Protein Alignment CLINT1 and lqf

DIOPT Version :10

• Sequence 1: NP_001182484.1
• Gene: CLINT1 / 9685
• HGNCID: 23186
• Length: 643
• Species: Homo sapiens
• Sequence 2: NP_729266.2
• Gene: lqf / 38846
• FlyBaseID: FBgn0028582
• Length: 831
• Species: Drosophila melanogaster
• Alignment Length: 736
• Identity: 190/736 - (25%)
• Similarity: 302/736 - (41%)
• Gaps: 200/736 - (27%)

Human    16 NVVMNYSEIESKVREATNDDPWGPSGQLMGEIAKATFMYEQFPELMNMLWSRMLKDNKKNWRRVY 80
            |:..|||:.:.||||||::||||||..:|.|||:.|:....|.|:|.|:|.| |.|:.||||.||
  Fly    21 NLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKR-LNDHGKNWRHVY 84

Human    81 KSLLLLAYLIRNGSERVVTSAREHIYDLRSLENYHFVDEHGKDQGINIRQKVKELVEFAQDDDRL 145
            |:|:||.|||:.|||:|....:|:|:.:::|..:.:.:| |||||.::|:|.|:||...:||:||
  Fly    85 KALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFEE-GKDQGTHVREKAKQLVTLLKDDERL 148

Human   146 REERKKAKKNKDKYVGVSSDSVGGFRYSERYDPEPKSK-----WDEEWDKNKSAF----PFSDKL 201
            :.||.||:|.|:::    :.:..||. |:.|...|..:     |.||..|:.|..    |.:...
  Fly   149 KNERVKAQKAKERF----AQNPSGFG-SDGYIDGPSQRDLPPGWQEEPPKSVSELEMVRPQTAGE 208

Human   202 GELSDKIGSTIDDTISKFRRKDREDSPERCSD----------SDEEKKARRGRSPKGEFKDEEET 256
            .||..::...:.      |.:..::..:|.||          |:::.|...||......|:|:::
  Fly   209 EELQLQLAMAMS------REEAEQEEAKRRSDDVRLQLALSQSEQDFKDPNGRPIPAPKKEEQQS 267

Human   257 VTTKHIHITQATETTTTRHKRTANPSKTIDLGAAAHYTGDKASPDQNASTHTPQSSVKT-SVPSS 320
                  |:....:               |.|||.:     .:||...|:...|.:.|.. ::|..
  Fly   268 ------HLLDLLD---------------ISLGATS-----ISSPPLGAAGGAPTAVVDPWAMPGP 306

Human   321 KSSGDLVDLFDGTSQSTGGSADLFGGFADFGSAAASGSFPSQVTATSGNGDFGD--WSAFNQAPS 383
            ::...|.|.:.|||..   ..|.:.     .|||......:.|..||.....|:  |.|..|:||
  Fly   307 RAPSQLSDPWSGTSSP---QVDPWN-----PSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPS 363

Human   384 GPVASSGEFF----GSASQ---------PAVE---LVSGSQSALGPPP---AASNSS-------- 421
            ....||.|.:    |:|:|         |..|   :.|.:..|||..|   ||:|.|
  Fly   364 VASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLA 428

Human   422 ---------------------------------------------------DLFDLM----GSSQ 431
                                                               |.|||:    .|..
  Fly   429 EPAASAAGGAAAVGLADPWAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITNRNKSEH 493

Human   432 ATMTSSQSMNFSM------MSTNTVGLGLPMS--------RSQPLQNVSTVLQKPNPLYNQNTDM 482
            :...:|.:.|.|:      :|.|....|:..|        ..:.:::..:.|.:.:.|.|.: ::
  Fly   494 SNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLGENSALVNLD-NL 557

Human   483 VQKSVSKTLPSTWSDPSVNISLDNLLPG----MQPSKPQQPSLNTMIQQQNMQQPMN------VM 537
            ::....:|  .|.:.|:.|...||::|.    .|..:|..||:|.:.||......||      ||
  Fly   558 IKPIAPQT--QTGNQPAYNPFSDNVVPPKTNLFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVM 620

Human   538 TQSFGAVNLSSPSNMLPVRP-------------QTNALIGGP------MPMSMPNVMTGTMGMAP 583
            .   |....|.|....||||             |..:.:..|      :|...||:.........
  Fly   621 G---GVSTTSQPKLPPPVRPTSLNLGPSSVGEFQLLSALSNPIIPIAHIPQPQPNLQVYNNAYQS 682

Human   584 LGNTPMMNQSMMGMNMNIGMS 604
            ..:|.::.:|.:..|||...|
  Fly   683 SSSTNILGKSNIPTNMNSSTS 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CLINT1	NP_001182484.1	ENTH_EpsinR	24..149	CDD:340786	60/124 (48%)
		Nucleoporin_FG2	<304..416	CDD:435043	35/133 (26%)
lqf	NP_729266.2	ENTH_Epsin	28..150	CDD:340787	60/123 (49%)
		UIM	208..227	CDD:197845	3/24 (13%)
		PHA03247	<278..394	CDD:223021	33/128 (26%)