Welcome to the Drosophila RNAi Screening Center (DRSC) at Harvard Medical School. The DRSC allows researchers in the Harvard community and beyond to perform genome-scale and sub-library RNAi and related Drosophila cell-based screens. Researchers from the U.S. and abroad have been screening at the DRSC since 2003 and an impressive list of publications has resulted from work performed here and followed-up at the home institution.

Genome-Wide RNAi and other Libraries

The DRSC supports whole-genome screens on-site (4-8 weeks). In addition, we provide on-site visits for screen optimization (2-3 weeks) support screening of the specialized sub-libraries on- or off-site.

Several Assay Types Supported

The DRSC supports several assay types, including fluorescent or luminescent quantitation; one- or two-color in-cell westerns and cell-to-protein normalization; and multi-channel, high-content confocal fluorescent imaging.

Getting Started

Interested in performing a screen? We urge you to read *** and visit *** to view an overview of the screening process. Researchers ready to apply for on-site visits will need to submit an Application Form.