Protein Alignment FIG4 and fig4

DIOPT Version :10

• Sequence 1: NP_055660.1
• Gene: FIG4 / 9896
• HGNCID: 16873
• Length: 907
• Species: Homo sapiens
• Sequence 2: XP_031757753.1
• Gene: fig4 / 100379892
• XenbaseID: XB-GENE-6047255
• Length: 907
• Species: Xenopus tropicalis
• Alignment Length: 904
• Identity: 770/904 - (85%)
• Similarity: 825/904 - (91%)
• Gaps: 1/904 - (0%)

Human     5 AAPIISSVQKLVLYETRARYFLVGSNNAETKYRVLKIDRTEPKDLVIIDDRHVYTQQEVRELLGR 69
            ||||||.:|||:||||||||||||||:|||:|||||||||||||||||||:||||||||||||||
 Frog     4 AAPIISGIQKLILYETRARYFLVGSNHAETRYRVLKIDRTEPKDLVIIDDKHVYTQQEVRELLGR 68

Human    70 LDLGNRTKMGQKGSSGLFRAVSAFGVVGFVRFLEGYYIVLITKRRKMADIGGHAIYKVEDTNMIY 134
            |||||||||||||||||.|||||||:||||:||||||||||||||||||||||||||:|||:|||
 Frog    69 LDLGNRTKMGQKGSSGLSRAVSAFGIVGFVQFLEGYYIVLITKRRKMADIGGHAIYKIEDTSMIY 133

Human   135 IPNDSVRVTHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTVLRMPLEMLKSEMT-QNRQ 198
            ||||||||||||||||||||||||||||||||||||||||||||||:||||.||||||.. ..||
 Frog   134 IPNDSVRVTHPDEARYLRIFQNVDLSSNFYFSYSYDLSHSLQYNLTILRMPAEMLKSETAPHTRQ 198

Human   199 ESFDIFEDEGLITQGGSGVFGICSEPYMKYVWNGELLDIIKSTVHRDWLLYIIHGFCGQSKLLIY 263
            |.|||||||.|..||||||||||||||||||||||||..::..||||||||||||||||||||||
 Frog   199 EGFDIFEDEELSNQGGSGVFGICSEPYMKYVWNGELLQNVRDVVHRDWLLYIIHGFCGQSKLLIY 263

Human   264 GRPVYVTLIARRSSKFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFTAGSYSSYVQVRGSV 328
            ||||||||:|||||:||||||||||||||||||||||||||:.||||||||||||||||||||||
 Frog   264 GRPVYVTLMARRSSRFAGTRFLKRGANCEGDVANEVETEQIVHDASVMSFTAGSYSSYVQVRGSV 328

Human   329 PLYWSQDISTMMPKPPITLDQADPFAHVAALHFDQMFQRFGSPIIILNLVKEREKRKHERILSEE 393
            ||||||||||||||||||||||||||:.||:|||:|.||||||||||||||||||||||||||||
 Frog   329 PLYWSQDISTMMPKPPITLDQADPFAYAAAIHFDKMLQRFGSPIIILNLVKEREKRKHERILSEE 393

Human   394 LVAAVTYLNQFLPPEHTIVYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCSIL 458
            ||||||||||||||||.||||||||||||||||||||||||||||||||||||||||||.|||:|
 Frog   394 LVAAVTYLNQFLPPEHWIVYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDPYCSVL 458

Human   459 RPDEKWNELGGCVIPTGRLQTGILRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFD 523
            |||||||||||.|..:||||||:||||||||||||||||||||||||||||||||||||||||||
 Frog   459 RPDEKWNELGGVVGQSGRLQTGVLRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDKPNLQFD 523

Human   524 TDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQ 588
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   524 TDAVRLFEELYEDHGDTLSLQYGGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSNAFSDADRQ 588

Human   589 DSINLFLGVFHPTEGKPHLWELPTDFYLHHKNTMRLLPTRRSYTYWWTPEVIKHLPLPYDEVICA 653
            |:||||||||.|.|||||||||||||||||||||.|...:||||:||||:|:::||||.|||..:
 Frog   589 DAINLFLGVFRPAEGKPHLWELPTDFYLHHKNTMGLDHAKRSYTFWWTPKVLENLPLPLDEVHSS 653

Human   654 VNLKKLIVKKFHKYEEEIDIHNEFFRPYELSSFDDTFCLAMTSSARDFMPKTVGIDPSPFTVRKP 718
            .||||:.:||.::..:|.:|:||||||||||:||||||||||:||||||||:|.|||||||||||
 Frog   654 ENLKKMTIKKCNRSNDETNIYNEFFRPYELSNFDDTFCLAMTNSARDFMPKSVAIDPSPFTVRKP 718

Human   719 DETGKSVLGNKSNREEAVLQRKTAASAPPPPSEEAVSSSSEDDSGTDREEEGSVSQRSTPVKMTD 783
            |||||||.|||||:||.|||||||||||||..|||||||||||||||:|:||||||||||||.:|
 Frog   719 DETGKSVSGNKSNKEETVLQRKTAASAPPPHGEEAVSSSSEDDSGTDKEDEGSVSQRSTPVKNSD 783

Human   784 AGDSAKVTENVVQPMKELYGINLSDGLSEEDFSIYSRFVQLGQSQHKQDKNSQQPCSRCSDGVIK 848
            .||:.|.:||.:|..|:.|||||||..||.|..||:|||.||..|.||||.:....|:..:...|
 Frog   784 TGDNTKTSENYMQSTKDSYGINLSDVPSENDLQIYTRFVHLGICQQKQDKRTLHISSKPFESFAK 848

Human   849 LTPISAFSQDNIYEVQPPRVDRKSTEIFQAHIQASQGIMQPLGKEDSSMYREYIRNRYL 907
            |:.||:||.|||||||||:|||||.|||.|||||..||||||||||..||||||||||:
 Frog   849 LSCISSFSHDNIYEVQPPKVDRKSVEIFTAHIQAGHGIMQPLGKEDMLMYREYIRNRYM 907

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FIG4	NP_055660.1	Syja_N	93..423	CDD:460545	299/330 (91%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	707..788		69/80 (86%)
fig4	XP_031757753.1	COG5329	13..656	CDD:227637	581/642 (90%)
		Syja_N	92..423	CDD:460545	299/330 (91%)