Protein Alignment RIMS3 and Fife

DIOPT Version :10

• Sequence 1: NP_055562.2
• Gene: RIMS3 / 9783
• HGNCID: 21292
• Length: 308
• Species: Homo sapiens
• Sequence 2: NP_001261340.1
• Gene: Fife / 38337
• FlyBaseID: FBgn0264606
• Length: 1314
• Species: Drosophila melanogaster
• Alignment Length: 300
• Identity: 80/300 - (26%)
• Similarity: 130/300 - (43%)
• Gaps: 57/300 - (19%)

Human    11 SGASRNVVRSSSISGEI---------------CGSQQAGGGAGTTTAKKRRSSLGAKMVAIVGLT 60
            :.::.||.:.:...|::               .|..||.....|||..:|:   |:..||.|..|
  Fly  1041 AASASNVAQDTQRQGQLLTTNPLQQRKSSMFQLGESQASPPTTTTTHLQRK---GSMYVAKVTET 1102

Human    61 QWSKSTLQLPQPEGATKKLRSNIRRSTETGIAVEMRSRVTRQGSRESTDGSTNSNSSDGTFIFPT 125
                      .|.|...:..|..:||. .|::|:.....:.|  |:.:...|.|.|.  ..|.|.
  Fly  1103 ----------PPHGTPTRKGSVYQRSV-VGLSVDSPGADSPQ--RKQSVVKTLSGSY--VNICPL 1152

Human   126 TRLGAESQFSDFLDG--LGPAQIVGR-QTLATPPMGDVHIAIMDRSGQLEVEVIEARGL------ 181
            |  |.||.:     |  |||:||..: ..|.|...|::.:..:...|.:|||:|.||.:
  Fly  1153 T--GGESSY-----GLKLGPSQIHPKGYRLTTARYGELKMGFLKIKGNVEVELICARNIVNEDCE 1210

Human   182 TPKPGSKSLPATYIKVYLLENGACLAKKKTKMTKKTCDPLYQQALLFDEGPQ-GKVLQVIVWGDY 245
            ||       |.||:|.|:.:......||||::.:...:|||:|.:.:..... |:.:.::||...
  Fly  1211 TP-------PDTYVKCYIKDGDRLRHKKKTRVVRHAAEPLYRQTIKYQSSDVFGRNIVIMVWQRC 1268

Human   246 GRMDHKCFMGMAQIMLDELDLSAAVTGWYKLFPTSSVADS 285
            ...:|...:|..::.||:|.:...::|||.|||..|...|
  Fly  1269 VGFEHNQGLGGTEVNLDKLSIGQPISGWYPLFPMHSYGGS 1308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RIMS3	NP_055562.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..120		8/33 (24%)
		C2	141..286	CDD:472691	45/152 (30%)
Fife	NP_001261340.1	FYVE_BSN_PCLO	130..187	CDD:277290
		PDZ_RIM-like	487..580	CDD:467198
		C2A_RIM1alpha	651..779	CDD:175997
		C2	1163..1304	CDD:472691	44/147 (30%)