Protein Alignment SOCS5 and Socs5

DIOPT Version :10

• Sequence 1: NP_054730.1
• Gene: SOCS5 / 9655
• HGNCID: 16852
• Length: 536
• Species: Homo sapiens
• Sequence 2: NP_001102744.1
• Gene: Socs5 / 500616
• RGDID: 1564914
• Length: 536
• Species: Rattus norvegicus
• Alignment Length: 536
• Identity: 510/536 - (95%)
• Similarity: 525/536 - (97%)
• Gaps: 0/536 - (0%)

Human     1 MDKVGKMWNNFKYRCQNLFGHEGGSRSENVDMNSNRCLSVKEKNISIGDSTPQQQSSPLRENIAL 65
            |||||||||||||||||||.|||||||||||||:|||||||||::|:|::.|:||||||||||||
  Rat     1 MDKVGKMWNNFKYRCQNLFSHEGGSRSENVDMNANRCLSVKEKSVSLGEAAPRQQSSPLRENIAL 65

Human    66 QLGLSPSKNSSRRNQNCATEIPQIVEISIEKDNDSCVTPGTRLARRDSYSRHAPWGGKKKHSCST 130
            ||||||||..||||||||.||||:||||||||:||..||||||||||||||||||||||||||||
  Rat    66 QLGLSPSKTFSRRNQNCAAEIPQVVEISIEKDSDSSATPGTRLARRDSYSRHAPWGGKKKHSCST 130

Human   131 KTQSSLDADKKFGRTRSGLQRRERRYGVSSVHDMDSVSSRTVGSRSLRQRLQDTVGLCFPMRTYS 195
            |||||||.:|||||||||||||||||||||:|||||||||.||||||||||||||||||||||||
  Rat   131 KTQSSLDTEKKFGRTRSGLQRRERRYGVSSMHDMDSVSSRAVGSRSLRQRLQDTVGLCFPMRTYS 195

Human   196 KQSKPLFSNKRKIHLSELMLEKCPFPAGSDLAQKWHLIKQHTAPVSPHSTFFDTFDPSLVSTEDE 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 KQSKPLFSNKRKIHLSELMLEKCPFPAGSDLAQKWHLIKQHTAPVSPHSTFFDTFDPSLVSTEDE 260

Human   261 EDRLRERRRLSIEEGVDPPPNAQIHTFEATAQVNPLYKLGPKLAPGMTEISGDSSAIPQANCDSE 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||.|||||.|||||
  Rat   261 EDRLRERRRLSIEEGVDPPPNAQIHTFEATAQVNPLYKLGPKLAPGMTEISGDGSAIPQTNCDSE 325

Human   326 EDTTTLCLQSRRQKQRQISGDSHTHVSRQGAWKVHTQIDYIHCLVPDLLQITGNPCYWGVMDRYE 390
            ||:||||||||||||||:|||||:|:|||||||||||||||||||||||||||||||||||||||
  Rat   326 EDSTTLCLQSRRQKQRQVSGDSHSHISRQGAWKVHTQIDYIHCLVPDLLQITGNPCYWGVMDRYE 390

Human   391 AEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYNRSLHARIEQWNHNFSFDAHDPCVFHSSTVTGL 455
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   391 AEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYNRSLHARIEQWNHNFSFDAHDPCVFHSSTVTGL 455

Human   456 LEHYKDPSSCMFFEPLLTISLNRTFPFSLQYICRAVICRCTTYDGIDGLPLPSMLQDFLKEYHYK 520
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   456 LEHYKDPSSCMFFEPLLTISLNRTFPFSLQYICRAVICRCTTYDGIDGLPLPSMLQDFLKEYHYK 520

Human   521 QKVRVRWLEREPVKAK 536
            ||||||||||||||||
  Rat   521 QKVRVRWLEREPVKAK 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SOCS5	NP_054730.1	Required for interaction with IL4R. /evidence=ECO:0000250	1..50		43/48 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	115..175		55/59 (93%)
		SOCS	145..195	CDD:432667	47/49 (96%)
		SH2	370..470	CDD:472789	99/99 (100%)
		SOCS_SOCS5	479..534	CDD:239708	54/54 (100%)
Socs5	NP_001102744.1	SOCS	145..195	CDD:432667	47/49 (96%)
		SH2	370..470	CDD:472789	99/99 (100%)
		SOCS_SOCS5	479..534	CDD:239708	54/54 (100%)