Protein Alignment PRORP and Prorp

DIOPT Version :10

• Sequence 1: NP_055487.2
• Gene: PRORP / 9692
• HGNCID: 19958
• Length: 583
• Species: Homo sapiens
• Sequence 2: NP_001100200.1
• Gene: Prorp / 299050
• RGDID: 1305089
• Length: 587
• Species: Rattus norvegicus
• Alignment Length: 587
• Identity: 447/587 - (76%)
• Similarity: 501/587 - (85%)
• Gaps: 8/587 - (1%)

Human     1 MTFYLFGIRSFPKLWKS-PYLGLGPGHSYVSLFLADRCGIRNQQRLFSLKTMSPQNTKATN-LIA 63
            |||||.|.|||.||||| ||..|||..|..|.||...|.|.||||.||:|..:|.|:|..| |:.
  Rat     1 MTFYLSGFRSFLKLWKSNPYFELGPATSSASFFLGVHCVIGNQQRWFSVKPTTPPNSKILNLLVT 65

Human    64 KARYLRKDEGSNKQVYSVPHFFLAGAAKERSQM--NSQTEDHALAPVRNTIQLPTQPLNSEEWDK 126
            |||.|:|...||||..|.||:|.||.||:||.:  |.|.:.|.| ||::|:||||:|||||||||
  Rat    66 KARTLKKGNDSNKQASSGPHYFAAGEAKKRSHLSGNPQNQGHTL-PVKSTVQLPTKPLNSEEWDK 129

Human   127 LKEDLKENTGKTSFESWIISQMAGCHSSIDVAKSLLAWVAAKNNGIVSYDLLVKYLYLCVFHMQT 191
            ||||.|   ||.|||.::||||....||:||||||||||||||||||.|:||||||||||||.||
  Rat   130 LKEDFK---GKASFEDFVISQMTRSCSSVDVAKSLLAWVAAKNNGIVGYNLLVKYLYLCVFHKQT 191

Human   192 SEVIDVFEIMKARYKTLEPRGYSLLIRGLIHSDRWREALLLLEDIKKVITPSKKNYNDCIQGALL 256
            ||||||:|||||:||:||..||:|||||||||||||||||||||||||:.||||||.||||||||
  Rat   192 SEVIDVYEIMKAKYKSLESGGYTLLIRGLIHSDRWREALLLLEDIKKVMVPSKKNYGDCIQGALL 256

Human   257 HQDVNTAWNLYQELLGHDIVPMLETLKAFFDFGKDIKDDNYSNKLLDILSYLRNNQLYPGESFAH 321
            |||||.||:|||||:||:::|:|||||||||.|||:.||.|||:|||||.|||||||||||||||
  Rat   257 HQDVNVAWSLYQELVGHNLIPLLETLKAFFDHGKDMNDDQYSNQLLDILLYLRNNQLYPGESFAH 321

Human   322 SIKTWFESVPGKQWKGQFTTVRKSGQCSGCGKTIESIQLSPEEYECLKGKIMRDVIDGGDQYRKT 386
            ||||||||:||:||||||||::||||||.||:.||||.|||||||.||..||||||||||||:||
  Rat   322 SIKTWFESIPGRQWKGQFTTIQKSGQCSSCGRAIESIHLSPEEYEFLKETIMRDVIDGGDQYKKT 386

Human   387 TPQELKRFENFIKSRPPFDVVIDGLNVAKMFPKVRESQLLLNVVSQLAKRNLRLLVLGRKHMLRR 451
            |||||||||.|:||.||||:|||||||||||||.||||.||.:|||||::||:|||||||||||.
  Rat   387 TPQELKRFERFVKSCPPFDIVIDGLNVAKMFPKGRESQNLLGIVSQLAQQNLQLLVLGRKHMLRP 451

Human   452 SSQWSRDEMEEVQKQASCFFADDISEDDPFLLYATLHSGNHCRFITRDLMRDHKACLPDAKTQRL 516
            ||||.:||||:|:|||.|||||:|||||||||||||:||:||:|||:||:||||||||||:.|||
  Rat   452 SSQWRKDEMEQVRKQAHCFFADNISEDDPFLLYATLNSGSHCKFITKDLLRDHKACLPDARAQRL 516

Human   517 FFKWQQGHQLAIVNRFPGSKLTFQRILSYDTVVQTTGDSWHIPYDEDLVERCSCEVPTKWLCLHQ 581
            ||||||||||||...|..||||||.|||||||||||||:||||||||||.|.|||||||||||.:
  Rat   517 FFKWQQGHQLAITKGFLKSKLTFQHILSYDTVVQTTGDTWHIPYDEDLVPRSSCEVPTKWLCLQR 581

Human   582 KT 583
            ||
  Rat   582 KT 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRORP	NP_055487.2	PPR repeat	174..204	CDD:276811	25/29 (86%)
		PPR repeat	210..239	CDD:276811	25/28 (89%)
		PPR repeat	244..271	CDD:276811	23/26 (88%)
		PRORP	342..578	CDD:465320	191/235 (81%)
Prorp	NP_001100200.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	94..114		8/20 (40%)
		PPR repeat	174..204	CDD:276811	25/29 (86%)
		PPR repeat	210..239	CDD:276811	25/28 (89%)
		PPR repeat	244..271	CDD:276811	23/26 (88%)
		PRORP	342..578	CDD:465320	191/235 (81%)