Protein Alignment HNRNPDL and Hnrnpdl

DIOPT Version :10

• Sequence 1: NP_112740.1
• Gene: HNRNPDL / 9987
• HGNCID: 5037
• Length: 420
• Species: Homo sapiens
• Sequence 2: XP_063129121.1
• Gene: Hnrnpdl / 305178
• RGDID: 1309950
• Length: 428
• Species: Rattus norvegicus
• Alignment Length: 401
• Identity: 383/401 - (95%)
• Similarity: 389/401 - (97%)
• Gaps: 1/401 - (0%)

Human     1 MEVPPRLSHVPPPLFPSAPATLASRSLSHWRPRPPRQLAPLLPSLAPSSARQGARRAQRHVTAQQ 65
            |||||||||||||||||||||||||||||||||.||||||||||||.||:||||||.||||||||
  Rat     1 MEVPPRLSHVPPPLFPSAPATLASRSLSHWRPRAPRQLAPLLPSLASSSSRQGARRTQRHVTAQQ 65

Human    66 PSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAAATRTARQHPPADSSVTMEDMNEYSNIE 130
            |||||||||||||||||||||||||||||||||||||..||||||||.||.|.||||||||||||
  Rat    66 PSRLAGGAAIKGGRRRRPDLFRRHFKSSSIQRSAAAAPGTRTARQHPLADGSATMEDMNEYSNIE 130

Human   131 EFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVL 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 EFAEGSKINASKNQQDDGKMFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVL 195

Human   196 FKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIE 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 FKDAASVDKVLELKEHKLDGKLIDPKRAKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIE 260

Human   261 NIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGR 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   261 NIELPMDTKTNERRGFCFITYTDEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGR 325

Human   326 GAAAGGRGGTRGRGRGQGQNWNQGFNNYYDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYG 390
            |||||||||.|||||||||||||||||||||||||||||| ||::|||||||||||||||:||||
  Rat   326 GAAAGGRGGARGRGRGQGQNWNQGFNNYYDQGYGNYNSAY-GDESYSGYGGYDYTGYNYGSYGYG 389

Human   391 QGYADYSGQQS 401
            |||.||||:.:
  Rat   390 QGYTDYSGKST 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HNRNPDL	NP_112740.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..83		77/81 (95%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	96..120		18/23 (78%)
		RRM1_hnRPDL	149..224	CDD:410152	74/74 (100%)
		RRM2_hnRPDL	234..308	CDD:409998	73/73 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	313..348		33/34 (97%)
		Necessary for interaction with TNPO1. /evidence=ECO:0000269|PubMed:9524220	342..420		52/60 (87%)
		Necessary for its nuclear import and export	396..420		3/6 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	398..420		1/4 (25%)
Hnrnpdl	XP_063129121.1	None