DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CDC34 and CG17030

DIOPT Version :9

Sequence 1:	XP_005259747.1	Gene:	CDC34 / 997	HGNCID:	1734	Length:	269	Species:	Homo sapiens
Sequence 2:	NP_647941.1	Gene:	CG17030 / 38591	FlyBaseID:	FBgn0035584	Length:	180	Species:	Drosophila melanogaster

Alignment Length:	187	Identity:	50/187 - (26%)
Similarity:	83/187 - (44%)	Gaps:	39/187 - (20%)

- Green bases have known domain annotations that are detailed below.

Human     1 MARPLVPSSQKALLLELK-GLQEEPVEGFRVTLVDEGDLYNWEVAIF--GPPNTYYEGGYFKARL 62
            |..|...:.:.||:||.| .||      ||..||:..::|.|...:.  .||   |:.|.:|..:
  Fly     9 MDGPKRMNRELALMLEDKQNLQ------FRNLLVEPNNIYKWTGLLMPVAPP---YDKGAYKMEI 64

Human    63 KFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSV 127
            .||:|||:.||.....|:|:|.|:.|.|.||:.||.            .|.|.||..:..:|..:
  Fly    65 DFPLDYPFKPPRIHINTRMYHLNVNERGQVCVPILE------------VEHWIPTTRIDQVLQVL 117

Human   128 ISLLNEPNTFSPANVDASVMYR---------------KWKESKGKDREYTDIIRTQE 169
            ::.:|:|...:..:::.:..||               |:.|.:..:.|.....|.::
  Fly   118 LATINDPQPENAWHIEMAGEYRNDPVRFFKMADAWVQKYSEPRPTEEELAKFARKRK 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CDC34	XP_005259747.1	COG5078	6..162	CDD:227410	47/173 (27%)
CDC34	XP_005259747.1	UBCc	11..162	CDD:238117	47/168 (28%)
CG17030	NP_647941.1	COG5078	12..158	CDD:227410	46/166 (28%)
CG17030	NP_647941.1	UQ_con	14..153	CDD:278603	44/159 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910