DRSC/TRiP Functional Genomics Resources

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Protein Alignment ZBTB24 and CG12605

DIOPT Version :9

Sequence 1:NP_055612.2 Gene:ZBTB24 / 9841 HGNCID:21143 Length:697 Species:Homo sapiens
Sequence 2:NP_001261387.1 Gene:CG12605 / 38468 FlyBaseID:FBgn0035481 Length:619 Species:Drosophila melanogaster


Alignment Length:514 Identity:115/514 - (22%)
Similarity:187/514 - (36%) Gaps:122/514 - (23%)


- Green bases have known domain annotations that are detailed below.


Human   103 EKSTEQILATAQFLKVYDLVKAYTDFQNNHSSPKPTTLNTAGAPVVV-------ISNKK------ 154
            |:..:|:....::.....||:     .|:....|.....|.|:|..|       :|.::      
  Fly   115 EEQEDQLCEHLEWSAAQSLVQ-----MNSSKQEKQRRAGTTGSPATVAAPVSASVSLRRPVGRAP 174

Human   155 -ND-------PPKRKRGRPKKVN--TLQEEKSELAAEEEIQLRVNNSVQNRQNFVVKGDSGVLNE 209
             .|       ||....|.|::..  .|:.|:......|..:.|..:.::.:|.......:.:.. 
  Fly   175 AEDGKVIFYAPPASASGSPRQPEPVALKRERERDKEREREKERERDRMREQQLVAATAAASIYR- 238

Human   210 QIAAKEKEESE-------------PTCEPSREEEMPVEKDENYDPKTEDGQASQSRYSKRRIWRS 261
               .:..||:|             |...|.....|..|:::...|:.::...|.|..|.:...|.
  Fly   239 ---GRSVEETEAAHDLLSLSQSLPPLIPPCVVTIMKQEQEQLRSPEIQEISNSASSRSPQSTIRF 300

Human   262 VKLKDYKLVGDQEDHGSAKRICGRRKRPGGPEARCKDCGKVFKYNHFLAIHQRSHTGERPFKCNE 326
            :....|.|:|...:..:.   |.....|....:...|          :.:...|.:|     ..:
  Fly   301 IGSSSYDLMGGSSEGANN---CSPLTPPNSDHSSDVD----------IDMSSSSESG-----LQQ 347

Human   327 CGKGFAQKH-----SLQVHTRMHTGERPYTCTVCSK-ALTTKH---------------------- 363
            .||...|::     :|::...|..|.     |..|| |..||.                      
  Fly   348 WGKPNPQQNQQRASALKMCLNMLDGR-----TKASKAAAVTKQDRQEPMQPRPKSAQSNASSGGG 407

Human   364 ----------SLLEHMSLHSGQK-------SFTCDQCGKYFSQNRQLKSHYRVH---TGHSLPEC 408
                      :.|.|.|..:|:.       .:.|.:|||.::.:..|..|.:.|   ...|..:|
  Fly   408 PPSEPPENPAASLGHSSSGNGENYAKRKRGCYKCCECGKQYATSSNLSRHKQTHRSLDSQSAKKC 472

Human   409 KDCHRKFMDVSQLKKHLRTHTGEKPFTCEICGKSFTAKSSLQTHIRIHRGEKPYSCGICGKSFSD 473
            ..|.:.::.:..|..||.||  :...:|:||||.|:....||.|:|.|.|||||:|..|||:|:|
  Fly   473 NTCGKAYVSMPALAMHLLTH--KLSHSCDICGKLFSRPWLLQGHLRSHTGEKPYACVHCGKAFAD 535

Human   474 SSAKRRHCILHTGKKPFSCPECNLQFARLDNLKAHLKIHSKEKHASDASSISGSSNTEE 532
            .|..|.|...|:|.|.|.|..||..||    ||::|..|.:.....||.:|......||
  Fly   536 RSNLRAHMQTHSGDKNFKCHRCNKTFA----LKSYLNKHLESACLRDAGAIDQGKGLEE 590

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZBTB24NP_055612.2 BTB 27..133 CDD:306997 5/29 (17%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 131..176 13/67 (19%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 209..254 10/57 (18%)
C2H2 Zn finger 296..316 CDD:275368 1/19 (5%)
COG5048 <321..480 CDD:227381 55/206 (27%)
C2H2 Zn finger 324..344 CDD:275368 4/24 (17%)
C2H2 Zn finger 352..372 CDD:275368 9/52 (17%)
C2H2 Zn finger 380..400 CDD:275368 6/19 (32%)
C2H2 Zn finger 408..428 CDD:275368 5/19 (26%)
C2H2 Zn finger 436..456 CDD:275368 10/19 (53%)
C2H2 Zn finger 464..480 CDD:275368 8/15 (53%)
C2H2 Zn finger 492..512 CDD:275368 8/19 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 652..697
CG12605NP_001261387.1 zf-C2H2 439..461 CDD:278523 6/21 (29%)
C2H2 Zn finger 441..461 CDD:275370 6/19 (32%)
C2H2 Zn finger 472..492 CDD:275368 5/19 (26%)
COG5048 492..>570 CDD:227381 38/83 (46%)
zf-C2H2 496..518 CDD:278523 10/21 (48%)
C2H2 Zn finger 498..518 CDD:275368 10/19 (53%)
zf-H2C2_2 511..534 CDD:290200 14/22 (64%)
zf-C2H2 524..546 CDD:278523 10/21 (48%)
C2H2 Zn finger 526..546 CDD:275368 9/19 (47%)
zf-H2C2_2 538..562 CDD:290200 9/23 (39%)
C2H2 Zn finger 554..571 CDD:275368 8/20 (40%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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