GLWT--LLERAPIDWKEPWLIGLAVFHILCLIVTYVSFKSYPLQICHFLL-------------------------MV [55]
dr  -------------------MTASNTKNASAIPIDKFSNVR-ITSIWT--FLQ--SVDWSEPWLMALLAFHVFCFAFTLLSCKYYRIQICHFLL-------------------------MV [71]
dm  -----------------------------MHP--GQIEVNEINGYWT--FLL--SIDWKDPWLIGLILAHILTTTTALLSRNSSNFQVFLFLV-------------------------LL [60]
ag  ----------------------------MVDP--TWIEVNEIKGFIT--FLS--SIDWYDPWLIGLIAFHICITSTALLTRNYGNFQVFLFFV-------------------------LL [61]
is  ---------------------MAEKVTDAMAP--PADPLN----IGN--ILV--HVDWTEPWLMGLITFHVAILSLTLLTRDRGNVQAGLFVT-------------------------AL [64]
at  MEEIRSAMEKQVDLVADLVEKLSGELRTGFQP--AYDNFL--------GFFH--AIDWKEPWIMGLMAFHALLLLVTLLSRRHLNFHMFLFLLACKFPLKLSIYILYKKSLRSNDLTSLV [108]
                                   *                 ::     ** :**::.*   *      : .:     .:   *.                           :

hs  ILVYCAEYINEAAAMNWRLFSKYQYFDSRGMFISIVFSAPLLVNAMIIVVMWVWKTLNVMTDLKNAQERRKEKKRRR-----------------KED- [143]
mm  VLVYSAEYINEVAAVNWRLFSKYQYFDSRGMFISLVFSAPLLFNAMLIVIMWVRKTLTVMTDLKTLQEERKERRRRR-----------------KEE- [140]
rn  VLVYCAEYINEVAAMNWRLFAKYQYFDSRGMFISLVFSAPLLFNAMVIVIMWVRKTLTVMSDLKNLQERRKERKRRR-----------------KEE- [140]
xt  VLVSCAEYINEFAAMHWRSYSKQQYFDSSGMFISLAFSAPLLCNTIIIVVHWVYKTLCVMTELKTLQQKRKESREKR-----------------KKKE [136]
dr  AMVYSAEYLNELAAMNWRSFSKFQYFDSKGMFISLVYSVPLLLNTVIIVAVWVWRTFSTMTELKILQLKRKAARENH-----------------KKTQ [152]
dm  LAVYFTESINEFAANNWSSFSRQQYFDSNGLFISTVFSIPILLNCMLLIGTWLYNSTQLMVTLKTAQLKERARK------ERQTKADSESIAHKKAE- [151]
ag  LLVYFSESINEYAAINWRIFSKQQYFDDKGLFISVVFSVPILLNCMLMVGSWLYQSTQLMSKLKTAQLKQQIRQS----NSRQRLKDA------KEE- [148]
is  LLVYFSEALNELAAQHWRSFSSHQYFDSQGMFISLVFSAPLLLNCIIMVGQWMWTSGTLMIRLKQAQLRQEIRRQRSANSNSHRSTDSSS----KED- [157]
at  AGVYFAENLNRELRKNWKSFSTQNYFDSNGVFLSTLWSGPLLVIAMIILINTLFSLCYLIVKWKRAELRHRARLAHT-----------------KEE- [188]
      *  :* :*.    :*  ::  :***. *:*:*  :* *:*   ::::   :      :   *  : ...                       *   


Alignment Details

Alignment done with MAFFT FFT-NS-2 (v7.305b) aligner. MAFFT References
  • Strategy: Auto
  • Scoring Matrix: BLOSUM62
  • Gap Penalty: 1.53
  • Offset Value: 0.0