DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MAGEC1 and MAGE

DIOPT Version :9

Sequence 1:	NP_005453.2	Gene:	MAGEC1 / 9947	HGNCID:	6812	Length:	1142	Species:	Homo sapiens
Sequence 2:	NP_649702.2	Gene:	MAGE / 40860	FlyBaseID:	FBgn0037481	Length:	232	Species:	Drosophila melanogaster

Alignment Length:	250	Identity:	59/250 - (23%)
Similarity:	97/250 - (38%)	Gaps:	65/250 - (26%)

- Green bases have known domain annotations that are detailed below.

Human   868 SEESSSPVDEYTSSSDTLLESDSLTDSESLIESEPLFTYTLDEKVDELARFLLLKYQVKQPITKA 932
            |:|:..|||                              .:|.||..:..::|.....|.||...
  Fly    16 SQEAQQPVD------------------------------VVDAKVRAILNYILDHTAQKIPIKDK 50

Human   933 EML--TNVISRYTGYFPVIFRKAREFIEILFGISLREVDPDDSYVFVNTLDLTSEGCLSDEQGMS 995
            :::  ....|......|::.....|    .|||.|..:|. .:..|:         |.::|...|
  Fly    51 DLIAVAGDKSELKKRLPLVTNLLAE----TFGIILTPLDA-TTKTFI---------CTAEEPVAS 101

Human   996 ----------QNRLLILILSIIFIKGTYASEEVIWDVLSGIGVRAGREHFAFG-EPRELLTKVWV 1049
                      |..||.:||..||::|....:..::.:|..:.:....||..|| ..|:.:.:.:|
  Fly   102 IHELTPAQRPQFTLLYIILMYIFLRGNRIEDSKLYVMLEMLNIYPDEEHGYFGPNLRKQIEETFV 166

Human  1050 QEHYLEYREVPNSSPPRYE-----FLWGPRAHSEVIKRKVVEFLAMLKNTVPITF 1099
            ::.||: ||  .|....|:     |||||||.:|....::|:|.:.|.|..|..|
  Fly   167 KQQYLK-RE--RSQLSAYDDSKTFFLWGPRAKAEFTFEQMVQFASKLLNQHPKVF 218

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MAGEC1	NP_005453.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..132
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	502..778
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	791..893		5/24 (21%)
		MAGE	915..1082	CDD:279759	45/184 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1118..1142
MAGE	NP_649702.2	MAGE	36..201	CDD:279759	45/181 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151975
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4562
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1195799at2759
OrthoFinder	1	1.000	-	-		FOG0000171
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11736
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.940