Protein Alignment IQSEC1 and Sec71

DIOPT Version :10

• Sequence 1: NP_001363867.1
• Gene: IQSEC1 / 9922
• HGNCID: 29112
• Length: 1222
• Species: Homo sapiens
• Sequence 2: NP_609675.2
• Gene: Sec71 / 34785
• FlyBaseID: FBgn0028538
• Length: 1653
• Species: Drosophila melanogaster
• Alignment Length: 320
• Identity: 59/320 - (18%)
• Similarity: 94/320 - (29%)
• Gaps: 133/320 - (41%)

Human   194 LNFGMADPTQMGGLSMLLLAGEHALGTPEASSGTCRP--------DISESPE------------- 237
            ||.|  ||.|                ||..::|||.|        .|.:||:
  Fly    25 LNSG--DPCQ----------------TPSGTAGTCEPVKNCSYVRKILKSPDFSHYDTTYLDTLK 71

Human   238 -------LRQK------SPLFQ---------------FAEISSRTSHPDAPSKQCQASALFQFAE 274
                   :|:|      .|.|.               |.|.:.|.:||       .|:.||.
  Fly    72 CGDLMVPMRKKPIPLLCCPKFSNSPTCGAQQLADRIYFGEETERGAHP-------WAALLFY--- 126

Human   275 ISSSTSQLGGTEPVKRCGNSALFQLAEMCLASEGVKMEDTKLIKSKESDGGRIEEIEKGKEERGT 339
                  .:|....|.:||.:.:.:...:..|...|...:.||:..      |..|......:..|
  Fly   127 ------NVGRNRTVPKCGGALISERYVITAAHCTVDKPNWKLLYV------RFNEFNTSSADNCT 179

Human   340 ----EV---EKTTETSFQKEAEFGKSAKGNVRESKDL-----------------------RDIEQ 374
                ||   |.....|.....|:...   |:....|:                       .|::|
  Fly   180 TENDEVICREDYAVESIVPHPEYDMH---NISRPNDICILRLASDVTFNDYVRPICLPFDPDVQQ 241

Human   375 LQ-MDNVMAI----KVEDPKEIRKEPEDDQKYSHFPDFSYSASSKI-IISGVPSRKDHMC 428
            |. :|.:..:    :.||     :.|.|.||:...|...:.|.:.: .::.|......:|
  Fly   242 LPIVDEIFTVTGWGETED-----RRPSDTQKHVELPGLEHEACNSVYAVANVTLSDKQLC 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IQSEC1	NP_001363867.1	Sec7	618..806	CDD:460178
		IQ_SEC7_PH	838..967	CDD:465120
Sec71	NP_609675.2	PLN03076	13..1580	CDD:215560	59/320 (18%)