DRSC/TRiP Functional Genomics Resources

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Protein Alignment RGS6 and Axn

DIOPT Version :9

Sequence 1:XP_024305527.1 Gene:RGS6 / 9628 HGNCID:10002 Length:684 Species:Homo sapiens
Sequence 2:NP_733336.1 Gene:Axn / 43565 FlyBaseID:FBgn0026597 Length:745 Species:Drosophila melanogaster


Alignment Length:294 Identity:69/294 - (23%)
Similarity:112/294 - (38%) Gaps:45/294 - (15%)


- Green bases have known domain annotations that are detailed below.


Human   302 PAEPSN-PWISDDVALWDIEMSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSEN--L 363
            |.|.|. ..:::.||  |...:..||   ...|..:.:.:|:|:.|.:.|.:::|.|..:.|  |
  Fly    24 PGEESRVKKMTEGVA--DTSKNSSPS---YLNWARTLNHLLEDRDGVELFKKYVEEEAPAYNDHL 83

Human   364 RFWLAVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDG-----GRYTFE 423
            .|:.|.:.||:|...:..|::......||.....|.    |.......:.:|..     ..:.|:
  Fly    84 NFYFACEGLKQQTDPEKIKQIIGAIYRFLRKSQLSI----SDDLRAQIKAIKTNPEIPLSPHIFD 144

Human   424 DAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKPESEQGRRTSLEKFTRSVNVQNTRPAGAWSIF 488
            ..|.|:...::.:.|..||.|..|   :|..::..::|.|.|| ...|.|.:..::...|:....
  Fly   145 PMQRHVEVTIRDNIYPTFLCSEMY---ILYIQQMSAQQERCTS-SGATGSGSAGSSGSGGSSLAG 205

Human   489 MAALPMAVWLRTPRSCHGLSESRLLGLPSLHDGLREGKVAGGQAPHGPDAVLLTVPTAGPGPGPA 553
            ..|||       |.:..|..:...|..|.....|....|:|  .|.|      |...:|...|| 
  Fly   206 ACALP-------PTTASGKQQLPQLVPPGAFINLPVSSVSG--PPAG------TCSASGSVYGP- 254

Human   554 DPTGRRRRSTSADRVSLRGDLVTVKEKDCIPTLH 587
                    ||||..........|:.....:||||
  Fly   255 --------STSASSSGSISATDTLPRSSTLPTLH 280

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RGS6XP_024305527.1 DEP_RGS7-like 31..119 CDD:239897
GGL 258..319 CDD:128520 5/17 (29%)
RGS_RGS6 328..452 CDD:188691 28/130 (22%)
AxnNP_733336.1 RGS 55..170 CDD:295367 27/121 (22%)
Axin_b-cat_bind 494..543 CDD:285982
DIX 665..739 CDD:279160
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3589
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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