Protein Alignment SEPTIN7 and pnut

DIOPT Version :9

• Sequence 1: XP_011513958.1
• Gene: SEPTIN7 / 989
• HGNCID: 1717
• Length: 460
• Species: Homo sapiens
• Sequence 2: NP_477064.1
• Gene: pnut / 35801
• FlyBaseID: FBgn0013726
• Length: 539
• Species: Drosophila melanogaster
• Alignment Length: 425
• Identity: 255/425 - (60%)
• Similarity: 317/425 - (74%)
• Gaps: 44/425 - (10%)

Human    23 QQKNLE--GYVGFANLPNQVYRKSVKRGFEFTLMVVGESGLGKSTLINSLFLTDLYSPE-YPGPS 84
            :||.:|  |||||||||||||||:|||||||||||||.|||||||||||:||:|:|:.| |||||
  Fly   113 RQKPMEIAGYVGFANLPNQVYRKAVKRGFEFTLMVVGASGLGKSTLINSMFLSDIYNAEQYPGPS 177

Human    85 HRIKKTVQVEQSKVLIKEGGVQLLLTIVDTPGFGDAVDNSNCWQPVIDYIDSKFEDYLNAESRVN 149
            .|.||||.||.:||::||.||.|.||:||||||||||||||||.|:::|:|||:|:||.|||||.
  Fly   178 LRKKKTVAVEATKVMLKENGVNLTLTVVDTPGFGDAVDNSNCWVPILEYVDSKYEEYLTAESRVY 242

Human   150 RRQMPDNRVQCCLYFIAPSGHGLKPLDIEFMKRLHEKVNIIPLIAKADTLTPEECQQFKKQIMKE 214
            |:.:.|:||.|||||||||||||.||||..|:.|.:|||::|:||||||:||:|...|||||:.|
  Fly   243 RKTISDSRVHCCLYFIAPSGHGLLPLDIACMQSLSDKVNLVPVIAKADTMTPDEVHLFKKQILNE 307

Human   215 IQEHKIKIYEFPET--DDEEENKLVKKIKDRLPLAVVGSNTIIEVNGKRVRGRQYPWGVAEVENG 277
            |.:||||||:||.|  |..||.|..:.::.|:|.||||:|||||.:||:||||:||||:.||||.
  Fly   308 IAQHKIKIYDFPATLEDAAEEAKTTQNLRSRVPFAVVGANTIIEQDGKKVRGRRYPWGLVEVENL 372

Human   278 EHCDFTILRNMLIRTHMQDLKDVTNNVHYENYRSRKLAAVTYNGVDNNKNKGQLTKHLMITLNIR 342
            .||||..||||:||||:||||||||||||||||.|||:.:   |:.:.|.:            :.
  Fly   373 THCDFIALRNMVIRTHLQDLKDVTNNVHYENYRCRKLSEL---GLVDGKAR------------LS 422

Human   343 DRSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVKEKVQKLKDSEAEVQRTFLASEKG------- 400
            :::||.|||||:|||..||||||.||||||:||||||:|||:|||.|:.|.....:|.
  Fly   423 NKNPLTQMEEEKREHEQKMKKMEAEMEQVFDMKVKEKMQKLRDSELELARRHEERKKALELQIRE 487

Human   401 LQKKRHRVMDSQSHKKVISPLLLVCWDLPHQWQQV 435
            |::||.   :.:..||              :|:.|
  Fly   488 LEEKRR---EFEREKK--------------EWEDV 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SEPTIN7	XP_011513958.1	CDC3	29..419	CDD:227352	250/399 (63%)
		CDC_Septin	47..317	CDD:206649	189/272 (69%)
pnut	NP_477064.1	CDC3	121..482	CDD:227352	245/375 (65%)
		Septin	139..411	CDD:279124	189/271 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	394	1.000	Domainoid score	I764
eggNOG	1	0.900	-	-		E1_COG5019
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1354
Inparanoid	1	1.050	543	1.000	Inparanoid score	I1177
Isobase	1	0.950	-	0	Normalized mean entropy	S765
OMA	1	1.010	-	-		QHG51878
OrthoDB	1	1.010	-	-		D452703at33208
OrthoFinder	1	1.000	-	-		FOG0000103
OrthoInspector	1	1.000	-	-		oto89010
orthoMCL	1	0.900	-	-		OOG6_104146
Panther	1	1.100	-	-	LDO	PTHR18884
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2060
SonicParanoid	1	1.000	-	-		X204
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.820