Protein Alignment SLK and tea5

DIOPT Version :10

• Sequence 1: NP_055535.2
• Gene: SLK / 9748
• HGNCID: 11088
• Length: 1235
• Species: Homo sapiens
• Sequence 2: NP_594646.1
• Gene: tea5 / 2543100
• PomBaseID: SPAC12B10.14C
• Length: 665
• Species: Schizosaccharomyces pombe
• Alignment Length: 249
• Identity: 55/249 - (22%)
• Similarity: 102/249 - (40%)
• Gaps: 33/249 - (13%)

Human    53 NKETSVLAAAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVD 117
            :||..|:   |..|..:.......:.|:..|:...|.|:::..::|:|.||:|.:.|:    ...
pombe   410 DKEVVVI---KRFDISAVTHRRLLLEELQRLSGLSHKNLIRYNESFWYLNNIWSVFEY----KDP 467

Human   118 AVMLELERP---LTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAK 179
            :..|....|   .:|..|..:|.:....|.:||::.|.|.:|....|..|....:|:.::..|:.
pombe   468 STKLSALIPKYFFSELNIASICYEISSGLAFLHNSGIAHHNLTTECIYLTKSSCLKIGNYAFSSP 532

Human   180 NTRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVL 244
            .......|.:....|.|:        ..|:....:..||.|||:..:|:.:.:|     |..|..
pombe   533 YIERQTNRGAVSHVPDWL--------IEKNYKEGFMKDVKSLGLVALEIFQGQP-----NFFRKS 584

Human   245 LKIAKSEPPTLAQPSR----WSSNFKDFLKKCLE------KNVDARWTTSQLLQ 288
            ::..:..|......:|    .|..||:||.:.|:      .|::....||..|:
pombe   585 IQSIQLTPNANVLVNRVRGLISQEFKEFLLQTLQAETLQGPNINMLLETSSFLE 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLK	NP_055535.2	STKc_SLK	28..309	CDD:270811	55/249 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	309..351
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	363..393
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	421..441
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	519..539
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	613..760
		PKK	852..990	CDD:463600
		PKK	1020..1160	CDD:463600
tea5	NP_594646.1	Protein Kinases, catalytic domain	387..638	CDD:473864	54/247 (22%)