Protein Alignment HNRNPDL and CG10466

DIOPT Version :10

• Sequence 1: NP_112740.1
• Gene: HNRNPDL / 9987
• HGNCID: 5037
• Length: 420
• Species: Homo sapiens
• Sequence 2: NP_610003.1
• Gene: CG10466 / 35268
• FlyBaseID: FBgn0032822
• Length: 154
• Species: Drosophila melanogaster
• Alignment Length: 148
• Identity: 39/148 - (26%)
• Similarity: 68/148 - (45%)
• Gaps: 24/148 - (16%)

Human   123 MNEYSNIE--------EFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTI 179
            ||..:|::        |...|.|.:.....:|...:|:.|..:..::.||....|::||||:..:
  Fly     1 MNPLTNMKNVLKLSEHELQHGGKKSWHDMYKDSAWIFVAGFPYTLTEGDLVCVFSQYGEVVNINL 65

Human   180 KTDPVTGRSRGFGFVLFKDAAS----VDKVLELK--------EHKLDGKLIDPKRAKALKGKEPP 232
            ..|..||:|:||.|:.::|..|    ||.:..:|        :|..|.|  .||..:  |..|..
  Fly    66 IRDSKTGKSKGFCFLCYEDQRSTVLAVDNLNGIKILDRTLRVDHVADYK--PPKENE--KMDEET 126

Human   233 KKVFVGGLSPDTSEEQIK 250
            .::::.|.:|....:.||
  Fly   127 LRLYMEGCAPKPQLQHIK 144

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HNRNPDL	NP_112740.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..83
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	96..120
		RRM1_hnRPDL	149..224	CDD:410152	26/86 (30%)
		RRM2_hnRPDL	234..308	CDD:409998	4/17 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	313..348
		Necessary for interaction with TNPO1. /evidence=ECO:0000269|PubMed:9524220	342..420
		Necessary for its nuclear import and export	396..420
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	398..420
CG10466	NP_610003.1	RRM_ist3_like	25..113	CDD:409845	23/87 (26%)