Protein Alignment CDC25C and stg

DIOPT Version :10

• Sequence 1: NP_001274512.1
• Gene: CDC25C / 995
• HGNCID: 1727
• Length: 551
• Species: Homo sapiens
• Sequence 2: NP_524547.1
• Gene: stg / 43466
• FlyBaseID: FBgn0003525
• Length: 479
• Species: Drosophila melanogaster
• Alignment Length: 519
• Identity: 158/519 - (30%)
• Similarity: 227/519 - (43%)
• Gaps: 123/519 - (23%)

Human    74 ENSKTMSTELFSSTREEGS----SGSGPSFRSNQRKMLNLLLERDTSF----TVCPDVPRTPVGK 130
            ||:.:|...:.::|....|    |||..:.||.:...::   :.:.||    .|..|..|:...:
  Fly     9 ENNCSMDCNISNNTSSSSSINKMSGSRRARRSLELMSMD---QEELSFYDDDVVPQDQQRSASPE 70

Human   131 FLGDSANLSILS-GGTPKR--------CLDLSNLSSGEITATQLTTSADLDETGHLDSSGLQEVH 186
            .:|      :|| .|:|:|        .|....:||....|........|..|..::||
  Fly    71 LMG------LLSPEGSPQRFQIVRQPKILPAMGVSSDHTPARSFRIFNSLSSTCSMESS------ 123

Human   187 LAGMNHDQHL----MKCSPAQLLCSTPNGLD---RGHRKRDAMCSS---------------SANK 229
                ..|:::    |:....|.....|:||:   .|..|......|               |..:
  Fly   124 ----MDDEYMELFEMESQSQQTALGFPSGLNSLISGQIKEQPAAKSPAGLSMRRPSVRRCLSMTE 184

Human   230 ENDNGNLVDSEMKYLGSPITTVPKLDKNPNLGEDQAEEISDELMEFSLKDQEAKVSRSGLYRSPS 294
            .|.|.              ||.|. .|.|....|                         .::.|.
  Fly   185 SNTNS--------------TTTPP-PKTPETARD-------------------------CFKRPE 209

Human   295 MPENLN-------RPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGLCLKKTVSLCDITITQML- 351
            .|.:.|       |.|...||| ::...|..:.:...|....|||  |:    ||.|..|...|
  Fly   210 PPASANCSPIQSKRHRCAAVEK-ENCPAPSPLSQVTISHPPPLRK--CM----SLNDAEIMSALA 267

Human   352 -EEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYL 415
             .|:.|:..|||||||..|||.:.|:|:|||.::.||||.||.|:|...:..:.:||||||||:.
  Fly   268 RSENRNEPELIGDFSKAYALPLMEGRHRDLKSISSETVARLLKGEFSDKVASYRIIDCRYPYEFE 332

Human   416 GGHIQGALNLYSQEELFNFFLKKPIVPLDTQ-------KRIIIVFHCEFSSERGPRMCRCLR--E 471
            ||||:||.|||:.|::.:.||......|..|       ||.||:|||||||||||:|.|.||  :
  Fly   333 GGHIEGAKNLYTTEQILDEFLTVQQTELQQQQNAESGHKRNIIIFHCEFSSERGPKMSRFLRNLD 397

Human   472 EDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMHHQDHKTELLRCRSQSKVQEGE 535
            .:|:.|.||||:|||:|:|..||::||..::|||||.:|..|....:.......|::||...|:
  Fly   398 RERNTNAYPALHYPEIYLLHNGYKEFFESHVELCEPHAYRTMLDPAYNEAYRHFRAKSKSWNGD 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDC25C	NP_001274512.1	MIH1	<285..525	CDD:227436	107/257 (42%)
		Cdc25	380..499	CDD:238788	65/127 (51%)
stg	NP_524547.1	Cdc25	297..425	CDD:238788	65/127 (51%)