Protein Alignment PRORP and prorp

DIOPT Version :10

• Sequence 1: NP_055487.2
• Gene: PRORP / 9692
• HGNCID: 19958
• Length: 583
• Species: Homo sapiens
• Sequence 2: XP_002935379.1
• Gene: prorp / 100125795
• XenbaseID: XB-GENE-1020924
• Length: 583
• Species: Xenopus tropicalis
• Alignment Length: 600
• Identity: 271/600 - (45%)
• Similarity: 383/600 - (63%)
• Gaps: 44/600 - (7%)

Human     3 FYL-FGIRSFPK---LWKS-PYLGLGPGHSYV--SLFLADRC-GIR---NQQRLFSLKTMSPQNT 56
            ||| ..|:|:.:   :|.. |.|....|...:  ::....:| |:|   |.:..|:.::...:|.
 Frog     7 FYLTLCIKSYGRNVLMWHGVPPLNCHEGRERLLKNIRTISKCLGVRAGDNNKNSFARQSKPSKNK 71

Human    57 KATNLIAKARYLRKDEGSNKQVYSVPH---FFLAGAAKERSQ-----MNSQTEDHALAPVRNTIQ 113
            ...|            ||       ||   .|.|||||.||:     ..:..:...::..:..:|
 Frog    72 FDRN------------GS-------PHSITVFSAGAAKARSEGMQHKAKASPDSDNISSQKERVQ 117

Human   114 LPTQPLNSEEWDKLKEDLKENTGKT-SFESWIISQMAGCHSSIDVAKSLLAWVAAKNNGIVSYDL 177
            :|..||:::||.||||:    :|:. .||.::::||...:|:|:||||||.:.|.:.:|| ||.|
 Frog   118 IPLGPLHAKEWSKLKEE----SGRIHGFEDYMMAQMISTNSNINVAKSLLVFAAKEQSGI-SYKL 177

Human   178 LVKYLYLCVFHMQTSEVIDVFEIMKARYKTLEPRGYSLLIRGLIHSDRWREALLLLEDIKKVITP 242
            |:|||.|||...|.:||.||:.|||.::|..:...|||.|:|...:||||:::.:||.:||.|||
 Frog   178 LLKYLALCVRQNQAAEVCDVYNIMKNKFKAFDTGAYSLFIKGFSLTDRWRDSISMLETLKKTITP 242

Human   243 SKKNYNDCIQGALLHQDVNTAWNLYQELLGHDIVPMLETLKAFFDFGKDIKDDNYSNKLLDILSY 307
            |.|||..|||||:.|:|...||.||.|:|..|:.|..:.:::.|:....::|:.:.|||..:..|
 Frog   243 SPKNYGYCIQGAIYHKDDKLAWALYNEMLEADLTPCEDAIQSLFNADPALQDETFRNKLFGVFDY 307

Human   308 LRNNQLYPGESFAHSIKTWFESVPGKQWKGQFTTVRKSGQCSGCGKTIESIQLSPEEYECLKGKI 372
            .|::|:||||....|||:||||:|.:.|:|..:||.::|.|..|.:.:|||.|.||||..||...
 Frog   308 FRDHQIYPGEPLMQSIKSWFESIPNESWRGHLSTVSENGHCQVCKQQLESIHLMPEEYRTLKDVF 372

Human   373 MRDVIDGGDQYRKTTPQELKRFENFIKSRPPFDVVIDGLNVAKMFPKVRESQLLLNVVSQLAKRN 437
            ::.||:|.|.:||||||||:.|..|::|.||:|:|:||||||.:..|.|.||.||::||.|....
 Frog   373 LQSVIEGHDTFRKTTPQELQEFRQFVRSHPPYDIVVDGLNVAYITTKGRGSQTLLDIVSGLCSGG 437

Human   438 LRLLVLGRKHMLRRSSQWSRDEMEEVQKQASCFFADDISEDDPFLLYATLHSGNHCRFITRDLMR 502
            .|:|||||||||:.|..|.|..|:.:|::|.|||.|:|||||||||||:|:||:||.|:||||||
 Frog   438 KRVLVLGRKHMLQESRTWQRRHMQLLQQRADCFFIDNISEDDPFLLYASLNSGSHCCFLTRDLMR 502

Human   503 DHKACLPDAKTQRLFFKWQQGHQLAIVNRFPGSKLTFQRILSYDTVVQTTGDSWHIPYDEDLVER 567
            |||:|||||:|:|||||||:||||.:....||.|:..|.|:.|||:||.|..|||||||:..|:|
 Frog   503 DHKSCLPDAQTKRLFFKWQRGHQLVLPFYTPGRKVLLQPIMCYDTIVQRTDFSWHIPYDKMGVDR 567

Human   568 CSCEVPTKWLCLHQK 582
            .|.|||..||||.:|
 Frog   568 ASFEVPKTWLCLQKK 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRORP	NP_055487.2	PPR repeat	174..204	CDD:276811	18/29 (62%)
		PPR repeat	210..239	CDD:276811	12/28 (43%)
		PPR repeat	244..271	CDD:276811	15/26 (58%)
		PRORP	342..578	CDD:465320	136/235 (58%)
prorp	XP_002935379.1	PPR repeat	210..238	CDD:276811	11/27 (41%)
		PPR repeat	244..272	CDD:276811	15/27 (56%)
		PRORP	342..578	CDD:465320	136/235 (58%)