DRSC/TRiP Functional Genomics Resources

Multi Sequence Alignment :

Domains

Index TaxID Gene Name GeneID Protein ID Domain
start 		Domain
stop 		Domain
name 		Domain
description 		external_id
hs 9606 IGF2BP1 10642 NP_006537.3 485 495 Sufficient for nuclear export propagated from UniProtKB/Swiss-Prot (Q9NZI8.2)
hs 9606 IGF2BP1 10642 NP_006537.3 487 562 KH-I_IGF2BP1_rpt4 fourth type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22499 CDD:411927
hs 9606 IGF2BP1 10642 NP_006537.3 310 324 Sufficient for nuclear export propagated from UniProtKB/Swiss-Prot (Q9NZI8.2)
hs 9606 IGF2BP1 10642 NP_006537.3 404 479 KH-I_IGF2BP1_rpt3 third type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22496 CDD:411924
hs 9606 IGF2BP1 10642 NP_006537.3 273 369 KH-I_IGF2BP1_rpt2 second type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22493 CDD:411921
hs 9606 IGF2BP1 10642 NP_006537.3 197 272 KH-I_IGF2BP1_rpt1 first type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22490 CDD:411918
hs 9606 IGF2BP1 10642 NP_006537.3 160 190 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite propagated from UniProtKB/Swiss-Prot (Q9NZI8.2)
hs 9606 IGF2BP1 10642 NP_006537.3 81 156 RRM2_IGF2BP1 RNA recognition motif 2 (RRM2) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1); cd12628 CDD:410037
hs 9606 IGF2BP1 10642 NP_006537.3 1 77 RRM1_IGF2BP1 RNA recognition motif 1 (RRM1) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1); cd12625 CDD:241069
mm 10090 Igf2bp1 140486 NP_034081.1 273 369 KH-I_IGF2BP1_rpt2 second type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22493 CDD:411921
mm 10090 Igf2bp1 140486 NP_034081.1 312 323 Sufficient for nuclear export. /evidence=ECO:0000250 propagated from UniProtKB/Swiss-Prot (O88477.1)
mm 10090 Igf2bp1 140486 NP_034081.1 404 479 KH-I_IGF2BP1_rpt3 third type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22496 CDD:411924
mm 10090 Igf2bp1 140486 NP_034081.1 197 272 KH-I_IGF2BP1_rpt1 first type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22490 CDD:411918
mm 10090 Igf2bp1 140486 NP_034081.1 487 562 KH-I_IGF2BP1_rpt4 fourth type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22499 CDD:411927
mm 10090 Igf2bp1 140486 NP_034081.1 485 495 Sufficient for nuclear export. /evidence=ECO:0000250 propagated from UniProtKB/Swiss-Prot (O88477.1)
mm 10090 Igf2bp1 140486 NP_034081.1 156 190 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite propagated from UniProtKB/Swiss-Prot (O88477.1)
mm 10090 Igf2bp1 140486 NP_034081.1 1 77 RRM1_IGF2BP1 RNA recognition motif 1 (RRM1) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1); cd12625 CDD:241069
mm 10090 Igf2bp1 140486 NP_034081.1 81 156 RRM2_IGF2BP1 RNA recognition motif 2 (RRM2) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1); cd12628 CDD:410037
rn 10116 Igf2bp1 303477 NP_783184.1 1 77 RRM1_IGF2BP1 RNA recognition motif 1 (RRM1) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1); cd12625 CDD:241069
rn 10116 Igf2bp1 303477 NP_783184.1 487 562 KH-I_IGF2BP1_rpt4 fourth type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22499 CDD:411927
rn 10116 Igf2bp1 303477 NP_783184.1 485 495 Sufficient for nuclear export. /evidence=ECO:0000250 propagated from UniProtKB/Swiss-Prot (Q8CGX0.1)
rn 10116 Igf2bp1 303477 NP_783184.1 404 479 KH-I_IGF2BP1_rpt3 third type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22496 CDD:411924
rn 10116 Igf2bp1 303477 NP_783184.1 312 323 Sufficient for nuclear export. /evidence=ECO:0000250 propagated from UniProtKB/Swiss-Prot (Q8CGX0.1)
rn 10116 Igf2bp1 303477 NP_783184.1 273 369 KH-I_IGF2BP1_rpt2 second type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22493 CDD:411921
rn 10116 Igf2bp1 303477 NP_783184.1 197 272 KH-I_IGF2BP1_rpt1 first type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22490 CDD:411918
rn 10116 Igf2bp1 303477 NP_783184.1 160 190 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite propagated from UniProtKB/Swiss-Prot (Q8CGX0.1)
rn 10116 Igf2bp1 303477 NP_783184.1 81 156 RRM2_IGF2BP1 RNA recognition motif 2 (RRM2) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1); cd12628 CDD:410037
xt 8364 igf2bp3 549893 NP_001017139.1 1 77 RRM1_IGF2BP3 RNA recognition motif 1 (RRM1) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3); cd12627 CDD:410036
xt 8364 igf2bp3 549893 NP_001017139.1 81 156 RRM2_IGF2BP3 RNA recognition motif 2 (RRM2) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3); cd12630 CDD:410039
xt 8364 igf2bp3 549893 NP_001017139.1 285 379 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
xt 8364 igf2bp3 549893 NP_001017139.1 207 282 KH-I_IGF2BP1_rpt1 first type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22490 CDD:411918
xt 8364 igf2bp3 549893 NP_001017139.1 500 571 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
xt 8364 igf2bp3 549893 NP_001017139.1 415 492 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
dr 7955 igf2bp1 558182 NP_001070027.2 1 77 RRM1_IGF2BP1 RNA recognition motif 1 (RRM1) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1); cd12625 CDD:241069
dr 7955 igf2bp1 558182 NP_001070027.2 81 156 RRM2_IGF2BP3 RNA recognition motif 2 (RRM2) found in vertebrate insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3); cd12630 CDD:410039
dr 7955 igf2bp1 558182 NP_001070027.2 561 598 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite propagated from UniProtKB/Swiss-Prot (Q08CK7.1)
dr 7955 igf2bp1 558182 NP_001070027.2 489 564 KH-I_IGF2BP1_rpt4 fourth type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22499 CDD:411927
dr 7955 igf2bp1 558182 NP_001070027.2 406 481 KH-I_IGF2BP1_rpt3 third type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22496 CDD:411924
dr 7955 igf2bp1 558182 NP_001070027.2 276 372 KH-I_IGF2BP1_rpt2 second type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22493 CDD:411921
dr 7955 igf2bp1 558182 NP_001070027.2 200 275 KH-I_IGF2BP1_rpt1 first type I K homology (KH) RNA-binding domain found in insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) and similar proteins; cd22490 CDD:411918
dr 7955 igf2bp1 558182 NP_001070027.2 155 195 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite propagated from UniProtKB/Swiss-Prot (Q08CK7.1)
dm 7227 Imp 32009 NP_001245616.1 455 523 KH-I_IGF2BP_rpt4 fourth type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22403 CDD:411831
dm 7227 Imp 32009 NP_001245616.1 368 437 KH-I_IGF2BP_rpt3 third type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22402 CDD:411830
dm 7227 Imp 32009 NP_001245616.1 231 302 KH-I_IGF2BP_rpt2 second type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22401 CDD:411829
dm 7227 Imp 32009 NP_001245616.1 42 118 RRM2_VICKZ RNA recognition motif 2 (RRM2) found in the VICKZ family proteins; cd12359 CDD:409794
dm 7227 Imp 32009 NP_001245616.1 144 211 KH-I_IGF2BP_rpt1 first type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22400 CDD:411828
ag 7165 Imp 1280574 XP_061518433.1 - - - - -
ce 6239 imph-1 175595 NP_001263700.1 313 384 KH K homology RNA-binding domain; smart00322 CDD:197652
ce 6239 imph-1 175595 NP_001263700.1 400 483 KH-I_IGF2BP_rpt2 second type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22401 CDD:411829
ce 6239 imph-1 175595 NP_001263700.1 569 >612 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
ce 6239 imph-1 175595 NP_001263700.1 709 783 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
is 6945 Imp 115308414 XP_040078486.1 4 72 RRM1_VICKZ RNA recognition motif 1 (RRM1) found in the VICKZ family proteins; cd12358 CDD:240804
is 6945 Imp 115308414 XP_040078486.1 529 594 KH-I_IGF2BP_rpt4 fourth type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22403 CDD:411831
is 6945 Imp 115308414 XP_040078486.1 444 512 KH-I_IGF2BP_rpt3 third type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22402 CDD:411830
is 6945 Imp 115308414 XP_040078486.1 280 351 KH-I_IGF2BP_rpt2 second type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22401 CDD:411829
is 6945 Imp 115308414 XP_040078486.1 200 267 KH-I_IGF2BP_rpt1 first type I K homology (KH) RNA-binding domain found in the insulin-like growth factor 2 mRNA-binding protein (IGF2BP) family; cd22400 CDD:411828
is 6945 Imp 115308414 XP_040078486.1 85 162 RRM2_VICKZ RNA recognition motif 2 (RRM2) found in the VICKZ family proteins; cd12359 CDD:409794
sc 4932 PBP2 852533 NP_009792.3 334 394 KH-I K homology (KH) RNA-binding domain, type I; cd00105 CDD:411802
sc 4932 PBP2 852533 NP_009792.3 150 218 KH-I_Rnc1_rpt2 second type I K homology (KH) RNA-binding domain found in Schizosaccharomyces pombe RNA-binding protein Rnc1 and similar proteins; cd22456 CDD:411884
sc 4932 HEK2 852248 NP_009521.1 257 330 KH K homology RNA-binding domain; smart00322 CDD:197652
sc 4932 PBP2 852533 NP_009792.3 69 137 KH-I_PCBP_rpt1 first type I K homology (KH) RNA-binding domain found in the family of poly(C)-binding proteins (PCBPs); cd22438 CDD:411866
sc 4932 HEK2 852248 NP_009521.1 44 113 KH-I_Rnc1_rpt1 first type I K homology (KH) RNA-binding domain found in Schizosaccharomyces pombe RNA-binding protein Rnc1 and similar proteins; cd22455 CDD:411883
sc 4932 HEK2 852248 NP_009521.1 158 226 KH-I_Rnc1_rpt2 second type I K homology (KH) RNA-binding domain found in Schizosaccharomyces pombe RNA-binding protein Rnc1 and similar proteins; cd22456 CDD:411884
at 3702 AT4G18375 827566 NP_193572.1 311 381 KH-I_PEPPER_rpt1_like first type I K homology (KH) RNA-binding domain found in Arabidopsis thaliana RNA-binding KH domain-containing protein PEPPER and similar proteins; cd22459 CDD:411887
at 3702 AT5G46190 834661 NP_001330854.1 403 472 KH-I_PEPPER_rpt2_like second type I K homology (KH) RNA-binding domain found in Arabidopsis thaliana RNA-binding KH domain-containing protein PEPPER and similar proteins; cd22460 CDD:411888
at 3702 AT5G46190 834661 NP_001330854.1 577 686 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
at 3702 AT5G46190 834661 NP_001330854.1 151 223 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
at 3702 AT5G46190 834661 NP_001330854.1 316 385 KH-I_PEPPER_rpt1_like first type I K homology (KH) RNA-binding domain found in Arabidopsis thaliana RNA-binding KH domain-containing protein PEPPER and similar proteins; cd22459 CDD:411887
at 3702 AT5G46190 834661 NP_001330854.1 44 125 KH-I_PEPPER_rpt1_like first type I K homology (KH) RNA-binding domain found in Arabidopsis thaliana RNA-binding KH domain-containing protein PEPPER and similar proteins; cd22459 CDD:411887
at 3702 AT4G18375 827566 NP_193572.1 538 603 KH-I_HEN4_like_rpt5 fifth type I K homology (KH) RNA-binding domain found in Arabidopsis thaliana KH domain-containing protein HEN4 and similar protein; cd22462 CDD:411890
at 3702 AT4G18375 827566 NP_193572.1 399 460 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614
at 3702 AT4G18375 827566 NP_193572.1 36 114 KH-I_PEPPER_rpt1_like first type I K homology (KH) RNA-binding domain found in Arabidopsis thaliana RNA-binding KH domain-containing protein PEPPER and similar proteins; cd22459 CDD:411887
at 3702 AT4G18375 827566 NP_193572.1 140 212 KH-I K homology (KH) RNA-binding domain, type I; cl00098 CDD:469614

Highlight Region

select the species and region you wish to highlight

Alignment

Alignment done with MAFFT FFT-NS-2 (v7.305b) aligner. MAFFT References

Download raw alignment output file

Download fasta input file



Note:   &mbsp 2019, we've been having trouble with some alignments and are looking into the problem. If the alignment didn't work, please try again. If it still doesn't work, please download the fasta file and align off line. We're looking into it. Thanks.

hs  MNKLYIG--------------NLNESVTPADLEKV------------------FAEHKISY------SGQF---------------LVKSGYAFVDCPDEH-----------------WA [50]
mm  MNKLYIG--------------NLNESVTPADLEKV------------------FAEHKISY------SGQF---------------LVKSGYAFVDCPDEH-----------------WA [50]
rn  MNKLYIG--------------NLNESVTPADLEKV------------------FAEHKISY------SGQF---------------LVKSGYAFVDCPDEH-----------------WA [50]
xt  MNKLYIG--------------NLSENVSPPDLESL------------------FKESKIPF------TGQF---------------LVKSGYAFVDCPDEN-----------------WA [50]
dr  MNKLYIG--------------NLNEKVTAEDLVKT------------------FEDYKIPY------SGQF---------------LMKTGYAFVDCPDDQ-----------------WA [50]
dm  ----------------------MASELDQFADLELSK--EDREQI--------FDPP------------------------LDRQQLEGAGTS--------------------------- [37]
ag  ----------------------MAQH--QYQQQQQQQ--TQQYQYQPIS---QFHSPGVDYGHSLVATGATAYWYPGAGQYPDTHQAQNASSSFASGSGRT-----------------RT [74]
ce  MEYFNAGGGGSTGNGSTDPYAVIPQQFGNGGQQPQQQVFTDYQQDGSATDYETYQQQQQQY-RAAQASQQSSSMY-----YQNQMTAAQANYFPIHSASEHDFLGPQQPPSATTSVSGAA [114]
is  MNKLYIG--------------NLPADVNEGSIREL------------------FHEQ----------TGAS----------PKSVLVKKGGYAFVECADEL-----------------AV [51]
sc  ------------------------------------------------------------------------------------------------------------------------ [0]
sc6 MSQF-------------------------------------------------FEAA------------------------------------------------------------TPV [11]
at  ------------------------------------------------------------------------------------------------------------------------ [0]
at6 ------------------------------------------------------------------------------------------------------------------------ [0]
                                                                                                                            

hs  MKAIETFSGKVE-LQ-----------GKRLEIE-----------HSVPK--KQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNT--------ESETAVVNVTYSNREQTRQA-- [135]
mm  MKAIETFSGKVE-LQ-----------GKRLEIE-----------HSVPK--KQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNT--------ESETAVVNVTYSNREQTRQA-- [135]
rn  MKAIETFSGKVE-LQ-----------GKRLEIE-----------HSVPK--KQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNT--------ESETAVVNVTYSNREQTRQA-- [135]
xt  MKAIDTLSGKVE-LH-----------GKVIEVE-----------HSVPK--RQRSRKLQIRNIPPHLQWEVLDSLLAQYGTVENCEQVNT--------DSETAVVNVTYANKEHARQG-- [135]
dr  MKAIETFSGKVE-LH-----------GKRIEVE-----------HSVPK--KQRTRKLQIRNIPPHLQWEVLDGLLAQYGTVENCEQVNT--------DSETAVVNVTYGTREQARQA-- [135]
dm  ---------------------------------------------------SVTTSKILISGIPMQTRFEDIEPLLKPYGIVKQCEAISSK-------DQNTQTVHITFENPEQAQRA-- [97]
ag  SRPY-SRDGQNEQFA-----------SRNAFV-------------TSPNRVSSTTAKIVISGIPQHAKFDDIEPLLKPYGKVEHCEAGTSK-------DPNTQTVHITFENHDQAQRA-- [160]
ce  GAPYQSASGGNKEFMMQHQQRRGNQSGQQQQNQPSQQNNQQQQNQGARQQHPQQMQQQQQSNQSAHFMHQQLQAVQQ-----QQAQQMHHRLQGAPINPQQFMVPPPTMMQPQQMQQAQQ [229]
is  GKAIEALNGHS--FM-----------GSQLLVEP---------QQSAPQGRSSRGNRVQVGNIPSHVKREDIHELLSTFGTIQNLDQVPSK------PDSVTYRVQVTYESPDQAQQA-- [141]
sc  --------------M------------------------------------STETTKPSITTTPTTV-----------------------------LVSPNTLKRKKGEDTSEEQLEA-E [40]
sc6 AIPTNNTNGGSS----------------------------------------------------------------------------------------------------DAGSAA-- [29]
at  --------------MV------------------------------------------------------------------------------------------------ERKKR--- [7]
at6 --------------MV------------------------------------------------------------------------------------------------ERGKRT-- [8]
                                                                                                                    :       

hs  --IMKLNGHQ---------LENHALKVSYIPDE---------QIAQGPE----NGRRGGFGSRGQPRQG--------SPVAAGAP-----AKQQQVD---IPLRLLVPTQYVGAIIGKEG [215]
mm  --IMKLNGHQ---------LENHALKVSYIPDE---------QITQGPE----NGRRGGFGSRGQPRQG--------SPVAAGAP-----AKQQPVD---IPLRLLVPTQYVGAIIGKEG [215]
rn  --IMKLNGHQ---------LENHALKVSYIPDE---------QIAQGPE----NGRRGGFGSRGQPRQG--------SPVAAGAP-----AKQQQVD---IPLRLLVPTQYVGAIIGKEG [215]
xt  --LEKLNGYQ---------LENYSLKVTYIPDEMATQQAPSQQLQQQPQQQHPQGRR-GFGQRGPARQG--------SP-GAAAR-----PKPQ-SE---VPLRMLVPTQFVGAIIGKEG [225]
dr  --IQKLNGYQ---------FDNNALRVSYIPDENS-----EVDSQRGPD----NGRRPGYGPRGTSRQM--------SP-GSGIP-----SKHQHAD---IPLRLLVPTQYVGAIIGKEG [218]
dm  --AVGLNGVE---------FEGSKLHAEQ-LDKNQ--------------------RR---SQRNQR-----------NP-YPGMP-----GPGRQAD---FPLRILVQSEMVGAIIGRQG [162]
ag  --VAGLNGVD---------FDGSKLLVEL-SDSNK------------------QARR---AQRNRS-----------QY-GAGMPGG--GGPGRQTD---FPLRVLVQSEMVGAIIGRQG [230]
ce  QQAQQMHQMQIHHQQHPQMMQQHAQQGYHPHQQNQQHQAGQHQQSHHQSQNHNQHRN-----HNQSHSG-----------PHHIPQNLMMPRCMLKD---WPIRCVVEGKYHAVIIGPNG [330]
is  --VAQLRDYE---------YEGSALKADYPMDPNN--------------------RN---GSRNNTRVGGRPPFRPFSY-SGNQP-----SPLRPSD---FPLRILVLSDMVGAIIGRAG [218]
sc  IKRVALKDAD--------------------------------------------------SHSDNDHDS-----------PDNVP----------SD---VHLRMLCLVKHASLIVGHKG [86]
sc6 --------------------------------------------------------------------------------TGGAP---VVGTTAQPT---INHRLLLSLKEAAKIIGTKG [63]
at  ---KQIQRNN--------------------SESNR-----------------NQKRR--ISHD----------------------------KI-NRDEL-VVYRILCPIDVVGGVIGKSG [55]
at6 --HNRFRDNN--------------------NDNNR-----------------NQRRR--LSYESEE------------------------KKIDNKDDLVVVYRILCPSGVMGSVIGKSG [63]
                                                                                                           * :      . ::*  *

hs  ATIRNITKQTQSKID---VHRKENA--GAAEKAISVHSTPEG--------------------CSSACKMILEIMHKEA---KDTKTAD--------------------EV---------- [277]
mm  ATIRNITKQTQSKID---VHRKENA--GAAEKAISVHSTPEG--------------------CSSACKMILEIMHKEA---KDTKTAD--------------------EV---------- [277]
rn  ATIRNITKQTQSKID---VHRKENA--GAAEKAISVHSTPEG--------------------CSSACKMILEIMHKEA---KDTKTAD--------------------EV---------- [277]
xt  ATIRNITKQTQSKID---IHRKENA--GAAEKPITIHSTPEG--------------------CSAACKIIMEIMQKEA---QDTKFTE--------------------EI---------- [287]
dr  ATIRNITKQTQSKID---VHRKENA--GAAEKPISIHSTPEG--------------------CSAACRMILEIMNQEA---KDTKTAD--------------------EV---------- [280]
dm  STIRTITQQSRARVD---VHRKENV--GSLEKSITIYGNPEN--------------------CTNACKRILEVMQQEA---ISTNKGEL--------------SPECSEI---------- [230]
ag  STIRHITQQSRARVD---VHRKDNV--GSVEKAITIYGNPEN--------------------CTMACKKILEVMQQEA---NSTNKG---------------------EI---------- [291]
ce  STIKDIASSTRCRVDFVNLSKKERTVLGNNDRILTVHGVAEQ--------------------ATKAVARILDVIQSEAV-KDDVNVGA--------------------DT---------- [399]
is  GTIRQITQQSRARVD---VHRKENA--GSLEKVITIYGNPEN--------------------CSTACQKILEVMQQEA---SNTNRG---------------------EV---------- [279]
sc  ATISRIKSETSARIN---ISNNIR---GVPERIVYVRGTCDD--------------------VAKAYGMIVRALLEEH---GNEDNGE-----------DI-------EI---------- [149]
sc6 STISRIRAANAVKIG---ISEKVP---GCSDRILSCAGNVIN--------------------VANAIGDIVDVLNKRNPENEDAAEGEAEEHYYFHFLNHILPAPSKDEIRDLQQLEDIG [157]
at  KVINAIRHNTKAKIK---VFDQLH---GCSQRVITIYCSVKEKQEEIGFTKSENE---PLCCAQDALLKVYDAIVASD---EENNTKT--------------------NV----DRDDNK [139]
at6 KVINLIRQETRARIK---VVDPFP---GCSERVITIFCSVSEKKDIVDIEYSELDYSVPLCSAQAALLKVHDAIVASL---ATAAENT--------------------KI----DRDDFR [150]
     .*  *   .  ::    :        *  :: :                               *   :   :                                  .           

hs  PLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISS-------LQDLTLYNP----ERTITVKG----------AIENCCRAEQEIMKKVREAYE------------------NDVA-A [357]
mm  PLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISS-------LQDLTLYNP----ERTITVKG----------AIENCCRAEQEIMKKVREAYE------------------NDVA-A [357]
rn  PLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISS-------LQDLTLYNP----ERTITVKG----------AIENCCRAEQEIMKKVREAYE------------------NDVA-A [357]
xt  PLKILAHNNFVGRLIGKEGRNLKKIEQDTDTKITISP-------LQDLTLYNP----ERTITVKG----------SIEACAKAEEEIMKKIRESYE------------------NDIA-A [367]
dr  PLKVLAHNNFVGRLIGKEGRNLKKVEQDTDTKITISP-------LQDLTLYNP----ERTITVKG----------SIEACCLAEQEIMKKVREAYD------------------NDIA-A [360]
dm  CLKILAHNNLIGRIIGKSGNTIKRIMQDTDTKITVSS-------INDINSFNL----ERIITVKG----------LIENMSRAENQISTKLRQSYE------------------NDLQ-A [310]
ag  CLKILAHNNLIGRIIGKSGNTIKRIMQDTDTKITVSS-------INDISSFNL----ERIITVKG----------SIENMSKGESQISAKLRQSYE------------------NDLQ-A [371]
ce  VLRMRAHNQLCGRLIGKAGSSIKEIMQKTGTNITVTKYIEPPGGISGLTANELLGLMERTIMVRG---------PSIEAVVQAEALISAKLKKCYE------------------SD-S-Q [490]
is  PLKILAHNNLIGRIIGKSGNTIKRIMEQTDTKITVSS-------LHDASTLNL----ERVITVKG----------KAEGVCRAEQLISAKLRQSYE------------------SDLA-A [359]
sc  SINLLIPHHLMGCIIGKRGSRLREIEDLSAAKLFASPNQLL---LSN----------DRILTINGVPDAI-----HIATFYISQTLLNFQMESPQK------------------NVKR-S [232]
sc6 YVRLIVANSHISSIIGKAGATIKSLINKHGVKIVASKDFLP---ASD----------ERIIEIQGFPGSITNVLIEISEIILSDVDVRFSTERSY------------------------- [239]
at  ECRLLVPFSQSSSLIGKAGENIKRIRRRTRASVKVVS-----KDVSDPSHVCAMEY-DNVVVISGEPE-------SVKQALFAVSAIMYKINPRENIPLDSTSQDVPAASVIVPSDLSNS [246]
at6 ECRLLVPSSQCSIVIGKSGSIIKNIRGRTRANVKVVS-----KDVSDPSHTCAMDF-DNIVMISGETE-------SVKKALFAVSAIMYKVSPREQIPLDTTVQEVP-ASIIIPSDL--S [254]
      .:       . :*** *  :: :     ..:             .          :. : : *                 .   :  .                              

hs  MSLQSHLIPGLN-L--------AAVGLFP---ASSSAV-----------------------PP---------------------PP-------SSVTGA-----------------APYS [397]
mm  MSLQSHLIPGLN-L--------AAVGLFP---ASSSAV-----------------------PP---------------------PP-------SSVTGA-----------------APYS [397]
rn  MSLQSHLIPGLN-L--------AAVGLFP---ASSSAV-----------------------PP---------------------PP-------SSVTGA-----------------APYG [397]
xt  MNLQAHLIPGLN-L--------NALGLFP---PSSSGM-----------------------PP---------------------PS----VGVPSPTTS-----------------TSYP [410]
dr  MNQQTHLIPGLN-L--------GAIGLFP----PSSAM-----------------------PP---------------------PA----LG-NSVPG------------------PPYG [400]
dm  MAPQSLMFPGLHPM--------AMMST------PGNGMVFN---------------TSMPFPSCQSFAMSKT------------PA------------------------------SVVP [359]
ag  LAPQTIMFPGLHPM--------AMMST------AGNGMGFTGRTAGATASASGSGATGM-YPG-SNFPMYQP------------PA-----GGP----------------------AGVP [436]
ce  LRAQSMQCP-MPPM--------MMPPILP----PGASS------------------SAVSAPH-------------------FIPTPVGVMQVQHFASSQHLVHQNANNSFLQPGVLQIQ [560]
is  LAPQTLMFPGLHPM--------TMMSTYP---PPGPPM--------------------RPQPHQHHQPMHHPQQPHQNARGGYYPSHHQGYGGPHHGGGGHLVY---------PNQGGAG [439]
sc  IYYQPTQFNSVL--------------------------------------------IDHSQPN----TIFHQRN-HQ-----YHPS---------------------------DKLLSYK [271]
sc6 -------FPHLK---------------------KSSGE-----------------------PT---------------S-----PS---------------------------------- [254]
at  VYPQTGFYSNQDHILQQGAGVPSYFNALSVSDFQGYAE-----------------TAANPVPV------------F-AS---SLPV-THGFG---------------------------- [304]
at6 IYPQAGLYPSQDSIFQHGANVSSFIGTLP----QGYGE-----------------NAANPVPV------------FSAS---ALPV-VHGFG---------------------------- [309]
                                                                 *                      *                                   

hs  SFMQAPEQEM-VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSK---------------------------------------------------VRMVIITGP-PEAQF [464]
mm  SFMQAPEQEM-VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSK---------------------------------------------------VRMVVITGP-PEAQF [464]
rn  SFMQAPEQEM-VQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSK---------------------------------------------------VRMVVITGP-PEAQF [464]
xt  PFGQQPESET-VHLFIPALAVGAIIGKQGQHIKQLSRFAGASIKIAPAEGPDAK---------------------------------------------------LRMVIITGP-PEAQF [477]
dr  P-MGASEQET-VHVYIPAQAVGALIGKKGQHIKQLSRFAGASIKIAPAEAPDSK---------------------------------------------------MRMVIVTGP-PEAQF [466]
dm  PVFPNDLQET-TYLYIPNNAVGAIIGTRGSHIRSIMRFSNASLKIAPLDADKPLDQQ-----------------------------------------------TERKVTIVGT-PEGQW [430]
ag  P-GSSEVQET-TYLYIPNNAVGAIIGTKGLHIRNIIRFSGASVKIAPLEADKPQEQQ-----------------------------------------------TERKVTIIGT-PEAQW [506]
ce  P-GTTNLRQ--VRMWVPDSMIGALIGAKGKNIKMIIRDTGASVKIEAPEEKTQREAEEAEKKRKLDETDSGCEGVASGDHPQEFLEDNATINSSDAIEEKPKPVSERMVTINGD-DLQLL [676]
is  P----DGREL-VYLYIPNVAVGAVIGTGGSSIRDMIMLSGASIKVAQPNRDDPADAH------------------------------------------------ERKVTIVGT-PESQW [505]
sc  PNKNLPISSTLLSMATPQ-------------------YTTASVANATAFQPN---------------------------------------------------FVIPNVTVLDG-PVISP [320]
sc6 --TSSNTR---IELKIPELYVGAIIGRGMNRIKNLKTFTKTNIVVERKDDDDKDE-------------------------------------------------NFRKFIITSKFPKNVK [320]
at  --GSSRSEELVFKVLCPLCNIMRVIGKGGSTIKRIREASGSCIEVNDSRTKCGDDE------------------------------------------------CVIIVTATES-PDD-- [371]
at6 --GSSRSEKLAIKVICSSSKIGRVIGKGGLTIKGIRQASGSHIEVNDSRTN-HDDD------------------------------------------------CVITVTATES-PDD-- [375]
                 :  .                     : : :                                                                 .           

hs  KAQGRIYGKLKEENFFGPKEEV--------KLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDEN----------DQVIVKIIGHFYASQMAQRKIRDILA-------- [558]
mm  KAQGRIYGKLKEENFFGPKEEV--------KLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDEN----------DQVIVKIIGHFYASQMAQRKIRDILA-------- [558]
rn  KAQGRIYGKLKEENFFGPKEEV--------KLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDEN----------DQVIVKIIGHFYASQMAQRKIRDILA-------- [558]
xt  KAQGRIYGKLKEENFFGPKEEV--------KLEAHIKVPSYAAGRVIGKGGKTVNELQNLTSAEVVVPRDQTPDEN----------DQVVVKITGHFYASQLAQRKIQEILA-------- [571]
dr  KAQGRIYGKLKEENFFGPKEEV--------KLETHIKVAAAAAGRVIGKGGKTVNELQNLTAAEVVVPREQTPDEH----------DQVIVKIIGHFYASQLAQRKIRDILT-------- [560]
dm  KAQYMIFEKMREEGFMCGTDDV--------RLTVELLVASSQVGRIIGKGGQNVRELQRVTGSVIKLPEHALAPPSG-------GDEETPVHIIGLFYSVQSAQRRIRAM---------- [525]
ag  KAQYLIFEKMREEGFVSGTDDV--------RLTVEIFVPSAQVGRIIGKGGQNVRELQRVTGSIIKLPEHTASAPV---------DEETTVHIIGPFFSVQSAQRRIRTM---------- [599]
ce  KAQSYVFSKIAETSSSLPSSGMDGDRSHMLRIRTEVSVPTRIIGRIIGKGGQNVRELQRITGAVVKIPEEERNGGEVYRHDDGLEEDMTMIRTIGNMYSTHNVQFRLAHLVNE------- [789]
is  RAQGMIFNKVCYEG-CAGSQDG--------TLRVEIFVPSNQVGRIIGKGGQTVRELQRLTRALIKLPDESQNANS----------EETPVHILGEFFSSQAAQRQIRALVSRN-----Q [601]
sc  APGNHLLMNFVQQ---------------------EIFIDEKFVGNVIGKDGKHINSVKESTGCSIIIQDPVEGSSE----------RRLTIR--GTFMASQAAIMLISNKIE-------- [399]
sc6 LAESMLLKNLNTE---------------------------------IEKRENYKRKLEAAEG------------------------DATVV----------------------------- [354]
at  ------MKSMAVEAVLLLQEYINDEDAE--NVKMQLLVSSKVIGCVIGKSGSVINEIRKRTNANICISKGK---------------KDDLVEVSGEVSSVRDALIQIVLRLREDVLGDKD [468]
at6 ------LKSMAVEAVLLLQEKINDEDED--KVKMQLLVSSKVIGCIIGKSGSIISEIRKRTKADIHISKGNNTPKCA-------DPNDELVEISGEVSNVRDALIQIVLRLRDDVLRDRE [480]
            ..                                    * *  .   .:.                                :                             

hs  --------------------QVKQQHQKG------------------------------------------------------------------------------------------- [567]
mm  --------------------QVKQQHQKG------------------------------------------------------------------------------------------- [567]
rn  --------------------QVKQQHQKG------------------------------------------------------------------------------------------- [567]
xt  --------------------QVRRQQQQQ------------------------------------------------------------------------------------------- [580]
dr  --------------------QVKQQQKGGGMG-------------------------------------------------------------------TPQGPHPQGMT---------- [583]
dm  MLSTNPPPITKKQKAAKEQLQQQQQSLAGAASSGSQQQQ------------PQSPSQQQALPPQLHHQPVSSASSSSTPPAHHQQQASTAATSHQLQQQQPSPPPPGNAT---------- [623]
ag  MLATNPPPVTKRQTSQK----AKDQTTGGATT------------------------------------PAAGATAATT---------TTAAVT--------TTPP--------------- [647]
ce  ---------YYRSGDHR---NKSSDYKGGRPHSA----------------------------------PSSGQEKDGSALEKMDQLGTIAPISN----SNRASPK--------------- [844]
is  MAGQQPYPMHPRSNNNN----GPRRNVSGEPR------------------------------------------GNNGPPA-----------------RRPSPPS--------------- [643]
sc  ---------IDRSNAER----------------------------------------------------------------------------------KRRSPL--------------- [413]
sc6 ---------TERSDSAS-------------------------------------------------------------------------------FLEEKEEPQENH------------ [374]
at  SVATRKPP--ARTDNCS--FL-SGSSNAGYTLP-SFMSS---------------------MA------STSGFHGYGSFPAGDNVLGSTGPYS------YGRLPSSSALEILIPAHAMSK [549]
at6 TGSRNQPP--ARSENNN--FFSSSSSNTGLALPQSFMSSVPQVASVDFNRRPETGSSMSMLP------SSGGIYGYGSFPVGNTSYGSNSSYSSN---LYGGLPQSTTMEVRIPANAVGK [587]
                                                                                                                            

hs  --------------------------------------------------------------------------------------QSNQAQARRK------ [577]
mm  --------------------------------------------------------------------------------------QSNLAQARRK------ [577]
rn  --------------------------------------------------------------------------------------QSNQAQARRK------ [577]
xt  ----------------------------------------------------------------------------------QKTAQSGQPQPRRK------ [594]
dr  ---------------------------------------------------------------------------------ELGSPQGLAQEPRRK------ [598]
dm  ------------------------------------------------------------------------------AAAAQQQQQLASSQQ--------- [638]
ag  ------------------------------------------------------------------------------------QQQSSSTNA--------- [656]
ce  ---------------------------------------------------------------------------------SVSPPKSKSP----------- [854]
is  ---------------------------------------------------------------------------------AAHDSQGGSQDSN-------- [656]
sc  ------------------------------------------------------------------------------------------------------ [413]
sc6 ---------------------------------------------------------------------------------DNKEEQS-------------- [381]
at  VMGKGGGNLENIRR---------------------------------------------ISGAMIEISASKTSHGDHIALLSGTLEQMRCAENLVQAFVMST [606]
at6 VMGRGGGNLDNIRRVCLIFIFIFPSSLLSDCHSFIRLFFPLSYITFSHGMCPLSLSLSQISGAMIEISDSKNSHGGRVALISGTSEQKRTAENLFQAFIMST [689]
                                                                                                          


Alignment Details

Alignment done with MAFFT FFT-NS-2 (v7.305b) aligner. MAFFT References
  • Strategy: Auto
  • Scoring Matrix: BLOSUM62
  • Gap Penalty: 1.53
  • Offset Value: 0.0