Protein Alignment PRORP and Prorp

DIOPT Version :10

• Sequence 1: NP_055487.2
• Gene: PRORP / 9692
• HGNCID: 19958
• Length: 583
• Species: Homo sapiens
• Sequence 2: NP_079649.1
• Gene: Prorp / 66132
• MGIID: 1913382
• Length: 584
• Species: Mus musculus
• Alignment Length: 587
• Identity: 453/587 - (77%)
• Similarity: 507/587 - (86%)
• Gaps: 11/587 - (1%)

Human     1 MTFYLFGIRSFPKLWKS-PYLGLGPGHSYVSLFLADRCGIRNQQRLFSLKTMSPQNTKATNLI-A 63
            |||||.|.||.|||||| ||..|||..|....||   |.|.||||.||:|..:|.|:||.||: .
Mouse     1 MTFYLSGFRSIPKLWKSNPYFELGPATSSTPFFL---CAIGNQQRWFSVKPTTPPNSKALNLLDT 62

Human    64 KARYLRKDEGSNKQVYSVPHFFLAGAAKERSQM--NSQTEDHALAPVRNTIQLPTQPLNSEEWDK 126
            |||..||...:|.||.|.||:|.|||||:||.:  |.|.:.||| |||:::||||:||||.||||
Mouse    63 KARTHRKGNDNNGQVSSDPHYFAAGAAKKRSHIGANPQNQGHAL-PVRSSVQLPTKPLNSAEWDK 126

Human   127 LKEDLKENTGKTSFESWIISQMAGCHSSIDVAKSLLAWVAAKNNGIVSYDLLVKYLYLCVFHMQT 191
            ||||.|   ||.|||.:||||||....|:||||||||||||||||||.|:||||||||||||.||
Mouse   127 LKEDFK---GKASFEDFIISQMARNCCSVDVAKSLLAWVAAKNNGIVGYNLLVKYLYLCVFHKQT 188

Human   192 SEVIDVFEIMKARYKTLEPRGYSLLIRGLIHSDRWREALLLLEDIKKVITPSKKNYNDCIQGALL 256
            ||||||:|||||:||:||..||:||||||||||||||:||||||||||:.||||||.||||||||
Mouse   189 SEVIDVYEIMKAKYKSLESGGYTLLIRGLIHSDRWRESLLLLEDIKKVMVPSKKNYGDCIQGALL 253

Human   257 HQDVNTAWNLYQELLGHDIVPMLETLKAFFDFGKDIKDDNYSNKLLDILSYLRNNQLYPGESFAH 321
            ||||||||||||||:||:::|.|||||||||:||||.||:||:||||||.|||||||||||||||
Mouse   254 HQDVNTAWNLYQELIGHNLIPPLETLKAFFDYGKDINDDHYSDKLLDILLYLRNNQLYPGESFAH 318

Human   322 SIKTWFESVPGKQWKGQFTTVRKSGQCSGCGKTIESIQLSPEEYECLKGKIMRDVIDGGDQYRKT 386
            ||||||||:||:||||||||::|||||||||:|||.|.|||||||.||.|||||||||||||:||
Mouse   319 SIKTWFESIPGRQWKGQFTTIQKSGQCSGCGRTIEPIHLSPEEYEFLKEKIMRDVIDGGDQYKKT 383

Human   387 TPQELKRFENFIKSRPPFDVVIDGLNVAKMFPKVRESQLLLNVVSQLAKRNLRLLVLGRKHMLRR 451
            |||||||||:|:.|.||||:|||||||||||||.||||.||.||||||::||:|||||||||||.
Mouse   384 TPQELKRFESFVNSCPPFDIVIDGLNVAKMFPKGRESQNLLGVVSQLAQQNLQLLVLGRKHMLRP 448

Human   452 SSQWSRDEMEEVQKQASCFFADDISEDDPFLLYATLHSGNHCRFITRDLMRDHKACLPDAKTQRL 516
            ||||.::|||:|:|||.|||||:|||||||||||||:|||||:|||:||:||||||||||:||||
Mouse   449 SSQWRKEEMEQVRKQAHCFFADNISEDDPFLLYATLNSGNHCKFITKDLLRDHKACLPDARTQRL 513

Human   517 FFKWQQGHQLAIVNRFPGSKLTFQRILSYDTVVQTTGDSWHIPYDEDLVERCSCEVPTKWLCLHQ 581
            ||||||||||||:..|..||||||.|||||||||.||||||||||||||:|.|||||||||||.:
Mouse   514 FFKWQQGHQLAIMKGFQKSKLTFQHILSYDTVVQRTGDSWHIPYDEDLVQRSSCEVPTKWLCLQR 578

Human   582 KT 583
            ||
Mouse   579 KT 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRORP	NP_055487.2	PPR repeat	174..204	CDD:276811	25/29 (86%)
		PPR repeat	210..239	CDD:276811	24/28 (86%)
		PPR repeat	244..271	CDD:276811	25/26 (96%)
		PRORP	342..578	CDD:465320	194/235 (83%)
Prorp	NP_079649.1	PPR repeat	170..201	CDD:276811	26/30 (87%)
		PPR repeat	207..235	CDD:276811	23/27 (85%)
		PRORP	339..575	CDD:465320	194/235 (83%)