Protein Alignment CDC42 and Rac2

DIOPT Version :10

• Sequence 1: NP_001782.1
• Gene: CDC42 / 998
• HGNCID: 1736
• Length: 191
• Species: Homo sapiens
• Sequence 2: NP_648121.1
• Gene: Rac2 / 38831
• FlyBaseID: FBgn0014011
• Length: 192
• Species: Drosophila melanogaster
• Alignment Length: 193
• Identity: 131/193 - (67%)
• Similarity: 153/193 - (79%)
• Gaps: 3/193 - (1%)

Human     1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYD 65
            ||.|||||||||||||||||||||||.||.||:|||||||:..||:..:|..|||:|||||||||
  Fly     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYD 65

Human    66 RLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLA 130
            ||||||||||||||:|||:|:|:|||||:.||.||:.||||..|.:||||::|||||..|||||.
  Fly    66 RLRPLSYPQTDVFLICFSLVNPASFENVRAKWFPEVRHHCPSVPIILVGTKLDLRDDKQTIEKLK 130

Human   131 KNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEP--PEPKKSRRCVLL 191
            ..|..|||......:|:::.||||:|||||||||||.||||||.:.|.|  ..||: .:|.||
  Fly   131 DKKLTPITYPQGLAMAKEIAAVKYLECSALTQKGLKTVFDEAIRSVLCPVVRGPKR-HKCALL 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDC42	NP_001782.1	Cdc42	3..177	CDD:206664	122/173 (71%)
		Effector region. /evidence=ECO:0000255	32..40		6/7 (86%)
Rac2	NP_648121.1	Rac1_like	3..176	CDD:206663	122/172 (71%)