Protein Alignment EIF4A3 and CG7483

DIOPT Version :9

• Sequence 1: NP_055555.1
• Gene: EIF4A3 / 9775
• HGNCID: 18683
• Length: 411
• Species: Homo sapiens
• Sequence 2: NP_649788.2
• Gene: CG7483 / 40987
• FlyBaseID: FBgn0037573
• Length: 399
• Species: Drosophila melanogaster
• Alignment Length: 399
• Identity: 350/399 - (87%)
• Similarity: 377/399 - (94%)
• Gaps: 1/399 - (0%)

Human    13 ARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRD 77
            |||. .:.||::.|||||||:|:|.|||:.|.|:|:|||||||||||||||||||:|..|:||||
  Fly     2 ARKN-AQAEDLSNVEFETSEDVEVIPTFNAMNLKEELLRGIYAYGFEKPSAIQQRSITPIVKGRD 65

Human    78 VIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIG 142
            ||||:|||||||||||||:||.||..:||||.|.|:|||||||||||.:|||||.||||||.|||
  Fly    66 VIAQAQSGTGKTATFSISILQSLDTTLRETQVLCLSPTRELAVQIQKVILALGDMMNVQCHVCIG 130

Human   143 GTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRY 207
            |||:||||||||||||:|:||||||||||:||.||||||||||||||||||||||||||||||||
  Fly   131 GTNLGEDIRKLDYGQHIVSGTPGRVFDMIKRRVLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRY 195

Human   208 LPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLY 272
            ||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||||||||
  Fly   196 LPPATQVVLISATLPHEILEMTSKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLY 260

Human   273 DTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVW 337
            ||||||||||||||||||||||||||||||||||||||||||||:.||||||:|.|||||:||||
  Fly   261 DTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERDEIMKEFRAGQSRVLITTDVW 325

Human   338 ARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDE 402
            |||:||.||||:|||||||||||||||||||||:|||||||||||:|||||||||||||||||||
  Fly   326 ARGIDVQQVSLVINYDLPNNRELYIHRIGRSGRFGRKGVAINFVKSDDIRILRDIEQYYSTQIDE 390

Human   403 MPMNVADLI 411
            |||||||||
  Fly   391 MPMNVADLI 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EIF4A3	NP_055555.1	PTZ00424	35..411	CDD:185609	335/375 (89%)
		Q motif	38..66		22/27 (81%)
		DEAD box. /evidence=ECO:0000305	187..190		2/2 (100%)
CG7483	NP_649788.2	PTZ00424	4..399	CDD:185609	346/395 (88%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147323
Domainoid	1	1.000	283	1.000	Domainoid score	I1654
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5602
Inparanoid	1	1.050	703	1.000	Inparanoid score	I672
Isobase	1	0.950	-	0	Normalized mean entropy	S104
OMA	1	1.010	-	-		QHG53631
OrthoDB	1	1.010	-	-		D321438at33208
OrthoFinder	1	1.000	-	-		FOG0000304
OrthoInspector	1	1.000	-	-		oto91293
orthoMCL	1	0.900	-	-		OOG6_101114
Panther	1	1.100	-	-	LDO	PTHR47958
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R429
SonicParanoid	1	1.000	-	-		X250
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	15	14.890