|
Human 433 PPLELLAERESLY-RLLPQTTPENINKNFEQYTLDPGTRYPNLNSHCVRPHQVKHLYITKELEHY 496
||.:::...|..| |.|| |.:.|...:..::..:.:.||
Fly 181 PPAKMIRSSELEYRRALP----------------------PAIESSSTQRREISDIVVGKE---- 219
Human 497 PLERLGSVRRSVNLSRKESDIRPSKLLTWCQQQTEGYQHVNVTDLTTSWRSGLALCAIIHRFRPE 561
.|:|.:|: ||.|.::.|..|..|.|.|.|:|||.|||..|::||.||:
Fly 220 -----------DNVSAREA------LLRWARRSTARYPGVRVNDFTSSWRDGLAFSALVHRNRPD 267
Human 562 LINFDSLNEDDAVENNQLAFDVAEREFGIPPVTTGKEMASAQEPDKLSMVMYLSKFYELFRGT-- 624
|:::.....|...|..:.||.:.|:|:|:..:...::: ...|||:.|::.|:|..|::|...
Fly 268 LLDWRKARNDRPRERLETAFHIVEKEYGVTRLLDPEDV-DTNEPDEKSLITYISSLYDVFPEPPS 331
Human 625 --PLRPVDSWRKNYGENADL------------------SLAKSSISNNYLNLTFPRKRTPRVDGQ 669
||..::|.|:.: |..|| |...:.|....|.....|.|:..|..:
Fly 332 IHPLFDMESQRRVH-EYRDLAQQFIYWCREKTAYLQERSFPPTLIEMKRLLSDLQRFRSDEVSAR 395
Human 670 --------------------TGENDMNKRRRKGFTNLDEPSNFSSRSLGSNQECGSSKEGGNQNK 714
.||.|:....| .:..|.:.:...:...::|....:|.....:
Fly 396 KREKSKLIQIYKELERYFETVGEVDVEAELR---PDAIEKAWYRMNTALQDREVILQQEIERLER 457
Human 715 VKSMANQLLAKFEESTRNPSLMKQERRVSGIGKPVLCSSSGPPVHSCCPKP-EEATPSPSPPLKR 778
::.:|:::..:.:.. :..|...|.|:...|:.: ..:|....|. .||..:....|:.
Fly 458 LQRLADKVQREIKHV--DQKLTDLEGRIGEEGRRI------ERLHPVDAKSIVEALETEIRHLEE 514
Human 779 QFPSVVVTGHVLRE-----LKQVSAGSECLSRPWRARAKSDLQLGGTENFATLPSTRPRAQALSG 838
....:....|||.| :.::......|.:.| |:.:: ||.| ...|.|||
Fly 515 PIQDMNQDCHVLNEGRYPHVSELHKKVNKLHQRW-AQLRT--------NFHT-----NLVQKLSG 565
Human 839 VLWRLQQVEEKILQKRAQNLANREFHTKNIKEKAAHLASMFGHGDFPQNKLLSKGLSHTHPPSPP 903
:.:.:. |..:.::....:.:|:..|. .|...:..|.::.||||
Fly 566 LKYPVH--ETTVTRQTRMVVESRQIDTN------PHFRDLQEHIEWCQNKL-------------- 608
Human 904 SRLPSPDPAASSSPSTVDSASPARKEKKSPSGFHFHPSHLRTVHPQLTVGKVSSGIGAAAEVLVN 968
.:|.:.| ..|..||..:.....:.|.|....|| .
Fly 609 KQLLAAD-YGSDLPSVKEELDRQQHEHKIIDQFH------------------------------T 642
Human 969 LYMNDHRPKAQATSPDLESMRKSFPLNLGGSDTCYFCKKRVYVMERLSAEGHFFHRECFRCSICA 1033
..:||.|.:.:.:..:|. ..::|:..::::.|| .:..
Fly 643 KILNDERQQTKFSGDELA-----------------LYQQRLNQLQKVYAE-----------LLST 679
Human 1034 TTLRLAAYTFDCDEGKFYCKPHFIHCKTNSKQRKRRAEL-----KQQREEEATWQEQEAPRRDTP 1093
:|.||: |.|. ..||: .:..||| |:|.|....|.:::. |.|
Fly 680 STKRLS----DLDS-----LQHFL--------GQASAELQWLNEKEQVEITRDWADKQL---DLP 724
Human 1094 TESSCAVAAIGTLEGSPPDEPTSPKRPKSISEPQHSDAEGDAA--SPLPSEW------------- 1143
:........:..||.......|...|.:::...||..::...| :.|..:|
Fly 725 SVHRYYENLMSELEKREMHFATILDRGEALLNQQHPASKCIEAHLTALQQQWAWLLQLTLCLEVH 789
Human 1144 ----TSVRISPGEEAAGQDVLAVRVLVTSEDSSSDTESDYGGSEGSHTEPCEEKPWRPGSPHLPH 1204
|......||....:..||.|..:. :|..::||:|..:
Fly 790 LKHATEYHQFFGEIKDAEQWLAKRDEIL---NSKFSQSDFGLDQ--------------------- 830
Human 1205 TSLGEALSRAVSPQCPEEPRA---VHAALQRANSFQSPTPSKYQNWRREFWWSLTPVNK------ 1260
||.|.|.:. ...||..| ..|.|||......|. |.||: |||:
Fly 831 ---GETLLRGMQ-DLREELNAFGETVATLQRRAQTVVPL-----NKRRQ------PVNRQGPVQA 880
Human 1261 -------------------------------RTMSPPKDPSPS--LPLPSSSSHSSSPPSSSSTS 1292
||....:.|.|. |.|| ||...:..
Fly 881 ICAYKQQGQLQIEKGETVTLLDNSGRVKWRVRTAKGQEGPIPGACLLLP--------PPDQEAID 937
Human 1293 ----------------------------------VSGNAPD---GSSPPQMTA------SEPLSQ 1314
|.|...| ...|.|.|| .:....
Fly 938 AAERLKRLFDRSVALWQKKHLRLRQNMIFATIRVVKGWDFDQFLAMGPEQRTAIRRALNDDADKL 1002
Human 1315 VSRGHPSPPT---------------PNFRRRAVAQGAPREIPLYLPHHPKPEWAEYCLVSPGEDG 1364
:|.|.|:.|. ..|.:||.|:...::.... :.|.||....:
Fly 1003 LSEGDPNDPQLRRLRREMDEVNRLFDEFEKRARAEEESKQASRI--------FTEECLAIKSK-- 1057
Human 1365 LSDPAEMTSDECQPAEAPL-GDIGSNHR--DPHPIWGKDRSWTGQELSPLAGEDREKGSTGARKE 1426
|.| |..:..|...||| .|:.|... :.|..:.:.......||..| :|...|.|.|.
Fly 1058 LED---MARELDQIILAPLPRDLDSLEHVLEIHSDYERRLHLLEPELKHL----QETFRTIALKT 1115
Human 1427 EEGGPVLVKE-------------KLGLKK--LVLTQEQKTMLLDWNDSIPESVHLKAGERISQKS 1476
|||.|. :.||.| |.|.:.....|.|....|.|..:..|..:....:
Fly 1116 ----PVLKKSLDNLMELWKELNTQSGLHKDRLKLLEASLAGLEDNEHVISELENELARHQDLPST 1176
Human 1477 AENGRGGRVLKPVRPLLLPRAAGEPLPTQRGAQ-EKMGTPAEQAQGERNVPPPKSPLRLIANAIR 1540
||..: :|.|.:..: :.:.||:..| :||...|:|. |...|| ..:.
Fly 1177 AEGLQ--QVFKQLNHM-------QDIITQQQPQMDKMNDAADQL-GRMGVP----------TKVL 1221
Human 1541 RSLEPLLSNSEGGKKAWA---KQESKTLPAQACTRSFSLRKTNSNKDGDQHSPGRNQSSAFSPPD 1602
..|:.|.||.|.....|: .|..:.: ::|..:..|.|...:....:.|.....:...|...
Fly 1222 GDLKRLHSNVERLNTRWSAVCNQLGERM--RSCETAIGLMKNLQSSVQVEESWVDGTTERLSAMP 1284
Human 1603 PALRTHSLPNRPSKVFPAL--RSPPCSKIEDVPT----LLEKVSLQEN----FPD-------ASK 1650
.|...:.| .|:..|. |.| |||:|.. |:.:..:.:: |.| :..
Fly 1285 TATSAYEL----DKLLGAAIERKP---KIENVNVAGGRLIREAKIYDSKCLRFVDWLVEARPSFS 1342
Human 1651 PPKKRI---------SLFSSLRL------KDKSFESFLQESRQRKDIRDLFGSPKRKVLPEDSAQ 1700
||::.: :.:.|.|| .|:..| |.|::.|...::.|| |..|
Fly 1343 PPRRDLRPADSDPGATQYYSQRLDNLNTKNDRLLE---QLSQRLKTAIEVNGS--------DGLQ 1396
Human 1701 ALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPPTAGGADSKNFPL------RAQVTEASSSASSTS 1759
..|.|.:|.|:..:..:| ...||..|..::...| ..|::...::.|||.
Fly 1397 YAESLQKPLKTFRVDFSA----------GSVPTGDGYAARQEDLYTTTYSTTQISSTKTTKSSTK 1451
Human 1760 SSSADEEFD-----------PQLSLQLKEKKTLRRRKKL-EKAMKQL--VKQEELKR-LYKAQAI 1809
|..:.:..| ||..:|..|.:||:|.::| ..::..: ::.....| |...:||
Fly 1452 SVYSSDGLDAASQEVSTAGLPQSQIQFNEIRTLKRSQQLGGHSVLDIAGIRDPRTGRVLTIGEAI 1516
Human 1810 QRQLEEVEERQRASEIQGVRLEKALRGEADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQ 1874
|.::.:|...:.....:.:.||:| ||.|..| .||.::..:....::...|..|.|.::.:
Fly 1517 QLRILDVRTGEMLVGDRRITLEQA----ADQGLID-LQLAKQLLEPGAGRDASGRELSLLEVIQR 1576
Human 1875 EL-ELEDHQSRLEQKLR 1890
|: |.|......|::::
Fly 1577 EISEAESGYETAEKRIK 1593
| 
