Protein Alignment PRORP and prorp

DIOPT Version :10

• Sequence 1: NP_055487.2
• Gene: PRORP / 9692
• HGNCID: 19958
• Length: 583
• Species: Homo sapiens
• Sequence 2: XP_683289.3
• Gene: prorp / 555630
• ZFINID: ZDB-GENE-100618-4
• Length: 578
• Species: Danio rerio
• Alignment Length: 554
• Identity: 254/554 - (45%)
• Similarity: 366/554 - (66%)
• Gaps: 37/554 - (6%)

Human    53 PQN-TKATNLIAK--ARYL-----RKDEGSNKQVY------SVPH-FFLAGAAKERSQ------- 95
            |.| |.|..||..  .||.     ::.:..|::.:      :.|| .|.||||::|::
Zfish    32 PHNITNAVRLIINPHTRYYTTKRDKQAQSPNEKGFTPRTRPAFPHSVFSAGAARKRAEFLKHKSG 96

Human    96 MNSQTEDHALAPVR-----NTIQLPTQPLNSEEWDKLKEDLKENTGKTSFESWIISQMAGCHSSI 155
            ::::.:|   .|||     |.: ||.:||...||..||:|...   ...||..::..:...:..:
Zfish    97 LDTENDD---TPVRVRDSPNMV-LPDRPLTPSEWTNLKKDFSR---PELFEKVMMENLVRANVDV 154

Human   156 DVAKSLLAWVAAKNNGIVSYDLLVKYLYLCVFHMQTSEVIDVFEIMKARYKTLEPRGYSLLIRGL 220
            ::|||||::| .::.|.:||::|::||.:||.....|||.|.::||::.:|:|:....:|.|:|.
Zfish   155 NIAKSLLSYV-VQDKGTLSYEILLRYLTICVRAGHHSEVFDAYDIMRSCFKSLDLGASALFIKGF 218

Human   221 IHSDRWREALLLLEDIKKVITPSKKNYNDCIQGALLHQDVNTAWNLYQELLGHDIVPMLETLKAF 285
            ..:|||:||:.:|:|:||.:.||.:||.|.|.||:||.|..|:|.||.|||...:||..:|.:..
Zfish   219 SQTDRWKEAISMLQDMKKALLPSPRNYGDVIAGAVLHGDSETSWKLYDELLELGLVPGQDTWQCL 283

Human   286 FDFGKDIKDDNYSNKLLDILSYLRNNQLYPGESFAHSIKTWFESVPGKQWKGQFTTVRKSGQCSG 350
            |..|  |....:.:||.|:|||:|:||:||.:....:||.||||:|.::|:|:|::|..||.|..
Zfish   284 FQSG--ITQRGHEDKLFDVLSYMRDNQIYPEKPLMETIKAWFESLPDQKWRGKFSSVTPSGDCRN 346

Human   351 CGKTIESIQLSPEEYECLKGKIMRDVIDGGDQYRKTTPQELKRFENFIKSRPPFDVVIDGLNVAK 415
            |...:|||||:..||..||..:|..||:|||.:.|:.|:|||.|::|:|.|||||:|||||||||
Zfish   347 CKALLESIQLTEVEYAQLKHNVMEKVIEGGDVFNKSNPEELKSFKSFVKQRPPFDIVIDGLNVAK 411

Human   416 MFPKVRESQLLLNVVSQLAKRNLRLLVLGRKHMLRRSSQWSRDEMEEVQKQASCFFADDISEDDP 480
            |.|...:|:.||.|||:|.:::|.:||||||||||.|..|.|..|..::::|.|||.:|||||||
Zfish   412 MLPHAAQSETLLAVVSELEQQSLNILVLGRKHMLRHSRNWDRQNMSLIKQKAHCFFTEDISEDDP 476

Human   481 FLLYATLHSGNHCRFITRDLMRDHKACLPDAKTQRLFFKWQQGHQLAIVNRFPGSKLTFQRILSY 545
            :||||.|:||.||:|::|||||||||||||:.|:.||||||:||||.|.:..||.::.|:|||||
Zfish   477 YLLYAALNSGVHCKFLSRDLMRDHKACLPDSATRCLFFKWQRGHQLVISHYTPGKRVRFERILSY 541

Human   546 DTVVQTTGDSWHIPYDEDLVERCSCEVPTKWLCL 579
            ||::||.|.|||||||:...:|.|.|||.|||||
Zfish   542 DTIIQTNGSSWHIPYDQKAEDRASYEVPQKWLCL 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRORP	NP_055487.2	PPR repeat	174..204	CDD:276811	13/29 (45%)
		PPR repeat	210..239	CDD:276811	11/28 (39%)
		PPR repeat	244..271	CDD:276811	14/26 (54%)
		PRORP	342..578	CDD:465320	139/235 (59%)
prorp	XP_683289.3	PPR repeat	172..202	CDD:276811	13/29 (45%)
		PPR repeat	215..237	CDD:276811	10/21 (48%)
		PPR repeat	242..271	CDD:276811	16/28 (57%)
		PPR repeat	277..307	CDD:276811	11/31 (35%)
		PRORP	338..574	CDD:465320	139/235 (59%)