Protein Alignment SCO2 and SCO1

DIOPT Version :10

• Sequence 1: NP_005129.2
• Gene: SCO2 / 9997
• HGNCID: 10604
• Length: 266
• Species: Homo sapiens
• Sequence 2: NP_009593.1
• Gene: SCO1 / 852325
• SGDID: S000000241
• Length: 295
• Species: Saccharomyces cerevisiae
• Alignment Length: 288
• Identity: 102/288 - (35%)
• Similarity: 147/288 - (51%)
• Gaps: 39/288 - (13%)

Human     1 MLLLTRSPTAWHRLSQLKPRVLPGTLGGQALHLRSWLLSRQGPAETGGQGQPQGPGLRTRLLITG 65
            ||.|:||...  ||.||....|.|. |.:       ||:::|........|..|....:|:.:.|
Yeast     1 MLKLSRSANL--RLVQLPAARLSGN-GAK-------LLTQRGFFTVTRLWQSNGKKPLSRVPVGG 55

Human    66 L--------------FGAG--------LGGAW-LALRAEKERLQQQKRTEALR---QAAVGQGDF 104
            .              |..|        :|||. .....||.||:.||..||.|   :.::| |.|
Yeast    56 TPIKDNGKVREGSIEFSTGKAIALFLAVGGALSYFFNREKRRLETQKEAEANRGYGKPSLG-GPF 119

Human   105 HLLDHRGRARCKADFRGQWVLMYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDP 169
            ||.|..|....:.:..|::.::||||::|||||||||:||...:..|.::.|: .:||:|||.||
Yeast   120 HLEDMYGNEFTEKNLLGKFSIIYFGFSNCPDICPDELDKLGLWLNTLSSKYGI-TLQPLFITCDP 183

Human   170 ERDDVEAMARYVQDFHPRLLGLTGSTKQVAQASHSYRVYYNAGPK-DEDQDYIVDHSIAIYLLNP 233
            .||....:..|:.||||.:|||||:..:|..|...||||::..|. ...|||:|||||..||::|
Yeast   184 ARDSPAVLKEYLSDFHPSILGLTGTFDEVKNACKKYRVYFSTPPNVKPGQDYLVDHSIFFYLMDP 248

Human   234 DGLFTDYYGRSRSAEQISDSVRRHMAAF 261
            :|.|.|..||:...:...|.:..|:.::
Yeast   249 EGQFVDALGRNYDEKTGVDKIVEHVKSY 276

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCO2	NP_005129.2	SCO	101..242	CDD:239266	64/141 (45%)
SCO1	NP_009593.1	SCO	115..257	CDD:239266	65/143 (45%)