Protein Alignment CDC42 and Rho1

DIOPT Version :10

• Sequence 1: NP_001782.1
• Gene: CDC42 / 998
• HGNCID: 1736
• Length: 191
• Species: Homo sapiens
• Sequence 2: NP_477098.1
• Gene: Rho1 / 36775
• FlyBaseID: FBgn0014020
• Length: 192
• Species: Drosophila melanogaster
• Alignment Length: 193
• Identity: 106/193 - (54%)
• Similarity: 140/193 - (72%)
• Gaps: 3/193 - (1%)

Human     1 MQTI--KCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQED 63
            |.||  |.|:|||||.|||||||.::.::||..||||||:||...:.:.|:...|.|:|||||||
  Fly     1 MTTIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQED 65

Human    64 YDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEK 128
            ||||||||||.|||.|:||||.||.|.||:.|||.||:.|.||..|.:|||.:.|||:||:||..
  Fly    66 YDRLRPLSYPDTDVILMCFSVDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDPNTIRD 130

Human   129 LAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL 191
            |||.||:|:.|:....:|..:.|..|:||||.:::|:::||:.|..|||:..:.||: ||:||
  Fly   131 LAKMKQEPVKPQEGRAMAEKINAFAYLECSAKSKEGVRDVFETATRAALQVKKRKKT-RCLLL 192

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDC42	NP_001782.1	Cdc42	3..177	CDD:206664	97/175 (55%)
		Effector region. /evidence=ECO:0000255	32..40		6/7 (86%)
Rho1	NP_477098.1	RhoA_like	5..179	CDD:206662	95/173 (55%)