Protein Alignment SCO2 and Scox

DIOPT Version :10

• Sequence 1: NP_005129.2
• Gene: SCO2 / 9997
• HGNCID: 10604
• Length: 266
• Species: Homo sapiens
• Sequence 2: NP_608884.1
• Gene: Scox / 33711
• FlyBaseID: FBgn0262467
• Length: 251
• Species: Drosophila melanogaster
• Alignment Length: 240
• Identity: 112/240 - (46%)
• Similarity: 158/240 - (65%)
• Gaps: 17/240 - (7%)

Human    34 RSWLLSRQGPA---------ETGGQGQPQGPGLRTRLLITGLFGAGLGGAWLALRAEKERLQQQK 89
            |.|   .|.||         .|.|    :||.....|.:.|..|||..|..|.:::||:..:.::
  Fly    13 RRW---AQQPAIRHYAAPADSTKG----KGPISWRSLAVIGALGAGGVGFMLYVKSEKDEARMKE 70

Human    90 RTEALRQAAVGQGDFHLLDHRGRARCKADFRGQWVLMYFGFTHCPDICPDELEKLVQVVRQLEAE 154
            |...|.:||:| |.:.|:|.:|..|...||.|:|:|:|||||||||||||||||:..||.::|..
  Fly    71 RQRQLGKAAIG-GSWELVDSQGAVRKSEDFLGKWLLIYFGFTHCPDICPDELEKMAAVVDEVEKS 134

Human   155 PGLPPVQPVFITVDPERDDVEAMARYVQDFHPRLLGLTGSTKQVAQASHSYRVYYNAGPKDEDQD 219
            |..|.|||:|||||||||..|.:|:||::|.|:||||||:.:|:.:...::|||::|||:|||.|
  Fly   135 PQTPAVQPIFITVDPERDSKEVVAKYVKEFSPKLLGLTGTVEQIRKVCKAFRVYFSAGPRDEDND 199

Human   220 YIVDHSIAIYLLNPDGLFTDYYGRSRSAEQISDSVRRHMAAFRSV 264
            |||||:|.:||:||||.|.||||::|..:|...|:..::|.:.|:
  Fly   200 YIVDHTIIMYLVNPDGEFVDYYGQNRDKDQCVASILVNIAKWNSM 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCO2	NP_005129.2	SCO	101..242	CDD:239266	82/140 (59%)
Scox	NP_608884.1	SCO1-SenC	81..217	CDD:460630	80/136 (59%)