Protein Alignment SCO2 and sco-1

DIOPT Version :10

• Sequence 1: NP_005129.2
• Gene: SCO2 / 9997
• HGNCID: 10604
• Length: 266
• Species: Homo sapiens
• Sequence 2: NP_494755.1
• Gene: sco-1 / 173763
• WormBaseID: WBGene00015297
• Length: 312
• Species: Caenorhabditis elegans
• Alignment Length: 208
• Identity: 88/208 - (42%)
• Similarity: 138/208 - (66%)
• Gaps: 11/208 - (5%)

Human    63 ITGLFGAGLGGAWLA--LRAEKERLQQQK--RTEALRQAAVGQGDFHLLDHRGRARCKADFRGQW 123
            :.|.|  .:||..||  ...:|.||.:::  |.:...:|.:| |::.|::..|:.....:.||.|
 Worm    99 VLGTF--AVGGTCLAALFYIKKIRLDEREKHRKQTAGKARIG-GEWELMNTDGKMEGSQELRGNW 160

Human   124 VLMYFGFTHCPDICPDELEKLVQVVRQLEAEPGLPPVQPVFITVDPERDDVEAMARYVQDFHPRL 188
            :|||||||:||||||||:||:|:||..:||:....|:.||||:||||||.|..:..|..:|..:|
 Worm   161 LLMYFGFTNCPDICPDEIEKMVKVVEIIEAKKDATPIVPVFISVDPERDSVARVKEYCSEFSNKL 225

Human   189 LGLTGSTKQVAQASHSYRVYYNAGP---KDEDQDYIVDHSIAIYLLNPDGLFTDYYGRSRSAEQI 250
            .|.||:|:||.:.:.::|||::.||   |.|| ||||||::.:||::|.|.|.||||::|.||:|
 Worm   226 RGFTGTTEQVNKVAKTFRVYHSQGPRTNKQED-DYIVDHTVIMYLIDPSGQFHDYYGQNRKAEEI 289

Human   251 SDSVRRHMAAFRS 263
            ::.:...:..:::
 Worm   290 ANVIEMKVLKYQA 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCO2	NP_005129.2	SCO	101..242	CDD:239266	70/143 (49%)
sco-1	NP_494755.1	SCO1-SenC	138..276	CDD:460630	68/139 (49%)