Protein Alignment SLK and lic

DIOPT Version :10

• Sequence 1: NP_055535.2
• Gene: SLK / 9748
• HGNCID: 11088
• Length: 1235
• Species: Homo sapiens
• Sequence 2: NP_477162.1
• Gene: lic / 32257
• FlyBaseID: FBgn0261524
• Length: 334
• Species: Drosophila melanogaster
• Alignment Length: 290
• Identity: 99/290 - (34%)
• Similarity: 148/290 - (51%)
• Gaps: 27/290 - (9%)

Human    32 DFWEIIGELGDGAFGKVYKAQNKET-SVLAAAKVIDTKSEEELEDYMVEIDI-LASCDHPNIVKL 94
            |..|.|.:||.||:|.|.|.::|:| :|||..::..|.:..|....::::|| :.|.|.|..|..
  Fly    44 DSLEKICDLGRGAYGIVDKMRHKQTDTVLAVKRIPMTVNIREQHRLVMDLDISMRSSDCPYTVHF 108

Human    95 LDAFYYENNLWILIEFCAGGAVDAVMLELERP--------LTESQIQVVCKQTLDALNYLHDN-K 150
            ..|.|.|.::||.:|      |.:..|:...|        :.||.:..:....:.||:|||.. |
  Fly   109 YGAMYREGDVWICME------VMSTSLDKFYPKVFLHDLRMEESVLGKIAMSVVSALHYLHAQLK 167

Human   151 IIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVVMCETSKDRP--YD 213
            :||||:|..|||....|.:|:.|||:|.....:|.:.......|| ||||.:   ..:..|  ||
  Fly   168 VIHRDVKPSNILINRAGQVKICDFGISGYLVDSIAKTIDAGCKPY-MAPERI---DPQGNPAQYD 228

Human   214 YKADVWSLGITLIEMAEIEPPHHE-LNPMRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNV 277
            .::|||||||.:||||....|:.. ..|...|.::.:..||.|.: ..:|..|:||:..||:|..
  Fly   229 IRSDVWSLGIGMIEMATGRYPYDNWRTPFEQLRQVVEDSPPRLPE-GTFSPEFEDFIAVCLQKEY 292

Human   278 DARWTTSQLLQHPFVT--VDSNKPIRELIA 305
            .||....|||:|.|:.  :..|..|.|.:|
  Fly   293 MARPNYEQLLKHSFIVEHLQRNTDISEFVA 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLK	NP_055535.2	STKc_SLK	28..309	CDD:270811	99/290 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	309..351
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	363..393
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	421..441
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	519..539
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	613..760
		PKK	852..990	CDD:463600
		PKK	1020..1160	CDD:463600
lic	NP_477162.1	PKc_MKK3_6	44..326	CDD:173729	99/290 (34%)