DRSC/TRiP Functional Genomics Resources

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Protein Alignment SOCS5 and F39B2.5

DIOPT Version :10

Sequence 1:NP_054730.1 Gene:SOCS5 / 9655 HGNCID:16852 Length:536 Species:Homo sapiens
Sequence 2:NP_493574.2 Gene:F39B2.5 / 185487 WormBaseID:WBGene00009556 Length:192 Species:Caenorhabditis elegans


Alignment Length:125 Identity:40/125 - (32%)
Similarity:56/125 - (44%) Gaps:18/125 - (14%)


- Green bases have known domain annotations that are detailed below.


Human   382 YWGVMDRYEAEALLEGKPEGTFLLRDSAQEDYLFSVSFRRYNRSLHARIEQWNHNFSFDAHDPCV 446
            |||.:|...||.||...|.|.||:|||..|.:||:||:...:|..|:|:...:...:..:..|.|
 Worm    17 YWGDLDWKWAERLLLLCPIGYFLIRDSRSETHLFTVSYHFQDRVYHSRLSLEDSRRNLGSRQPYV 81

Human   447 FH-------------SSTVTGLLE--HYKDPSSCMFFEPLLTISLNR--TFPFSLQYICR 489
            ..             ..::||..|  ||:...........||..|.:  ..| ||||:||
 Worm    82 SRDYWNLVEIIERSLEQSLTGQQEMLHYRRGHEAEAARVNLTRPLTKRELLP-SLQYLCR 140

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SOCS5NP_054730.1 Required for interaction with IL4R. /evidence=ECO:0000250 1..50
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 115..175
SOCS 145..195 CDD:432667
SH2 370..470 CDD:472789 30/102 (29%)
SOCS_SOCS5 479..534 CDD:239708 7/11 (64%)
F39B2.5NP_493574.2 SH2_SOCS7 5..106 CDD:198251 27/88 (31%)
SOCS 126..169 CDD:128549 8/16 (50%)
Blue background indicates that the domain is not in the aligned region.

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