Protein Alignment HNRNPDL and Hnrnpdl

DIOPT Version :10

• Sequence 1: NP_112740.1
• Gene: HNRNPDL / 9987
• HGNCID: 5037
• Length: 420
• Species: Homo sapiens
• Sequence 2: NP_057899.2
• Gene: Hnrnpdl / 50926
• MGIID: 1355299
• Length: 420
• Species: Mus musculus
• Alignment Length: 420
• Identity: 408/420 - (97%)
• Similarity: 411/420 - (97%)
• Gaps: 0/420 - (0%)

Human     1 MEVPPRLSHVPPPLFPSAPATLASRSLSHWRPRPPRQLAPLLPSLAPSSARQGARRAQRHVTAQQ 65
            |||||||||||||||||||||||||.|||||||.||||||||||||.|::||||||:.|||||||
Mouse     1 MEVPPRLSHVPPPLFPSAPATLASRGLSHWRPRAPRQLAPLLPSLASSASRQGARRSPRHVTAQQ 65

Human    66 PSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRTARQHPPADSSVTMEDMNEYSNIE 130
            ||||||||||||||||||||||||||||||||||||||.||||||||.||.|.||||||||||||
Mouse    66 PSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAGTRTARQHPLADGSATMEDMNEYSNIE 130

Human   131 EFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVL 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 EFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVL 195

Human   196 FKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIE 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   196 FKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIE 260

Human   261 NIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGR 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   261 NIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGR 325

Human   326 GAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYG 390
            |||||||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   326 GAAAGGRGGARGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYG 390

Human   391 QGYADYSGQQSTYGKASRGGGNHQNNYQPY 420
            ||||||||||||||||||||||||||||||
Mouse   391 QGYADYSGQQSTYGKASRGGGNHQNNYQPY 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HNRNPDL	NP_112740.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..83		74/81 (91%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	96..120		19/23 (83%)
		RRM1_hnRPDL	149..224	CDD:410152	74/74 (100%)
		RRM2_hnRPDL	234..308	CDD:409998	73/73 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	313..348		33/34 (97%)
		Necessary for interaction with TNPO1. /evidence=ECO:0000269|PubMed:9524220	342..420		77/77 (100%)
		Necessary for its nuclear import and export	396..420		23/23 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	398..420		21/21 (100%)
Hnrnpdl	NP_057899.2	RRM1_hnRPDL	149..224	CDD:410152	74/74 (100%)
		RRM2_hnRPDL	234..308	CDD:409998	73/73 (100%)