DRSC/TRiP Functional Genomics Resources

Multi Sequence Alignment :

Domains

Index TaxID Gene Name GeneID Protein ID Domain
start 		Domain
stop 		Domain
name 		Domain
description 		external_id
hs 9606 IGF2BP2 10644 NP_001278798.1 432 508 KH-I_IGF2BP2_rpt3 third type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and similar proteins; cd22497 CDD:411925
hs 9606 IGF2BP2 10644 NP_001278798.1 82 163 RRM2_IGF2BP2 RNA recognition motif 2 (RRM2) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2); cd12629 CDD:410038
hs 9606 IGF2BP2 10644 NP_001278798.1 515 592 KH-I_IGF2BP2_rpt4 fourth type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and similar proteins; cd22500 CDD:411928
hs 9606 IGF2BP2 10644 NP_001278798.1 282 358 KH-I_IGF2BP2_rpt2 second type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and similar proteins; cd22494 CDD:411922
hs 9606 IGF2BP2 10644 NP_001278798.1 201 274 KH-I_IGF2BP2_rpt1 first type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and similar proteins; cd22491 CDD:411919
hs 9606 IGF2BP2 10644 NP_001278798.1 163 194 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite propagated from UniProtKB/Swiss-Prot (Q9Y6M1.2)
hs 9606 IGF2BP2 10644 NP_001278798.1 2 78 RRM1_IGF2BP2 RNA recognition motif 1 (RRM1) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2); cd12626 CDD:241070
mm 10090 Igf2bp2 319765 NP_898850.2 419 495 KH-I_IGF2BP2_rpt3 third type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and similar proteins; cd22497 CDD:411925
mm 10090 Igf2bp2 319765 NP_898850.2 265 360 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
mm 10090 Igf2bp2 319765 NP_898850.2 157 182 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite propagated from UniProtKB/Swiss-Prot (Q5SF07.1)
mm 10090 Igf2bp2 319765 NP_898850.2 82 157 RRM2_IGF2BP2 RNA recognition motif 2 (RRM2) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2); cd12629 CDD:410038
mm 10090 Igf2bp2 319765 NP_898850.2 2 78 RRM1_IGF2BP2 RNA recognition motif 1 (RRM1) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2); cd12626 CDD:241070
mm 10090 Igf2bp2 319765 NP_898850.2 502 579 KH-I_IGF2BP2_rpt4 fourth type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and similar proteins; cd22500 CDD:411928
mm 10090 Igf2bp2 319765 NP_898850.2 188 261 KH-I_IGF2BP2_rpt1 first type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and similar proteins; cd22491 CDD:411919
rn 10116 Igf2bp2 303824 NP_001257527.1 502 578 KH-I_IGF2BP2_rpt4 fourth type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and similar proteins; cd22500 CDD:411928
rn 10116 Igf2bp2 303824 NP_001257527.1 419 495 KH-I_IGF2BP2_rpt3 third type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and similar proteins; cd22497 CDD:411925
rn 10116 Igf2bp2 303824 NP_001257527.1 265 360 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
rn 10116 Igf2bp2 303824 NP_001257527.1 188 261 KH-I_IGF2BP2_rpt1 first type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and similar proteins; cd22491 CDD:411919
rn 10116 Igf2bp2 303824 NP_001257527.1 82 157 RRM2_IGF2BP2 RNA recognition motif 2 (RRM2) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2); cd12629 CDD:410038
rn 10116 Igf2bp2 303824 NP_001257527.1 2 78 RRM1_IGF2BP2 RNA recognition motif 1 (RRM1) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2); cd12626 CDD:241070
xt 8364 igf2bp3 549893 NP_001017139.1 1 77 RRM1_IGF2BP3 RNA recognition motif 1 (RRM1) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3); cd12627 CDD:410036
xt 8364 igf2bp3 549893 NP_001017139.1 81 156 RRM2_IGF2BP3 RNA recognition motif 2 (RRM2) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3); cd12630 CDD:410039
xt 8364 igf2bp3 549893 NP_001017139.1 415 492 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
xt 8364 igf2bp3 549893 NP_001017139.1 207 282 KH-I_IGF2BP1_rpt1 first type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22490 CDD:411918
xt 8364 igf2bp3 549893 NP_001017139.1 285 379 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
xt 8364 igf2bp3 549893 NP_001017139.1 500 571 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
dr 7955 igf2bp2a 100136839 NP_001108030.2 516 593 KH-I_IGF2BP2_rpt4 fourth type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and similar proteins; cd22500 CDD:411928
dr 7955 igf2bp2a 100136839 NP_001108030.2 433 509 KH-I_IGF2BP2_rpt3 third type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and similar proteins; cd22497 CDD:411925
dr 7955 igf2bp2a 100136839 NP_001108030.2 277 371 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
dr 7955 igf2bp2a 100136839 NP_001108030.2 199 272 KH-I_IGF2BP2_rpt1 first type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and similar proteins; cd22491 CDD:411919
dr 7955 igf2bp2a 100136839 NP_001108030.2 81 156 RRM_SF RNA recognition motif (RRM) superfamily; cl17169 CDD:473069
dr 7955 igf2bp2a 100136839 NP_001108030.2 1 77 RRM1_IGF2BP2 RNA recognition motif 1 (RRM1) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2); cd12626 CDD:241070
dm 7227 Imp 32009 NP_001245616.1 144 211 KH-I_IGF2BP_rpt1 first type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22400 CDD:411828
dm 7227 Imp 32009 NP_001245616.1 368 437 KH-I_IGF2BP_rpt3 third type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22402 CDD:411830
dm 7227 Imp 32009 NP_001245616.1 455 523 KH-I_IGF2BP_rpt4 fourth type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22403 CDD:411831
dm 7227 Imp 32009 NP_001245616.1 42 118 RRM2_VICKZ RNA recognition motif 2 (RRM2) found in the VICKZ family proteins; cd12359 CDD:409794
dm 7227 Imp 32009 NP_001245616.1 231 302 KH-I_IGF2BP_rpt2 second type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22401 CDD:411829
ag 7165 Imp 1280574 XP_061518433.1 - - - - -
ce 6239 imph-1 175595 NP_001263700.1 313 384 KH K homology RNA-binding domain; smart00322 CDD:197652
ce 6239 imph-1 175595 NP_001263700.1 569 >612 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
ce 6239 imph-1 175595 NP_001263700.1 709 783 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
ce 6239 imph-1 175595 NP_001263700.1 400 483 KH-I_IGF2BP_rpt2 second type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22401 CDD:411829
is 6945 Imp 115308414 XP_040078486.1 4 72 RRM1_VICKZ RNA recognition motif 1 (RRM1) found in the VICKZ family proteins; cd12358 CDD:240804
is 6945 Imp 115308414 XP_040078486.1 85 162 RRM2_VICKZ RNA recognition motif 2 (RRM2) found in the VICKZ family proteins; cd12359 CDD:409794
is 6945 Imp 115308414 XP_040078486.1 200 267 KH-I_IGF2BP_rpt1 first type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22400 CDD:411828
is 6945 Imp 115308414 XP_040078486.1 280 351 KH-I_IGF2BP_rpt2 second type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22401 CDD:411829
is 6945 Imp 115308414 XP_040078486.1 444 512 KH-I_IGF2BP_rpt3 third type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22402 CDD:411830
is 6945 Imp 115308414 XP_040078486.1 529 594 KH-I_IGF2BP_rpt4 fourth type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22403 CDD:411831
sc 4932 PBP2 852533 NP_009792.3 334 394 KH-I K homology (KH) RNA-binding domain, type I; cd00105 CDD:411802
sc 4932 PBP2 852533 NP_009792.3 150 218 KH-I_Rnc1_rpt2 second type I K homology (KH) RNA-binding domain found in Schizosaccharomyces pombe RNA-binding protein Rnc1 and similar proteins; cd22456 CDD:411884
sc 4932 HEK2 852248 NP_009521.1 257 330 KH K homology RNA-binding domain; smart00322 CDD:197652
sc 4932 PBP2 852533 NP_009792.3 69 137 KH-I_PCBP_rpt1 first type I K homology (KH) RNA-binding domain found in the family of poly(C)-binding proteins (PCBPs); cd22438 CDD:411866
sc 4932 HEK2 852248 NP_009521.1 44 113 KH-I_Rnc1_rpt1 first type I K homology (KH) RNA-binding domain found in Schizosaccharomyces pombe RNA-binding protein Rnc1 and similar proteins; cd22455 CDD:411883
sc 4932 HEK2 852248 NP_009521.1 158 226 KH-I_Rnc1_rpt2 second type I K homology (KH) RNA-binding domain found in Schizosaccharomyces pombe RNA-binding protein Rnc1 and similar proteins; cd22456 CDD:411884
at 3702 AT5G46190 834661 NP_001330854.1 44 125 KH-I_PEPPER_rpt1_like first type I K homology (KH) RNA-binding domain found in Arabidopsis thaliana RNA-binding KH domain-containing protein PEPPER and similar proteins; cd22459 CDD:411887
at 3702 AT5G46190 834661 NP_001330854.1 403 472 KH-I_PEPPER_rpt2_like second type I K homology (KH) RNA-binding domain found in Arabidopsis thaliana RNA-binding KH domain-containing protein PEPPER and similar proteins; cd22460 CDD:411888
at 3702 AT5G46190 834661 NP_001330854.1 577 686 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
at 3702 AT5G46190 834661 NP_001330854.1 151 223 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
at 3702 AT5G46190 834661 NP_001330854.1 316 385 KH-I_PEPPER_rpt1_like first type I K homology (KH) RNA-binding domain found in Arabidopsis thaliana RNA-binding KH domain-containing protein PEPPER and similar proteins; cd22459 CDD:411887
at 3702 AT4G18375 827566 NP_193572.1 36 114 KH-I_PEPPER_rpt1_like first type I K homology (KH) RNA-binding domain found in Arabidopsis thaliana RNA-binding KH domain-containing protein PEPPER and similar proteins; cd22459 CDD:411887
at 3702 AT4G18375 827566 NP_193572.1 538 603 KH-I_HEN4_like_rpt5 fifth type I K homology (KH) RNA-binding domain found in Arabidopsis thaliana KH domain-containing protein HEN4 and similar protein; cd22462 CDD:411890
at 3702 AT4G18375 827566 NP_193572.1 399 460 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
at 3702 AT4G18375 827566 NP_193572.1 311 381 KH-I_PEPPER_rpt1_like first type I K homology (KH) RNA-binding domain found in Arabidopsis thaliana RNA-binding KH domain-containing protein PEPPER and similar proteins; cd22459 CDD:411887
at 3702 AT4G18375 827566 NP_193572.1 140 212 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614

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Alignment

Alignment done with MAFFT FFT-NS-2 (v7.305b) aligner. MAFFT References

Download raw alignment output file

Download fasta input file



Note:   &mbsp 2019, we've been having trouble with some alignments and are looking into the problem. If the alignment didn't work, please try again. If it still doesn't work, please download the fasta file and align off line. We're looking into it. Thanks.

hs  MMNKL------YIGNLSPAVTADDLRQL----------------FGDRKLP-----------------------LAGQVLLKSGYAFVDYPDQNWAIRA----IETLSGKVE-LHG---- [66]
mm  MMNKL------YIGNLSPAVTADDLRQL----------------FGDRKLP-----------------------LAGQVLLKSGYAFVDYPDQNWAIRA----IETLSGKVE-LHG---- [66]
rn  MMNKL------YIGNLSPAVTADDLRQL----------------FGDRKLP-----------------------LAGQVLLKSGYAFVDYPDQNWAIRA----IETLSGKVE-LHG---- [66]
xt  -MNKL------YIGNLSENVSPPDLESL----------------FKESKIP-----------------------FTGQFLVKSGYAFVDCPDENWAMKA----IDTLSGKVE-LHG---- [65]
dr  -MNKL------YVGNLSPSVTVEDLKQL----------------FGERKLP-----------------------VTDQVLLKSGYAFVDFPDQNWAIKA----IETLSGKVE-LHG---- [65]
dm  ---------------MASELDQFADLELS---KEDREQI-----FDPP--------------------------LDRQQLEGAGTS---------------------------------- [37]
ag  ---------------MAQH--QYQQQQQQ---QTQQYQYQPISQFHSPGVDYGHSLVATGATAY--WYPGAGQYPDTHQAQNASSSFASGSGRTRTSRP----Y-SRDGQNEQFAS---- [89]
ce  -MEYFNAGGGGSTGNGSTDPYAVIPQQFGNGGQQPQQQV-----FTDYQQD-------GSATDYETYQQQQQQYRAAQASQQSSSMYYQ--NQMTAAQANYFPIHSASEHD--FLGPQQP [103]
is  -MNKL------YIGNLPADVNEGSIREL----------------FHEQ----------TGAS------------PKSVLVKKGGYAFVECADELAVGKA----IEALNGHS--FMG---- [65]
sc  ---------------MSTETTKPSITTTP------------------------------------------------------------------------------------------- [14]
sc6 -MSQ----------------------------------------FFEAATP--------------------------------------------------------------------- [10]
at  ------------------------------------------------------------------------------------------------------------------------ [0]
at6 ------------------------------------------------------------------------------------------------------------------------ [0]
                                                                                                                            

hs  --KIMEVD--YSVSK--KLRSRK---------------IQIRNIPPHLQWEVLDGLLAQYGTVENVEQVFAF-SLVNTDTETAVVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDE [164]
mm  --KIMEVD--YSVSK--KLRSRR---------------IQIRNIPPHLQWEVLDGLLAEYGTVENVEQ-------VNTDTETAVVNVTYMTREEAKLAIEKLSGHQFEDYSFKISYIPDE [158]
rn  --KIMEVD--YSVSK--KLRSRK---------------IQIRNIPPHLQWEVLDGLLAEYGTVENVEQ-------VNTDTETAVVNVTYMTREEAKVAIEKLSGHQFEDYSFKISYIPDE [158]
xt  --KVIEVE--HSVPK--RQRSRK---------------LQIRNIPPHLQWEVLDSLLAQYGTVENCEQ-------VNTDSETAVVNVTYANKEHARQGLEKLNGYQLENYSLKVTYIPDE [157]
dr  --KVIEVD--YSVPK--KLRSRK---------------IQIRNIPPHLQWEVLDSLLAQYGTVENVEQ-------VNTDTETAVVNVTYSTKEEAKVAVEKLIEQTFEDYSFKVSYIMDM [157]
dm  -----------------SVTTSK---------------ILISGIPMQTRFEDIEPLLKPYGIVKQCEAIS-----SK-DQNTQTVHITFENPEQAQRAAVGLNGVEFEGSKLHAEQ-LDK [118]
ag  --RNAFV----TSPNRVSSTTAK---------------IVISGIPQHAKFDDIEPLLKPYGKVEHCEAGT-----SK-DPNTQTVHITFENHDQAQRAVAGLNGVDFDGSKLLVEL-SDS [181]
ce  PSATTSVSGAAGAPYQSASGGNKEFMMQHQQRRGNQSGQQQQNQPSQQNNQQQQNQGARQQHPQQMQQQQQ----SNQSAHFMHQQLQAVQQQQAQQMHHRLQGAPINPQQFMVPPPTMM [219]
is  --SQLLVEPQQSAPQGRSSRGNR---------------VQVGNIPSHVKREDIHELLSTFGTIQNLDQVP-----SKPDSVTYRVQVTYESPDQAQQAVAQLRDYEYEGSALKADYPMDP [163]
sc  --TTVLVSP-NTLKRKKGEDTSE----------------------------------------EQLEAEIKRVALKDADSHS-------------------------------------- [53]
sc6 ----------VAIPTNNTNGGSS-------------------------------------------------------DA---------------------------------------- [25]
at  ----------------MVERKKR----------------------------------------KQIQR-------NNSESN--------------------------------------- [18]
at6 ----------------MVERGKR--------------------------------------THNRFRD-------NNNDNN--------------------------------------- [20]
                                                                                  .                                         

hs  EVSSPSPPQRAQR--------------------GDHSS----REQGHAPGGT------SQAR-QI-----------------------------------D---FPLRILVPTQFVGAII [215]
mm  EVSSPSPPHRA-------------------------------REQGHGPGSS------SQAR-QI-----------------------------------D---FPLRILVPTQFVGAII [202]
rn  ELSSPSPPHRA-------------------------------REQGHGPGSS------SQAR-QI-----------------------------------D---FPLRILVPTQFVGAII [202]
xt  MATQQAPSQQLQQQPQ-------QQHPQGRRGFGQRGP----ARQGS-PGAA------ARPKPQS-----------------------------------E---VPLRMLVPTQFVGAII [221]
dr  DAAAALPGTRNRR--------------------GGRTS----REQDSQPGTSGSS-LGSRQK-QP-----------------------------------D---FPLRMLVPTQFVGAII [213]
dm  NQ---RRSQRNQR-----------------------------NPYPGMP---------GPGR-QA-----------------------------------D---FPLRILVQSEMVGAII [158]
ag  NKQ-ARRAQRNRS-----------------------------QYGAGMPGGG------GPGR-QT-----------------------------------D---FPLRVLVQSEMVGAII [226]
ce  QPQQMQQAQQQQAQQMHQMQIHHQQHPQMM---------QQHAQQGYHPHQQNQQHQAGQHQ-QSHHQSQNHNQHRNHNQSHSGPHHIPQNLMMPRCMLKD---WPIRCVVEGKYHAVII [326]
is  NN---RNGSRNNTRV------------------GGRPPFRPFSYSGNQP---------SPLR-PS-----------------------------------D---FPLRILVLSDMVGAII [214]
sc  ------------------------------------------DNDHDSPDNV-----------PS-----------------------------------D---VHLRMLCLVKHASLIV [82]
sc6 ---------------------------------GS-------AATGGAP-------VVGTTA-QP-----------------------------------T---INHRLLLSLKEAAKII [59]
at  ---------RNQKRRI--------------------------SHD----------------KI-N----------------------------------RDEL-VVYRILCPIDVVGGVI [51]
at6 ---------RNQRRRL--------------------------SYES------------EEKKIDN----------------------------------KDDLVVVYRILCPSGVMGSVI [59]
                                                                                                               * :      . ::

hs  GKEGLTIKNITKQTQSRVD---IHRKENS--GAAEKPVTIHATPEG--------------------TSEACRMILEIMQKEA----DETKLAE--------------------EI----- [281]
mm  GKEGLTIKNITKQTQSRVD---IHRKENS--GAAEKPVTIHATPEG--------------------TSEACRMILEIMQKEA----DETKLAE--------------------EV----- [268]
rn  GKEGLTIKNITKQTQSRVD---IHRKENS--GAAEKPVTIHATPEG--------------------TSEACRMILEIMQKEA----DETKLAE--------------------EV----- [268]
xt  GKEGATIRNITKQTQSKID---IHRKENA--GAAEKPITIHSTPEG--------------------CSAACKIIMEIMQKEA----QDTKFTE--------------------EI----- [287]
dr  GKEGLTIKNITKQTQSKVD---IHRKENA--GAAEKPITIHSTPEG--------------------CSTACHMIMDIMQKEA----VDTKVTE--------------------DI----- [279]
dm  GRQGSTIRTITQQSRARVD---VHRKENV--GSLEKSITIYGNPEN--------------------CTNACKRILEVMQQEA----ISTNKGEL--------------SPECSEI----- [230]
ag  GRQGSTIRHITQQSRARVD---VHRKDNV--GSVEKAITIYGNPEN--------------------CTMACKKILEVMQQEA----NSTNKG---------------------EI----- [291]
ce  GPNGSTIKDIASSTRCRVDFVNLSKKERTVLGNNDRILTVHGVAEQ--------------------ATKAVARILDVIQSEAV--KDDVNVGA--------------------DT----- [399]
is  GRAGGTIRQITQQSRARVD---VHRKENA--GSLEKVITIYGNPEN--------------------CSTACQKILEVMQQEA----SNTNRG---------------------EV----- [279]
sc  GHKGATISRIKSETSARIN---ISNNIR---GVPERIVYVRGTCDD--------------------VAKAYGMIVRALLEEH----GNEDNGE-----------DI-------EI----- [149]
sc6 GTKGSTISRIRAANAVKIG---ISEKVP---GCSDRILSCAGNVIN--------------------VANAIGDIVDVLNKRNPE-NEDAAEGEAEEHYYFHFLNHILPAPSKDEIRDLQQ [152]
at  GKSGKVINAIRHNTKAKIK---VFDQLH---GCSQRVITIYCSVKEKQEEIGFTKSENE---PLCCAQDALLKVYDAIVASDEENNTKTNVDR-------------------DDNK---- [139]
at6 GKSGKVINLIRQETRARIK---VVDPFP---GCSERVITIFCSVSEKKDIVDIEYSELDYSVPLCSAQAALLKVHDAIVASLATAAENTKIDR-------------------DDFR---- [150]
    *  * .*  *   .  ::    :        *  :: :                               *   :   :         .                         :      

hs  -----PLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISS-------LQDLSIYNP----ERTITVKG-TVEACASAEIEIMKKL-----REAFEND------MLAVNQQANLIPGLN [373]
mm  -----PLKILAHNGFVGRLIGKEGRNLKKIEHETGTKITISS-------LQDLSIYNP----ERTITVRG-TIEACANAEIEIMKKL-----REAFEND------MLAVNQQANLIPGLN [360]
rn  -----PLKILAHNGFVGRLIGKEGRNLKKIEHETGTKITISS-------LQDLSIYNP----ERTITVKG-TIEACASAEMEIMKKL-----REAFEND------MLAVNQQANLIPGLN [360]
xt  -----PLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISP-------LQDLTLYNP----ERTITVKG-SIEACAKAEEEIMKKI-----RESYEND------IAAMNLQAHLIPGLN [379]
dr  -----PLKILAHNSLVGRLIGKEGRNLKKIEEDTETKITISS-------LQDLTIYNP----ERTIIVKG-SIEACCRAEVEIMKKL-----REAYEND------VAAINQQSNLIPGLS [371]
dm  -----CLKILAHNNLIGRIIGKSGNTIKRIMQDTDTKITVSS-------INDINSFNL----ERIITVKG-LIENMSRAENQISTKL-----RQSYEND------LQAMAPQSLMFPGLH [322]
ag  -----CLKILAHNNLIGRIIGKSGNTIKRIMQDTDTKITVSS-------INDISSFNL----ERIITVKG-SIENMSKGESQISAKL-----RQSYEND------LQALAPQTIMFPGLH [383]
ce  -----VLRMRAHNQLCGRLIGKAGSSIKEIMQKTGTNITVTKYIEPPGGISGLTANELLGLMERTIMVRGPSIEAVVQAEALISAKL-----KKCYESDS----QLRAQSMQCPMPPMMM [505]
is  -----PLKILAHNNLIGRIIGKSGNTIKRIMEQTDTKITVSS-------LHDASTLNL----ERVITVKG-KAEGVCRAEQLISAKL-----RQSYESD------LAALAPQTLMFPGLH [371]
sc  -----SINLLIPHHLMGCIIGKRGSRLREIEDLSAAKLFASPNQLL---LSN----------DRILTING-VPDAIHIATFYISQTLLNF-QMESPQKNVKRSIYYQPTQFNSVLIDHSQ [249]
sc6 LEDIGYVRLIVANSHISSIIGKAGATIKSLINKHGVKIVASKDFLP---ASD----------ERIIEIQG-----FPGSITNVLIEI-----SEIILSDV-----DVRFSTERSYFPHLK [244]
at  -----ECRLLVPFSQSSSLIGKAGENIKRIRRRTRASVKVVS-----KDVSDPSHVCAMEY-DNVVVISG-EPESVKQALFAVSAIMYKINPRENIPLDST----SQDVPAASVIVPSDL [243]
at6 -----ECRLLVPSSQCSIVIGKSGSIIKNIRGRTRANVKVVS-----KDVSDPSHTCAMDF-DNIVMISG-ETESVKKALFAVSAIMYKVSPREQIPLDTT----VQEVP-ASIIIPSDL [253]
           .:       . :*** *  :: :     ..:             .          :. : : *        .   :   :      :    :                     

hs  LSALGIFSTGLSVLSPPAGP-------------------RGAP-PAAP--------YHPFTTHSGYFSSLYPHHQFG-PFPHH-----------HSY-P-----------EQEIVNLFIP [441]
mm  LSALGIFSTGLSVLPPPAGP-------------------RGVP-PSPP--------YHPFATHSGYFSSLYPHHHFG-PFPHH-----------HSY-P-----------EQETVSLFIP [428]
rn  LSALGIFSTGLSVLPPPAGP-------------------RGAP-PSPP--------YHPFATHSGYFSSLYPHHHFG-PFPHH-----------HSY-P-----------EQETVSLFIP [428]
xt  LNALGLFPPSSSGMPPPS---------------------VGVPSPTTST------SYPPFGQQ-----------------------------------P-----------ESETVHLFIP [426]
dr  LSALGIFSTGLSVLPPAAGP-------------------RGIP-PVPPT------GYNPFLGHSSQLGGLYGVPPAS-GISHQ-----------HTQAP-----------EQEVVYLFIP [442]
dm  PMAM------MST---PGNGMVFN---------------TSMPFPSCQSF----AMSKT------------PA---------------------SVVPPV------FPNDLQETTYLYIP [375]
ag  PMAM------MST---AGNGMGFTGRTAGATASASGSGATGM-YPG-SNF----PMYQP------------PA-----GGP-------------AGVPP-------GSSEVQETTYLYIP [451]
ce  PPIL-----------PPGAS------------SSAVSAPHFIPTPVGVMQ----VQHFASSQH----------------LVHQNANNSFLQPGVLQIQP--------GTTNLRQVRMWVP [574]
is  PMTM------MSTYPPPGPPM--------------------RPQPHQHHQ----PMHHPQQPHQNARGGYYPSHHQGYGGPHHGGGGHLVYPNQGGAGP----------DGRELVYLYIP [451]
sc  PNTI--FHQRNHQYHPSDKLL----------------------------------SYKPNKNL-----------------------------------PI----------SSTLLSMATP [288]
sc6 ----------KSSGEPTS--------------------------------------------------------------------------------P--------STSSNTRIELKIP [266]
at  SNSV--YP--QTGFYSNQDHILQQG--------------AGVPSYFNALSVSDFQGYAETAAN--------PVPVF------------------ASSLPVTHGFGGSSRSEELVFKVLCP [319]
at6 --SI--YP--QAGLYPSQDSIFQHG--------------ANVSSFIGTLP----QGYGENAAN--------PVPVFS-----------------ASALPVVHGFGGSSRSEKLAIKVICS [324]
                                                                                                      *                 :  .

hs  TQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVS---------------------------------------------------ERMVIITGPPEAQFKAQGRIFGKLKEENFFNP [510]
mm  TQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVS---------------------------------------------------ERMVIITGPPEAQFKAQGRIFGKLKEENFFNP [497]
rn  TQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVS---------------------------------------------------ERMVIITGPPEAQFKAQGRIFGKLKEENFFNP [497]
xt  ALAVGAIIGKQGQHIKQLSRFAGASIKIAPAEGPDAK---------------------------------------------------LRMVIITGPPEAQFKAQGRIYGKLKEENFFGP [495]
dr  TQAVGAIIGKKGQHIKQLARFAGASIKIAPAESPDVT---------------------------------------------------QRMVIITGPPEAQFKAQGRIFGKLKEENFFTA [511]
dm  NNAVGAIIGTRGSHIRSIMRFSNASLKIAPLDADKPLDQQ-----------------------------------------------TERKVTIVGTPEGQWKAQYMIFEKMREEGFMCG [448]
ag  NNAVGAIIGTKGLHIRNIIRFSGASVKIAPLEADKPQEQQ-----------------------------------------------TERKVTIIGTPEAQWKAQYLIFEKMREEGFVSG [524]
ce  DSMIGALIGAKGKNIKMIIRDTGASVKIEAPEEKTQREAEEAEKKRKLDETDSGCEGVASGDHPQEFLEDNATINSSDAIEEKPKPVSERMVTINGDDLQLLKAQSYVFSKIAETSSSLP [694]
is  NVAVGAVIGTGGSSIRDMIMLSGASIKVAQPNRDDPADAH------------------------------------------------ERKVTIVGTPESQWRAQGMIFNKVCYEG-CAG [522]
sc  -------------------QYTTASVANATAFQPN--------------------------------------------------FVIPNVTVLDGPVISPAPGNHLLMNFVQQE----- [334]
sc6 ELYVGAIIGRGMNRIKNLKTFTKTNIVVERKDDDDKDENF------------------------------------------------RKFIITSKFPKNVKLAESMLLKNLNTE----- [333]
at  LCNIMRVIGKGGSTIKRIREASGSCIEVNDSRTKC-------------------------GD--------------------------DECVIIVTATESPDDMKSMAVEAVLLLQEYIN [388]
at6 SSKIGRVIGKGGLTIKGIRQASGSHIEVNDSRTN--------------------------HD--------------------------DDCVITVTATESPDDLKSMAVEAVLLLQEKIN [392]
                         : : :                                                                              :      :        

hs  KEEV--------KLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDEN----------EEVIVRIIGHFFASQTAQRKIREIVQQVK------------QQEQK------ [594]
mm  KEEV--------KLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDEN----------EEVIVRIIGHFFASQTAQRKIREIVQQVK------------QQEQR------ [581]
rn  KEEV--------KLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDEN----------EEVIVRIIGHFFASQTAQRKIREIVQQVK------------QQAQK------ [581]
xt  KEEV--------KLEAHIKVPSYAAGRVIGKGGKTVNELQNLTSAEVVVPRDQTPDEN----------DQVVVKITGHFYASQLAQRKIQEILAQVRR---------QQQQQQK------ [582]
dr  KEEV--------KLETHIKVPSSAAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDEN----------DEVFVKISGHFFASQTAQRKIREIIQQVK------------QQEQK------ [595]
dm  TDDV--------RLTVELLVASSQVGRIIGKGGQNVRELQRVTGSVIKLPEHALAPPSG-------GDEETPVHIIGLFYSVQSAQRRIRAM-----MLSTNPPPITKKQKAAKEQLQQQ [548]
ag  TDDV--------RLTVEIFVPSAQVGRIIGKGGQNVRELQRVTGSIIKLPEHTASAPV---------DEETTVHIIGPFFSVQSAQRRIRTM-----MLATNPPPVTKRQTSQK----AK [618]
ce  SSGMDGDRSHMLRIRTEVSVPTRIIGRIIGKGGQNVRELQRITGAVVKIPEEERNGGEVYRHDDGLEEDMTMIRTIGNMYSTHNVQFRLAHLVNEYYRSGDH----RNKSSDYK------ [804]
is  SQDG--------TLRVEIFVPSNQVGRIIGKGGQTVRELQRLTRALIKLPDESQNANS----------EETPVHILGEFFSSQAAQRQIRALVSRNQMAGQQPYPMHPRSNNNN----GP [620]
sc  -----------------IFIDEKFVGNVIGKDGKHINSVKESTGCSIIIQDPVEGSSE----------RRLTIR--GTFMASQAAIMLISNKIE------------IDRSNAER------ [407]
sc6 ----------------------------IEKRENYKRKLEAAEGDATVVTERSDSASF-------LEEKEEP-----------------------------------QENHDNK------ [377]
at  DEDAE-------NVKMQLLVSSKVIGCVIGKSGSVINEIRKRTNANICISKGK---------------KDDLVEVSGEVSSVRDALIQIVLRLREDVL--------GDKDSVATRKPPAR [478]
at6 DEDED-------KVKMQLLVSSKVIGCIIGKSGSIISEIRKRTKADIHISKGNNTPKC-------ADPNDELVEISGEVSNVRDALIQIVLRLRDDVL--------RDRETGSRNQPPAR [490]
                                * *  .   .:.        :                                                            .          

hs  ------------------------------------------------------------------------------------------------------------------------ [594]
mm  ------------------------------------------------------------------------------------------------------------------------ [581]
rn  ------------------------------------------------------------------------------------------------------------------------ [581]
xt  ------------------------------------------------------------------------------------------------------------------------ [582]
dr  ------------------------------------------------------------------------------------------------------------------------ [595]
dm  QQSL----AGAASSGSQQQQPQSPSQQQALP-------PQLH----------------HQPVSSASSSSTPPAHHQQQASTAATSHQL-------------------------------Q [610]
ag  DQTT----GGATT-----------------------------------------------PAAGATAATT---------TTAAVT----------------------------------- [643]
ce  --------GGRPHSA---------------------------------------------PSSGQEKDGSALEKMDQLGTIAPISNS--------------------------------- [838]
is  RRNV----SGEPR-----------------------------------------------------GNNGPPA----------------------------------------------- [636]
sc  ------------------------------------------------------------------------------------------------------------------------ [407]
sc6 ------------------------------------------------------------------------------------------------------------------------ [377]
at  TDNCSFL-SGSSNAG------------YTLP-SFMSS---------------------MASTSGFHGYGSFPAGDNVLGSTGPYS---YGRLPSSSALEILIPAHAMSKVMGKGGGNLEN [560]
at6 SENNNFFSSSSSNTG------------LALPQSFMSSVPQVASVDFNRRPETGSSMSMLPSSGGIYGYGSFPVGNTSYGSNSSYSSNLYGGLPQSTTMEVRIPANAVGKVMGRGGGNLDN [598]
                                                                                                                            

hs  -------------------------------------------------------------------------YPQGVASQ-RSK------ [605]
mm  -------------------------------------------------------------------------YPQGVAPQ-RSK------ [592]
rn  -------------------------------------------------------------------------YPQGVAPQ-RSK------ [592]
xt  -------------------------------------------------------------------------TAQSGQPQPRRK------ [594]
dr  -------------------------------------------------------------------------HQQGAPTTPRSK------ [607]
dm  QQQ------------------------------------------------------PSPPPPGNATAAAAQQQQQLASSQQ--------- [638]
ag  ----------------------------------------------------------TTPP-----------QQQSSSTNA--------- [656]
ce  -NR------------------------------------------------------ASPKSVS---------PPKSKSP----------- [854]
is  -RR------------------------------------------------------PSPPS--------AAHDSQGGSQDSN-------- [656]
sc  -KR------------------------------------------------------RSPL------------------------------ [413]
sc6 -------------------------------------------------------------------------EEQS-------------- [381]
at  IRR---------------------------------------------ISGAMIEISASKTSHGDHIALLSGTLEQMRCAENLVQAFVMST [606]
at6 IRRVCLIFIFIFPSSLLSDCHSFIRLFFPLSYITFSHGMCPLSLSLSQISGAMIEISDSKNSHGGRVALISGTSEQKRTAENLFQAFIMST [689]
                                                                                               


Alignment Details

Alignment done with MAFFT FFT-NS-2 (v7.305b) aligner. MAFFT References
  • Strategy: Auto
  • Scoring Matrix: BLOSUM62
  • Gap Penalty: 1.53
  • Offset Value: 0.0