Protein Alignment SCRN1 and CG10098

DIOPT Version :10

• Sequence 1: NP_001138986.1
• Gene: SCRN1 / 9805
• HGNCID: 22192
• Length: 434
• Species: Homo sapiens
• Sequence 2: NP_649694.1
• Gene: CG10098 / 40851
• FlyBaseID: FBgn0037472
• Length: 353
• Species: Drosophila melanogaster
• Alignment Length: 422
• Identity: 110/422 - (26%)
• Similarity: 182/422 - (43%)
• Gaps: 90/422 - (21%)

Human    29 CFVAFPPRAKDGLVVFGKNSARPRDE-----VQEVVYFSAADHEPESKVECTYISIDQVPRTYAI 88
            |||..|....:|.::.|:|:   .||     ..||.::.|.: ..|.|.: ...|.:.......:
  Fly     6 CFVVLPENCAEGTLIIGRNA---EDEKNVNVASEVCFYDATE-VLEGKTD-GGASAETGGDMLRV 65

Human    89 MISRP-AWLWGAEMGANEHGVCIANEAINTREPAAEIEALLGMDLVRLGLERGETAKEALDVIVS 152
            ::.:| ..|||.:.||||.||.:..........|.:.::|||.|:|||.|...:...:|:|.|.:
  Fly    66 ILQKPQPGLWGGDFGANERGVALGLTWAAGENEAKDSDSLLGTDIVRLTLAVAKDVDDAVDRIGA 130

Human   153 LLEEHGQGGNYFEDANSCHSFQSAYLIVDRDEAWVLETIGKYWAAEKVTEG-VRCICSQLSLTTK 216
            |:..||...:...           ::..|...||::...||.|||||:... :|.....|::||.
  Fly   131 LVASHGHDNSKLN-----------FIACDAAAAWLVSCSGKVWAAEKLEASFLRLPSGGLAVTTV 184

Human   217 MDAEHPEL---RSYAQSQGWWTGEGEFNFSEVFSPVEDHLDCG---AGKDSLEKQEESITVQTMM 275
            ::.....|   .|:|.:..          :|..:|..|.  ||   ||..:..:.:...|:::..
  Fly   185 VNKSSEGLDDAASFAAAHD----------AEAQAPAVDW--CGPKPAGDGTYTQHDMFETLRSAS 237

Human   276 NTLRDKASGVCIDSEFFLTTASGVSVLPQNRSSPCIHYFTGTPDPSRSIFKPFIFVDDVKLVPKT 340
            |....:|:.|.:      .:..|:|         | |:|||||:.:.|:||||:|..:.::.|.|
  Fly   238 NASSSRAATVSV------LSVKGIS---------C-HWFTGTPNAAESVFKPFVFAPNPRISPLT 286

Human   341 QSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWAR-AIIESDQEQGRKLRSTMLELEKQGLEAME 404
            |               .|.:.|.. .|:|.|...: |.:|       .|||    ||   |..::
  Fly   287 Q---------------VQAEADLT-LLHKLHSQRKPAALE-------HLRS----LE---LSCVD 321

Human   405 EILTSSEPLDPA--EVGDLFYDCVDTEIKFFK 434
            |:.......|.|  |:.:|..|||:.|:||::
  Fly   322 ELNNYFSLQDHASDELDELLKDCVEAEVKFYR 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCRN1	NP_001138986.1	PepD	38..>251	CDD:477862	55/222 (25%)
CG10098	NP_649694.1	PepD	70..>167	CDD:477862	34/107 (32%)