DRSC/TRiP Functional Genomics Resources

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Protein Alignment HNRNPDL and hnrnpdl

DIOPT Version :10

Sequence 1:NP_112740.1 Gene:HNRNPDL / 9987 HGNCID:5037 Length:420 Species:Homo sapiens
Sequence 2:NP_001011015.1 Gene:hnrnpdl / 496424 XenbaseID:XB-GENE-495016 Length:297 Species:Xenopus tropicalis


Alignment Length:302 Identity:256/302 - (84%)
Similarity:272/302 - (90%) Gaps:9/302 - (2%)


- Green bases have known domain annotations that are detailed below.


Human   123 MNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGR 187
            |..:....:|.|||||||||||||:||||||||||||||||||||||||||||||||||||||||
 Frog     1 MTGFGATPDFNEGSKINASKNQQDEGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGR 65

Human   188 SRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEY 252
            ||||||||||||.|||||||.||||||||||||||||||||||||||||||||||:|:|||||:|
 Frog    66 SRGFGFVLFKDAVSVDKVLETKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPETTEEQIKQY 130

Human   253 FGAFGEIENIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQ 317
            ||.|||||||||||||||||||||||:|||.|||||||||||:||||:|||||||||||||||||
 Frog   131 FGGFGEIENIELPMDTKTNERRGFCFVTYTGEEPVKKLLESRFHQIGTGKCEIKVAQPKEVYRQQ 195

Human   318 QQ-QQKGGRGAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGNY--NSAYGGDQNY-SGYGGYD 378
            || |||||||||. ||||.||||||||  ||||::|||||.||:|  |.:| .||.| :.|.|||
 Frog   196 QQKQQKGGRGAAT-GRGGARGRGRGQG--WNQGYSNYYDQNYGSYGNNGSY-ADQGYNNSYSGYD 256

Human   379 YTGYNYGNYGYGQGYADYSGQQSTYGKASRGGGNHQNNYQPY 420
            |:|||||:|||.|||.|||||||||||| |||||||||||||
 Frog   257 YSGYNYGSYGYNQGYTDYSGQQSTYGKA-RGGGNHQNNYQPY 297

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HNRNPDLNP_112740.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..83
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 96..120
RRM1_hnRPDL 149..224 CDD:410152 72/74 (97%)
RRM2_hnRPDL 234..308 CDD:409998 65/73 (89%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 313..348 29/35 (83%)
Necessary for interaction with TNPO1. /evidence=ECO:0000269|PubMed:9524220 342..420 58/80 (73%)
Necessary for its nuclear import and export 396..420 22/23 (96%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 398..420 20/21 (95%)
hnrnpdlNP_001011015.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..21 10/19 (53%)
RRM1_hnRPDL 27..102 CDD:410152 72/74 (97%)
RRM2_hnRPDL 112..186 CDD:409998 65/73 (89%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 192..224 28/34 (82%)
Trnau1ap 223..>272 CDD:465438 31/49 (63%)
Blue background indicates that the domain is not in the aligned region.

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